NURS 5359 Exam 1 Study Guide 2026 | Complete Review |
Graded A+
1. What are two common side effects of alpha 1 adrenergic receptor blockade?
Increased heart rate and insomnia
Nausea and vomiting
Weight gain and sedation
Dizziness and orthostatic hypotension
2. Describe the relationship between dopamine and prolactin secretion in the
context of antipsychotic medication use.
Antipsychotics have no effect on prolactin levels.
Dopamine stimulates prolactin secretion, and antipsychotics enhance
this effect by blocking D2 receptors.
Prolactin secretion is independent of dopamine action.
Dopamine normally suppresses prolactin secretion, and
antipsychotics block D2 receptors, leading to increased prolactin
levels.
3. What cardiovascular risk is associated with Paliperidone that necessitates
monitoring?
Tachycardia
Hypertension
Bradycardia
QT prolongation
,4. Describe how the blockade of alpha 1 adrenergic receptors can lead to
dizziness.
Dizziness occurs because alpha 1 blockade enhances
neurotransmitter release.
Dizziness is unrelated to alpha 1 adrenergic receptor activity.
Blockade of alpha 1 adrenergic receptors can lead to dizziness due
to impaired vasoconstriction and subsequent drops in blood
pressure upon standing.
Blockade of alpha 1 adrenergic receptors increases heart rate, causing
dizziness.
5. Patients on antipsychotics may experience these consequences:
extrapyramidal side affects, hepatotoxicity, hyperglycemia, and
cataracts.
hypertension, orthostatic hypotension, seizures
extra pyramidal side affects, seizures, death
6. If a patient on a first-generation antipsychotic develops tremors and rigidity,
what condition might they be experiencing?
Extrapyramidal symptoms
Acute Psychosis
Serotonin Syndrome
Neuroleptic Malignant Syndrome
7. If a patient on Clozapine presents with symptoms of fever and sore throat,
what should be the immediate clinical action?
Obtain a complete blood count to check for agranulocytosis.
, Increase the Clozapine dosage.
Discontinue Clozapine immediately without further assessment.
Refer the patient to a psychiatrist for evaluation.
8. If a new antipsychotic medication is approved with an FDA indication for
schizophrenia, how should this influence a clinician's treatment plan?
The clinician should avoid using the medication due to potential side
effects.
The clinician should consider prescribing the new medication for
patients diagnosed with schizophrenia, following the FDA
guidelines.
The clinician should prescribe the medication for any mental health
condition.
The clinician should only use the medication in combination with other
treatments regardless of the indication.
9. Describe the importance of regular monitoring in the management of side
effects from antipsychotic medications.
Regular monitoring only applies to first-generation antipsychotics.
Regular monitoring is only needed for patients with a history of
substance abuse.
Regular monitoring is crucial to identify side effects early and adjust
treatment accordingly.
Regular monitoring is unnecessary as side effects are predictable.
10. This is a life threatening idiosyncratic reaction to an antipsychotic drug
characterized by fever, altered mental status, muscle rigidity, and autonomic
dysfunction.
, Neuroleptic malignant syndrome
Extrapyramidal symptom
Status epilepticus
11. Describe the common side effects associated with Brexpiprazole and their
potential impact on patients.
Common side effects include insomnia and anxiety, which may lead to
discontinuation of the medication.
Common side effects include weight gain, sedation, and
gastrointestinal disturbances, which can affect a patient's quality of
life and adherence to treatment.
Common side effects include dry mouth and blurred vision, which are
generally mild and easily managed.
Common side effects include increased energy and improved mood,
which enhance treatment adherence.
12. Drug manufacturers must provide the FDA with evidence supporting the use
of their drug for a certain indication. In this context, what is an indication?
A medical condition which can be healed by the drug in one day
A situation in which use of the drug should be avoided
A diagnostic technique that will help indicate where the pathology is
in the body
A condition that the drug has a therapeutic effect on
The proper dosage for the drug
13. A patient on an antipsychotic medication presents with dizziness upon
standing. Which receptor blockade might be responsible for this side effect?
Graded A+
1. What are two common side effects of alpha 1 adrenergic receptor blockade?
Increased heart rate and insomnia
Nausea and vomiting
Weight gain and sedation
Dizziness and orthostatic hypotension
2. Describe the relationship between dopamine and prolactin secretion in the
context of antipsychotic medication use.
Antipsychotics have no effect on prolactin levels.
Dopamine stimulates prolactin secretion, and antipsychotics enhance
this effect by blocking D2 receptors.
Prolactin secretion is independent of dopamine action.
Dopamine normally suppresses prolactin secretion, and
antipsychotics block D2 receptors, leading to increased prolactin
levels.
3. What cardiovascular risk is associated with Paliperidone that necessitates
monitoring?
Tachycardia
Hypertension
Bradycardia
QT prolongation
,4. Describe how the blockade of alpha 1 adrenergic receptors can lead to
dizziness.
Dizziness occurs because alpha 1 blockade enhances
neurotransmitter release.
Dizziness is unrelated to alpha 1 adrenergic receptor activity.
Blockade of alpha 1 adrenergic receptors can lead to dizziness due
to impaired vasoconstriction and subsequent drops in blood
pressure upon standing.
Blockade of alpha 1 adrenergic receptors increases heart rate, causing
dizziness.
5. Patients on antipsychotics may experience these consequences:
extrapyramidal side affects, hepatotoxicity, hyperglycemia, and
cataracts.
hypertension, orthostatic hypotension, seizures
extra pyramidal side affects, seizures, death
6. If a patient on a first-generation antipsychotic develops tremors and rigidity,
what condition might they be experiencing?
Extrapyramidal symptoms
Acute Psychosis
Serotonin Syndrome
Neuroleptic Malignant Syndrome
7. If a patient on Clozapine presents with symptoms of fever and sore throat,
what should be the immediate clinical action?
Obtain a complete blood count to check for agranulocytosis.
, Increase the Clozapine dosage.
Discontinue Clozapine immediately without further assessment.
Refer the patient to a psychiatrist for evaluation.
8. If a new antipsychotic medication is approved with an FDA indication for
schizophrenia, how should this influence a clinician's treatment plan?
The clinician should avoid using the medication due to potential side
effects.
The clinician should consider prescribing the new medication for
patients diagnosed with schizophrenia, following the FDA
guidelines.
The clinician should prescribe the medication for any mental health
condition.
The clinician should only use the medication in combination with other
treatments regardless of the indication.
9. Describe the importance of regular monitoring in the management of side
effects from antipsychotic medications.
Regular monitoring only applies to first-generation antipsychotics.
Regular monitoring is only needed for patients with a history of
substance abuse.
Regular monitoring is crucial to identify side effects early and adjust
treatment accordingly.
Regular monitoring is unnecessary as side effects are predictable.
10. This is a life threatening idiosyncratic reaction to an antipsychotic drug
characterized by fever, altered mental status, muscle rigidity, and autonomic
dysfunction.
, Neuroleptic malignant syndrome
Extrapyramidal symptom
Status epilepticus
11. Describe the common side effects associated with Brexpiprazole and their
potential impact on patients.
Common side effects include insomnia and anxiety, which may lead to
discontinuation of the medication.
Common side effects include weight gain, sedation, and
gastrointestinal disturbances, which can affect a patient's quality of
life and adherence to treatment.
Common side effects include dry mouth and blurred vision, which are
generally mild and easily managed.
Common side effects include increased energy and improved mood,
which enhance treatment adherence.
12. Drug manufacturers must provide the FDA with evidence supporting the use
of their drug for a certain indication. In this context, what is an indication?
A medical condition which can be healed by the drug in one day
A situation in which use of the drug should be avoided
A diagnostic technique that will help indicate where the pathology is
in the body
A condition that the drug has a therapeutic effect on
The proper dosage for the drug
13. A patient on an antipsychotic medication presents with dizziness upon
standing. Which receptor blockade might be responsible for this side effect?
