D027 COMPREHENSIVE EXAM PREP
QUESTIONS AND SOLUTIONS VERIFIED
STUDY RESOURCE
●● What is Klinefelter syndrome?
Answer: An extra X chromosome for males so example XXY causing
female-like qualities
●● What is Turner Syndrome?
Answer: females. missing or deformed x chromosome. right hemisphere
dysfunction, hearing loss, ear infection, language and articulation
disorders, visual spatial and attentional problems
●● What is beta thalassemia?
Answer: a condition in which the synthesis of the beta-globin chains is
decreased or absent. Causes low hemoglobin.
●● Which medication is contraindicated in a patient with Beta
Thalassemia?
Answer: Ferrous Sulfate
●● What drug is used in combination with other agent to treat lymphoid
tissue (leukemia). Directly toxic to lymphoid tissues Selective estrogen
,receptor modulators (SERM) - for hormone receptor positive and
advanced breast cancer. (Tomaxafin - reduces risk and recurrence risk)
Answer: Glucocorticoids
●● What is the normal ejection fraction?
Answer: 55-60%. Less than 50% is BAD
●● Is an ejection fraction of 50% reduced or preserved?
Answer: Preserved
●● What are symptoms of left sided heart failure?
Answer: Think PULMONARY. JVD, FVO, rails, S3 murmurs. Number
one cause of right sided heart failure!
●● What are symptoms of right sided heart failure?
Answer: Think peripheral vascular. Lower extremity edema, abdominal
distension.
●● What is the gold standard lab test for heart failure?
Answer: BNP. Heart failure is a result greater than 100
●● What heart disease is worse with exertion?
, Answer: Ischemic heart disease because the demand requirements are
higher.
●● What should you assess before giving Digoxin?
Answer: Apical pulse
●● How should Warfarin be started?
Answer: Start initial dose at half to monitor the effects
●● What causes the destruction of alveolar walls? Air goes in but can't
get out which leads to hyperinflation
Answer: Emphysema
●● What causes excess mucus production and smooth muscle
hypertrophy?
Answer: Bronchitis
●● What is a chronic inflammatory obstruction of bronchi?
Answer: Asthma, Triggers cause mucus to clog bronchial tubes.
●● What causes an overbite and buffalo hump?
Answer: Endocrine disorder called acromegaly (overproduction of
growth hormone)
QUESTIONS AND SOLUTIONS VERIFIED
STUDY RESOURCE
●● What is Klinefelter syndrome?
Answer: An extra X chromosome for males so example XXY causing
female-like qualities
●● What is Turner Syndrome?
Answer: females. missing or deformed x chromosome. right hemisphere
dysfunction, hearing loss, ear infection, language and articulation
disorders, visual spatial and attentional problems
●● What is beta thalassemia?
Answer: a condition in which the synthesis of the beta-globin chains is
decreased or absent. Causes low hemoglobin.
●● Which medication is contraindicated in a patient with Beta
Thalassemia?
Answer: Ferrous Sulfate
●● What drug is used in combination with other agent to treat lymphoid
tissue (leukemia). Directly toxic to lymphoid tissues Selective estrogen
,receptor modulators (SERM) - for hormone receptor positive and
advanced breast cancer. (Tomaxafin - reduces risk and recurrence risk)
Answer: Glucocorticoids
●● What is the normal ejection fraction?
Answer: 55-60%. Less than 50% is BAD
●● Is an ejection fraction of 50% reduced or preserved?
Answer: Preserved
●● What are symptoms of left sided heart failure?
Answer: Think PULMONARY. JVD, FVO, rails, S3 murmurs. Number
one cause of right sided heart failure!
●● What are symptoms of right sided heart failure?
Answer: Think peripheral vascular. Lower extremity edema, abdominal
distension.
●● What is the gold standard lab test for heart failure?
Answer: BNP. Heart failure is a result greater than 100
●● What heart disease is worse with exertion?
, Answer: Ischemic heart disease because the demand requirements are
higher.
●● What should you assess before giving Digoxin?
Answer: Apical pulse
●● How should Warfarin be started?
Answer: Start initial dose at half to monitor the effects
●● What causes the destruction of alveolar walls? Air goes in but can't
get out which leads to hyperinflation
Answer: Emphysema
●● What causes excess mucus production and smooth muscle
hypertrophy?
Answer: Bronchitis
●● What is a chronic inflammatory obstruction of bronchi?
Answer: Asthma, Triggers cause mucus to clog bronchial tubes.
●● What causes an overbite and buffalo hump?
Answer: Endocrine disorder called acromegaly (overproduction of
growth hormone)
