,• Introduction:
• Most abundant organic molecule of living system
• Occur in every part of cell
• Constitute about 50% of cellular dry weight
• Fundamental basis of structure and function of life
• Protein derived from proteios meaning holding first place
• Berzelius (Swedish chemist) suggested the name proteins to the group of
organic compounds that are utmost important to life.
• Mulder (Dutch chemist) in 1838 used the term proteins for the high
molecular weight nitrogen rich and most abundant substances present in
animals and plants.
• Certain proteins are primarily responsible for structure and strength of body.
These include collagen and elastin found in bone matrix and vascular system
,• Proteins also act as enzymes, hormones, blood clotting factors,
immunoglobulins, membrane receptors, storage proteins, besides their
function in genetic control, muscle contraction, respiration etc.
• Proteins are predominantly constituted by five major elements in the
following proportion.
• Besides the above, proteins may also contain other elements such as P,
Fe, Cu, I, Mg, Mn, Zn etc.
• Nitrogen, an essential component of proteins, on an average is 16%.
, • Proteins as polymers:
• Proteins are the polymers of L-
α-amino acids because on
hydrolysis all proteins yield L-
α-amino acids