HESI RN Exit Exam V6 2026 – Complete
Study Guide with NGN-Style Questions
& Answers | 100% Verified
Instant PDF Download
Instant PDF Download
160 NGN-style exam questions · Detailed rationales · Why wrong answers · 2026 updated
Written by Nursingsolutions, RN, MSN – 9 years Med-Surg Nursing Instructor
HESI RN Exit Exam: 97% | Verified: 2026 Academic Year
Description
This comprehensive HESI RN Exit Exam V6 2026 study guide contains 160 Next Generation NCLEX (NGN) style
practice questions that mirror the actual exam in content, difficulty, and structure. Each question is paired with a
100% verified correct answer, a detailed rationale, and a "Why Wrong" breakdown for every incorrect option.
Updated for the 2026 testing cycle, this guide is designed to help nursing students and RN candidates achieve a high
score and pass the HESI RN Exit Exam with confidence.
Abstract
This document provides a complete review of the HESI RN Exit Exam V6 through 160 NGN-style exam questions
covering all seven core sections: Medical-Surgical Nursing (~30), Pharmacology (~25), Mental Health Nursing (~20),
Maternal-Newborn / OB (~20), Pediatric Nursing (~20), Fundamentals & Leadership (~25), and Community /
Geriatrics (~20). Each question is paired with a 100% verified correct answer, a detailed rationale, and a thorough
"Why Wrong" breakdown. Updated for the 2026 testing cycle, this study guide is designed to help nursing students
and RN candidates achieve a high score and pass the HESI RN Exit Exam with guaranteed accuracy.
Key Features
160 NGN-style exam questions with verified correct answers
Detailed pharmacology and nursing rationales for each question
"Why Wrong" sections for every incorrect option (A, B, C, D)
Covers all HESI RN Exit Exam content areas with accurate weight distribution
Includes medication safety, dosage calculations, adverse effects, and nursing implications
Based on the HESI RN Exit Exam blueprint and NCLEX-RN standards
High-yield content for RNs, nursing students, and healthcare professionals
Instant PDF download – start studying immediately
, Latest Updates
Updated for the 2026 HESI RN Exit Exam testing cycle
Reflects current NGN format and pharmacology guidelines
Includes new questions on high-alert medications, drug interactions, and patient education
Aligns with the latest NCLEX-RN test plan and HESI exam blueprint
Keywords
HESI RN Exit Exam V6, NGN format, complete study guide, HESI exam review, nursing exit exam, RN pharmacology,
medical-surgical nursing, mental health nursing, maternal-newborn nursing, pediatric nursing, fundamentals of
nursing, leadership nursing, community health nursing, geriatrics nursing, NCLEX-RN preparation, nursing school
exam, nursing study guide, 2026 nursing exam, verified answers, graded A+.
Answer Format
Each question includes four answer choices (A, B, C, D)
Correct answer is clearly marked and highlighted
Rationale explains the pharmacology and nursing reasoning behind the correct answer
"Why Wrong" section provides a targeted explanation for each incorrect option
References are included for each question to support evidence-based practice
Compliance Checklist
Aligned with HESI RN Exit Exam blueprint and NCLEX-RN standards
Content reflects current nursing practice and pharmacology guidelines
Questions are written at the appropriate difficulty level for RN candidates
Rationales are evidence-based and cite authoritative sources
Format is designed for effective study and exam preparation
Section Questions Weight
Medical-Surgical Nursing ~30 19%
Pharmacology ~25 16%
Mental Health Nursing ~20 13%
Maternal-Newborn / OB ~20 13%
Pediatric Nursing ~20 13%
Fundamentals & Leadership ~25 16%
Community / Geriatrics ~20 13%
,Medical-Surgical Nursing (30 questions)
Q1. A 72-year-old patient with a history of heart failure (ejection fraction 30%) and
chronic kidney disease stage 3 is admitted with acute decompensated heart failure. The
patient reports worsening dyspnea, orthopnea, and a 3-kg weight gain over 4 days.
Vital signs: BP 158/94, HR 104, RR 28, SpO2 88% on 2L NC. JVP is elevated at 14 cm H2O,
crackles are heard bilaterally to the mid-scapular area, and 2+ pitting edema is noted in
the lower extremities. Current medications include furosemide 40 mg BID, lisinopril 20
mg daily, carvedilol 25 mg BID, and allopurinol 300 mg daily for gout. Which
intervention should the nurse implement first?
A Administer IV furosemide 80 mg bolus and monitor urine output
B Place the patient in high-Fowler position and apply supplemental oxygen at 4 L/min
C Hold carvedilol due to worsening heart failure and bradycardia
D Increase lisinopril to 40 mg daily to reduce afterload
Correct answer: B. Place the patient in high-Fowler position and apply supplemental
oxygen at 4 L/min
Rationale: The priority intervention for acute decompensated heart failure is to improve
oxygenation and reduce preload. High-Fowler position improves lung expansion and
oxygenation, while supplemental oxygen corrects hypoxemia (SpO2 88%). IV diuretics are
important but should be given after positioning and oxygen. Carvedilol should not be held
abruptly in acute decompensation unless the patient is hypotensive or severely
bradycardic. Increasing lisinopril is not the immediate priority and could worsen renal
function in CKD.
Why Wrong:
A: IV diuretics are important but not the first step; airway and breathing are priority.
Oxygen and positioning must be addressed first.
C: Holding carvedilol abruptly can precipitate rebound tachycardia and worsening
heart failure. It should be continued with caution.
D: Increasing lisinopril is not the immediate priority and may worsen renal function in
CKD.
Reference: HESI RN Exit Exam V6 blueprint · NGN NCLEX-RN Test Plan · Saunders Comprehensive
Review.
, Q2. A 55-year-old patient with a history of diabetes type 2, hypertension, and
hyperlipidemia is admitted with acute chest pain. The patient reports substernal chest
pressure radiating to the left arm, accompanied by nausea and diaphoresis. Vital signs:
BP 162/94, HR 98, RR 20, SpO2 95% on room air. An ECG shows ST-segment depression
in leads V1-V4. Troponin I is elevated at 2.5 ng/mL. The patient is started on aspirin,
heparin, and nitroglycerin. Which additional medication should the nurse anticipate
administering?
A Clopidogrel 300 mg loading dose
B Metoprolol 5 mg IV push
C Lisinopril 10 mg PO
D Atorvastatin 80 mg PO
Correct answer: A. Clopidogrel 300 mg loading dose
Rationale: The patient has a non-ST elevation myocardial infarction (NSTEMI) with
elevated troponin. Dual antiplatelet therapy (aspirin + clopidogrel) is indicated for NSTEMI
to prevent further thrombotic events. Metoprolol is indicated but should be given after
stabilization. Lisinopril is indicated but not the priority. Atorvastatin is indicated but
clopidogrel is the priority for acute management.
Why Wrong:
B: Metoprolol is indicated but clopidogrel is the priority for dual antiplatelet therapy.
C: Lisinopril is indicated for secondary prevention but not the immediate priority.
D: Atorvastatin is indicated but clopidogrel is the priority for acute management.
Reference: HESI RN Exit Exam V6 blueprint · NGN NCLEX-RN Test Plan · Saunders Comprehensive
Review.
Study Guide with NGN-Style Questions
& Answers | 100% Verified
Instant PDF Download
Instant PDF Download
160 NGN-style exam questions · Detailed rationales · Why wrong answers · 2026 updated
Written by Nursingsolutions, RN, MSN – 9 years Med-Surg Nursing Instructor
HESI RN Exit Exam: 97% | Verified: 2026 Academic Year
Description
This comprehensive HESI RN Exit Exam V6 2026 study guide contains 160 Next Generation NCLEX (NGN) style
practice questions that mirror the actual exam in content, difficulty, and structure. Each question is paired with a
100% verified correct answer, a detailed rationale, and a "Why Wrong" breakdown for every incorrect option.
Updated for the 2026 testing cycle, this guide is designed to help nursing students and RN candidates achieve a high
score and pass the HESI RN Exit Exam with confidence.
Abstract
This document provides a complete review of the HESI RN Exit Exam V6 through 160 NGN-style exam questions
covering all seven core sections: Medical-Surgical Nursing (~30), Pharmacology (~25), Mental Health Nursing (~20),
Maternal-Newborn / OB (~20), Pediatric Nursing (~20), Fundamentals & Leadership (~25), and Community /
Geriatrics (~20). Each question is paired with a 100% verified correct answer, a detailed rationale, and a thorough
"Why Wrong" breakdown. Updated for the 2026 testing cycle, this study guide is designed to help nursing students
and RN candidates achieve a high score and pass the HESI RN Exit Exam with guaranteed accuracy.
Key Features
160 NGN-style exam questions with verified correct answers
Detailed pharmacology and nursing rationales for each question
"Why Wrong" sections for every incorrect option (A, B, C, D)
Covers all HESI RN Exit Exam content areas with accurate weight distribution
Includes medication safety, dosage calculations, adverse effects, and nursing implications
Based on the HESI RN Exit Exam blueprint and NCLEX-RN standards
High-yield content for RNs, nursing students, and healthcare professionals
Instant PDF download – start studying immediately
, Latest Updates
Updated for the 2026 HESI RN Exit Exam testing cycle
Reflects current NGN format and pharmacology guidelines
Includes new questions on high-alert medications, drug interactions, and patient education
Aligns with the latest NCLEX-RN test plan and HESI exam blueprint
Keywords
HESI RN Exit Exam V6, NGN format, complete study guide, HESI exam review, nursing exit exam, RN pharmacology,
medical-surgical nursing, mental health nursing, maternal-newborn nursing, pediatric nursing, fundamentals of
nursing, leadership nursing, community health nursing, geriatrics nursing, NCLEX-RN preparation, nursing school
exam, nursing study guide, 2026 nursing exam, verified answers, graded A+.
Answer Format
Each question includes four answer choices (A, B, C, D)
Correct answer is clearly marked and highlighted
Rationale explains the pharmacology and nursing reasoning behind the correct answer
"Why Wrong" section provides a targeted explanation for each incorrect option
References are included for each question to support evidence-based practice
Compliance Checklist
Aligned with HESI RN Exit Exam blueprint and NCLEX-RN standards
Content reflects current nursing practice and pharmacology guidelines
Questions are written at the appropriate difficulty level for RN candidates
Rationales are evidence-based and cite authoritative sources
Format is designed for effective study and exam preparation
Section Questions Weight
Medical-Surgical Nursing ~30 19%
Pharmacology ~25 16%
Mental Health Nursing ~20 13%
Maternal-Newborn / OB ~20 13%
Pediatric Nursing ~20 13%
Fundamentals & Leadership ~25 16%
Community / Geriatrics ~20 13%
,Medical-Surgical Nursing (30 questions)
Q1. A 72-year-old patient with a history of heart failure (ejection fraction 30%) and
chronic kidney disease stage 3 is admitted with acute decompensated heart failure. The
patient reports worsening dyspnea, orthopnea, and a 3-kg weight gain over 4 days.
Vital signs: BP 158/94, HR 104, RR 28, SpO2 88% on 2L NC. JVP is elevated at 14 cm H2O,
crackles are heard bilaterally to the mid-scapular area, and 2+ pitting edema is noted in
the lower extremities. Current medications include furosemide 40 mg BID, lisinopril 20
mg daily, carvedilol 25 mg BID, and allopurinol 300 mg daily for gout. Which
intervention should the nurse implement first?
A Administer IV furosemide 80 mg bolus and monitor urine output
B Place the patient in high-Fowler position and apply supplemental oxygen at 4 L/min
C Hold carvedilol due to worsening heart failure and bradycardia
D Increase lisinopril to 40 mg daily to reduce afterload
Correct answer: B. Place the patient in high-Fowler position and apply supplemental
oxygen at 4 L/min
Rationale: The priority intervention for acute decompensated heart failure is to improve
oxygenation and reduce preload. High-Fowler position improves lung expansion and
oxygenation, while supplemental oxygen corrects hypoxemia (SpO2 88%). IV diuretics are
important but should be given after positioning and oxygen. Carvedilol should not be held
abruptly in acute decompensation unless the patient is hypotensive or severely
bradycardic. Increasing lisinopril is not the immediate priority and could worsen renal
function in CKD.
Why Wrong:
A: IV diuretics are important but not the first step; airway and breathing are priority.
Oxygen and positioning must be addressed first.
C: Holding carvedilol abruptly can precipitate rebound tachycardia and worsening
heart failure. It should be continued with caution.
D: Increasing lisinopril is not the immediate priority and may worsen renal function in
CKD.
Reference: HESI RN Exit Exam V6 blueprint · NGN NCLEX-RN Test Plan · Saunders Comprehensive
Review.
, Q2. A 55-year-old patient with a history of diabetes type 2, hypertension, and
hyperlipidemia is admitted with acute chest pain. The patient reports substernal chest
pressure radiating to the left arm, accompanied by nausea and diaphoresis. Vital signs:
BP 162/94, HR 98, RR 20, SpO2 95% on room air. An ECG shows ST-segment depression
in leads V1-V4. Troponin I is elevated at 2.5 ng/mL. The patient is started on aspirin,
heparin, and nitroglycerin. Which additional medication should the nurse anticipate
administering?
A Clopidogrel 300 mg loading dose
B Metoprolol 5 mg IV push
C Lisinopril 10 mg PO
D Atorvastatin 80 mg PO
Correct answer: A. Clopidogrel 300 mg loading dose
Rationale: The patient has a non-ST elevation myocardial infarction (NSTEMI) with
elevated troponin. Dual antiplatelet therapy (aspirin + clopidogrel) is indicated for NSTEMI
to prevent further thrombotic events. Metoprolol is indicated but should be given after
stabilization. Lisinopril is indicated but not the priority. Atorvastatin is indicated but
clopidogrel is the priority for acute management.
Why Wrong:
B: Metoprolol is indicated but clopidogrel is the priority for dual antiplatelet therapy.
C: Lisinopril is indicated for secondary prevention but not the immediate priority.
D: Atorvastatin is indicated but clopidogrel is the priority for acute management.
Reference: HESI RN Exit Exam V6 blueprint · NGN NCLEX-RN Test Plan · Saunders Comprehensive
Review.
