The University of Texas at Arlington NURS 5315
NURS 5315 UTA Exam 2 with question and answer 100% correct
C
Terms in this set (106)
HIV EIA (3rd generation immunoassay) can use urine, saliva, or serum (most accurate), need to wait
until 12 weeks post exposure to see antibodies, >99% accurate
4th generation immunoassay- "gold standard"
measures P24 antigen
can test 10 days post exposure
Mast cell Cellular bags of granules located in loose connective tisssue
close to blood vessels. Activation initiates inflammatory
process.
Histamine Causes vasodilation, increases vascular permeability, increases
blood flow to the site of injury- causes erythema and swelling.
Cytokines Soluble factors that contribute to the regulation of innate or
adaptive resistance by affecting other neighboring cells. Can
be pro-inflammatory or anti-inflammatory. Can react quickly
or be more delayed.
, Leukotrines Released when mast cells degranulate, prolong the
inflammatory process. Cause vasodilation, attract neutrophils,
monocytes, and eosinophils.target of inhibition for singular.
Prostaglandins Released when mast cells degranulate, are produced by the
arachidonic pathway. Cause vasodilation, platelet aggregation
at site of injury, pain, and fever.
Chemotactic factors Biochemical substance that attracts leukocyte to the site of
inflammation
Neutrophils Predominant leukocyte at work during the early stages of
acute inflammation
Monocytes Become macrophages when entering the tissue, responsible
for presenting antigens to the CD4 cell which triggers T-cell
immunity and B-cell immunity.
Releases additional cytokines IL1, IL6, TNF.
Cytokine IL1 function Causes fever, activates phagocytes & lymphocytes and also
increases the release of IL6a
Cytokine IL6 function Stimulates production of acute phase reactants and promotes
growth and stimulation of RBCs
Cytokine TNF function Causes fever, increases synthesis of proinflammatory proteins
by liver, causes muscle wasting, induces thrombosis
Cytokine growth factor function Promotes production and maturation of neutrophils
Complement Functions include bacterial lysis, vasodilation and increased
vascular permeability, triggers mast cell degranulation,
chemotaxis, and opsonization.
Kinin Converted to bradykinin which is responsible for pain and
chemotaxis, and it increases vascular permeability and
vasodilation.
Coagulation cascade Factor XII activates kinin. Function is to form fibrin mesh to
stop bleeding and trap micro organisms.
COX1 Prostaglandin of arachidonic pathway. Provides
gastroprotection, platelet aggregation, fluid/electrolyte
balance
COX2 Prostaglandin of arachidonic pathway. Responsible for pain,
fever, renal protection, tissue repair, reproduction
development.
NURS 5315 UTA Exam 2 with question and answer 100% correct
C
Terms in this set (106)
HIV EIA (3rd generation immunoassay) can use urine, saliva, or serum (most accurate), need to wait
until 12 weeks post exposure to see antibodies, >99% accurate
4th generation immunoassay- "gold standard"
measures P24 antigen
can test 10 days post exposure
Mast cell Cellular bags of granules located in loose connective tisssue
close to blood vessels. Activation initiates inflammatory
process.
Histamine Causes vasodilation, increases vascular permeability, increases
blood flow to the site of injury- causes erythema and swelling.
Cytokines Soluble factors that contribute to the regulation of innate or
adaptive resistance by affecting other neighboring cells. Can
be pro-inflammatory or anti-inflammatory. Can react quickly
or be more delayed.
, Leukotrines Released when mast cells degranulate, prolong the
inflammatory process. Cause vasodilation, attract neutrophils,
monocytes, and eosinophils.target of inhibition for singular.
Prostaglandins Released when mast cells degranulate, are produced by the
arachidonic pathway. Cause vasodilation, platelet aggregation
at site of injury, pain, and fever.
Chemotactic factors Biochemical substance that attracts leukocyte to the site of
inflammation
Neutrophils Predominant leukocyte at work during the early stages of
acute inflammation
Monocytes Become macrophages when entering the tissue, responsible
for presenting antigens to the CD4 cell which triggers T-cell
immunity and B-cell immunity.
Releases additional cytokines IL1, IL6, TNF.
Cytokine IL1 function Causes fever, activates phagocytes & lymphocytes and also
increases the release of IL6a
Cytokine IL6 function Stimulates production of acute phase reactants and promotes
growth and stimulation of RBCs
Cytokine TNF function Causes fever, increases synthesis of proinflammatory proteins
by liver, causes muscle wasting, induces thrombosis
Cytokine growth factor function Promotes production and maturation of neutrophils
Complement Functions include bacterial lysis, vasodilation and increased
vascular permeability, triggers mast cell degranulation,
chemotaxis, and opsonization.
Kinin Converted to bradykinin which is responsible for pain and
chemotaxis, and it increases vascular permeability and
vasodilation.
Coagulation cascade Factor XII activates kinin. Function is to form fibrin mesh to
stop bleeding and trap micro organisms.
COX1 Prostaglandin of arachidonic pathway. Provides
gastroprotection, platelet aggregation, fluid/electrolyte
balance
COX2 Prostaglandin of arachidonic pathway. Responsible for pain,
fever, renal protection, tissue repair, reproduction
development.
