GUARANTEED
PASS.
A N C C B O A R D C E R T I F I C AT I O N · F N P E X A M R E V I E W
LEIK Comprehensive
Practice Question Bank
Family Nurse Practitioner Certification Review
COMPREHENSIVE COVERAGE:
Oral Cancer · Ophthalmology · Immunizations · Anemia · Pharmacology
— Dermatology · Development · Thyroid · Diabetes · GU · Screening
Edition 1 · July 2026
EXAM FOCUSED HIGH-YIELD CONFIDENCE RATIONALES
ANCC FNP Board Content Maximize your exam score Practice smarter Clear explanations
P r e pa r e · P r a c t i c e · Pa s s
Excellence in Advanced Practice Nursing
, ANCC FNP · LEIK COMPREHENSIVE ORAL CANCER & OPHTHALMOLOGY
Oral Cancer, Macular Degeneration & Glaucoma
How to Use This Guide
Each question is formatted in ANCC FNP board-style. The correct answer is clearly marked regardless of letter position. Review
rationales for clinical reasoning.
S EC T ION 1 : ORA L C A NC ER
1 Most cases of oral cancer involve squamous cell carcinoma of which locations?
A Tongue and floor of the mouth
B Hard palate and gingiva
C Buccal mucosa and retromolar trigone
D Pharyngeal tonsils and soft palate
Why A is correct: Most oral squamous cell carcinomas arise on the lateral border of the tongue and the floor of the
mouth. These areas are most exposed to carcinogens (tobacco, alcohol). Presenting symptoms include painless, ulcerating oral
lesions often present for many months before clinical presentation, with adjacent lymphadenopathy (immobile, nontender nodes
>1 cm).
2 Which of the following is the most potent risk factor for squamous cell carcinoma of the oral cavity?
A Longstanding HPV infection (especially HPV-16), tobacco use, and alcohol misuse
B Poor dental hygiene and periodontal disease
C High intake of spicy foods and hot beverages
D Family history of oral cancer
Why A is correct: The most potent risk factors for oral SCC are longstanding HPV infection (especially HPV-16),
tobacco use, and alcohol misuse. Less potent factors include male gender and advancing age (>55 years at diagnosis). HPV-9
immunization and tobacco avoidance/cessation are key risk reduction strategies.
S EC T ION 2 : OP H T H A L MOLO G Y
PASS.
A N C C B O A R D C E R T I F I C AT I O N · F N P E X A M R E V I E W
LEIK Comprehensive
Practice Question Bank
Family Nurse Practitioner Certification Review
COMPREHENSIVE COVERAGE:
Oral Cancer · Ophthalmology · Immunizations · Anemia · Pharmacology
— Dermatology · Development · Thyroid · Diabetes · GU · Screening
Edition 1 · July 2026
EXAM FOCUSED HIGH-YIELD CONFIDENCE RATIONALES
ANCC FNP Board Content Maximize your exam score Practice smarter Clear explanations
P r e pa r e · P r a c t i c e · Pa s s
Excellence in Advanced Practice Nursing
, ANCC FNP · LEIK COMPREHENSIVE ORAL CANCER & OPHTHALMOLOGY
Oral Cancer, Macular Degeneration & Glaucoma
How to Use This Guide
Each question is formatted in ANCC FNP board-style. The correct answer is clearly marked regardless of letter position. Review
rationales for clinical reasoning.
S EC T ION 1 : ORA L C A NC ER
1 Most cases of oral cancer involve squamous cell carcinoma of which locations?
A Tongue and floor of the mouth
B Hard palate and gingiva
C Buccal mucosa and retromolar trigone
D Pharyngeal tonsils and soft palate
Why A is correct: Most oral squamous cell carcinomas arise on the lateral border of the tongue and the floor of the
mouth. These areas are most exposed to carcinogens (tobacco, alcohol). Presenting symptoms include painless, ulcerating oral
lesions often present for many months before clinical presentation, with adjacent lymphadenopathy (immobile, nontender nodes
>1 cm).
2 Which of the following is the most potent risk factor for squamous cell carcinoma of the oral cavity?
A Longstanding HPV infection (especially HPV-16), tobacco use, and alcohol misuse
B Poor dental hygiene and periodontal disease
C High intake of spicy foods and hot beverages
D Family history of oral cancer
Why A is correct: The most potent risk factors for oral SCC are longstanding HPV infection (especially HPV-16),
tobacco use, and alcohol misuse. Less potent factors include male gender and advancing age (>55 years at diagnosis). HPV-9
immunization and tobacco avoidance/cessation are key risk reduction strategies.
S EC T ION 2 : OP H T H A L MOLO G Y
