NUR 635 ADVANCED PHARMACOLOGY STUDY GUIDE 2026/2027 | PRACTICE QUESTIONS,
VERIFIED ANSWERS & COMPREHENSIVE APRN REVIEW
Pt on heparin in hospital setting. Why start coumadin 2 days before dc? - correct answer
✔✔Because coumadin needs a couple days before it starts working.
Angina: bc pts dev tolerance to long-acting nitroglycerine w/i 1 day. How to prevent? - correct
answer ✔✔Pts must have 8hrs with no nitroglycerine every days. Hint: At night, remove nitro
patch bc no risk of exertional angina
Underlying cause of angina - correct answer ✔✔coronary disease, athlerosclerosis
Why do we give aspirin in pts w/atherosclerosis? - correct answer ✔✔Aspirin is an antiplatelet..
Prevents the existing plaques from getting bigger. Prevents plaque rupture. Cardio protective,
prevents stroke, MI, CVA
What is prescribed for angina pts w/DM? - correct answer ✔✔ACE inhibitors to protect the
kidneys and nerves
SE of high doses of aspirin? - correct answer ✔✔Tinnitus: ringing ears
Pt education regarding Plavix(clopidogrel bisulfate)? - correct answer ✔✔Anti-platelet med. S/sx
bleeding: blood in stool or vomit, excessive bruising, abd pain uterine bld, back pain, petichae.
Interactions with EVERYTHING: OTC, herbals, supplements
Pts on coumadin? What are we watching for? - correct answer ✔✔INR to check therapeutic
levels. Half life is long. Check 12hrs after taking.
What can be caused if pt started on heparin? - correct answer ✔✔day4, ordering blood work to
check platelet count to observe for THROMBOCYTOPENIA
,coumadin and childbearing aged females - correct answer ✔✔Interactions with oral
contraceptives- must have a back up method during time you're taking coumadin
Pregnancy considerations and coumadin - correct answer ✔✔Need to monitor anti-Xa levels
biggest food group interaction with coumadin - correct answer ✔✔Grapefruit, green leafy
veggies. Why? high in vitamin K which counteracts warfarin
Short duration: rapid acting insulin indication, MOA, usage - correct answer ✔✔Given w/meals
Provide bs control between meals at night
Can use in conjunction w/intermediate or long-acting agent
lispro, aspart, gluulocene
Short duration: short acting insulin indication, MOA, usage - correct answer ✔✔Before meals to
control postprandial hyperglycemia
Infused SQ via pump
humulin/regular
intermediate(humalin/novalin) duration insulin indication, MOA, usage - correct answer ✔✔BS
control between meals and during the night
Only one suitable for mixing w/short actings
basal coverage
Long duration: Insulin glargine U100 - correct answer ✔✔up to 24hrs, once daily subq dosing,
basal coverage for DM1 or Dm2
, Neostigmine is a medication uesd to tx what disease/disorder? - correct answer ✔✔Myastenia
Gravis: AI disorder, antibodies destroy communication btw nerves and muscles. S/S weak
skeletal muscles, voluntary muscles, dysphagia, ptosis
Myasthenia gravis is an AI disorder that may cause what s/s? - correct answer ✔✔difficulty
swallowing
Medication must cross _____________ to affect CNS - correct answer ✔✔BBB
Goal in Parkinson's tx is to restore ________________ in brain - correct answer ✔✔dopamine
MCSE of dopaminergics - correct answer ✔✔sleep attacks, hallucinations, confusion
Med appropriate to treat acute psychosis? - correct answer ✔✔Haloperidol
ASE of first-generation antipsychotic(FGA) medications such as haloperidol, chlorpromazine: diff
speaking, chewing - correct answer ✔✔tardive dyskinesia
Med to help manage panic attacks? - correct answer ✔✔SSRI
Cholinesterase inhibitors are used in tx of what conditon? - correct answer ✔✔Alzheimer's
disease. MOA block normal breakdown of acetylocholine which increases their levels and
duration of action in the CNS and PNS (neuromuscular junction). Also used in tx of myasthenia
gravis Ex: neostigmine, donepezil, galantamine, rivastigmine
What are some diseases/disorders/conditions are anticonvulsants used to treat other than
seizure disorders? - correct answer ✔✔migraine HA prevention, bipolar DO, epilepsy Examples:
carbamazepine(Tegretol), gabapentin(Neurontin), phenobarbital, topiramate(Topamax)
VERIFIED ANSWERS & COMPREHENSIVE APRN REVIEW
Pt on heparin in hospital setting. Why start coumadin 2 days before dc? - correct answer
✔✔Because coumadin needs a couple days before it starts working.
Angina: bc pts dev tolerance to long-acting nitroglycerine w/i 1 day. How to prevent? - correct
answer ✔✔Pts must have 8hrs with no nitroglycerine every days. Hint: At night, remove nitro
patch bc no risk of exertional angina
Underlying cause of angina - correct answer ✔✔coronary disease, athlerosclerosis
Why do we give aspirin in pts w/atherosclerosis? - correct answer ✔✔Aspirin is an antiplatelet..
Prevents the existing plaques from getting bigger. Prevents plaque rupture. Cardio protective,
prevents stroke, MI, CVA
What is prescribed for angina pts w/DM? - correct answer ✔✔ACE inhibitors to protect the
kidneys and nerves
SE of high doses of aspirin? - correct answer ✔✔Tinnitus: ringing ears
Pt education regarding Plavix(clopidogrel bisulfate)? - correct answer ✔✔Anti-platelet med. S/sx
bleeding: blood in stool or vomit, excessive bruising, abd pain uterine bld, back pain, petichae.
Interactions with EVERYTHING: OTC, herbals, supplements
Pts on coumadin? What are we watching for? - correct answer ✔✔INR to check therapeutic
levels. Half life is long. Check 12hrs after taking.
What can be caused if pt started on heparin? - correct answer ✔✔day4, ordering blood work to
check platelet count to observe for THROMBOCYTOPENIA
,coumadin and childbearing aged females - correct answer ✔✔Interactions with oral
contraceptives- must have a back up method during time you're taking coumadin
Pregnancy considerations and coumadin - correct answer ✔✔Need to monitor anti-Xa levels
biggest food group interaction with coumadin - correct answer ✔✔Grapefruit, green leafy
veggies. Why? high in vitamin K which counteracts warfarin
Short duration: rapid acting insulin indication, MOA, usage - correct answer ✔✔Given w/meals
Provide bs control between meals at night
Can use in conjunction w/intermediate or long-acting agent
lispro, aspart, gluulocene
Short duration: short acting insulin indication, MOA, usage - correct answer ✔✔Before meals to
control postprandial hyperglycemia
Infused SQ via pump
humulin/regular
intermediate(humalin/novalin) duration insulin indication, MOA, usage - correct answer ✔✔BS
control between meals and during the night
Only one suitable for mixing w/short actings
basal coverage
Long duration: Insulin glargine U100 - correct answer ✔✔up to 24hrs, once daily subq dosing,
basal coverage for DM1 or Dm2
, Neostigmine is a medication uesd to tx what disease/disorder? - correct answer ✔✔Myastenia
Gravis: AI disorder, antibodies destroy communication btw nerves and muscles. S/S weak
skeletal muscles, voluntary muscles, dysphagia, ptosis
Myasthenia gravis is an AI disorder that may cause what s/s? - correct answer ✔✔difficulty
swallowing
Medication must cross _____________ to affect CNS - correct answer ✔✔BBB
Goal in Parkinson's tx is to restore ________________ in brain - correct answer ✔✔dopamine
MCSE of dopaminergics - correct answer ✔✔sleep attacks, hallucinations, confusion
Med appropriate to treat acute psychosis? - correct answer ✔✔Haloperidol
ASE of first-generation antipsychotic(FGA) medications such as haloperidol, chlorpromazine: diff
speaking, chewing - correct answer ✔✔tardive dyskinesia
Med to help manage panic attacks? - correct answer ✔✔SSRI
Cholinesterase inhibitors are used in tx of what conditon? - correct answer ✔✔Alzheimer's
disease. MOA block normal breakdown of acetylocholine which increases their levels and
duration of action in the CNS and PNS (neuromuscular junction). Also used in tx of myasthenia
gravis Ex: neostigmine, donepezil, galantamine, rivastigmine
What are some diseases/disorders/conditions are anticonvulsants used to treat other than
seizure disorders? - correct answer ✔✔migraine HA prevention, bipolar DO, epilepsy Examples:
carbamazepine(Tegretol), gabapentin(Neurontin), phenobarbital, topiramate(Topamax)
