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NURS 663 Exam 1 Study Guide 2026 | 400+ Practice Questions on Bipolar Disorder, Major Depressive Disorder, Psychopharmacology, Antidepressants, Mood Stabilizers & Suicide Risk Assessment

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Prepare confidently for NURS 663 Exam 1 with this comprehensive study guide featuring 400+ exam-style practice questions and expert-verified answer explanations covering the essential concepts of psychiatric mental health nursing, mood disorders, psychopharmacology, psychotherapy, suicide risk assessment, and evidence-based psychiatric treatment. This resource provides an in-depth review of bipolar disorders, major depressive disorder (MDD), persistent depressive disorder (dysthymia), cyclothymia, antidepressant pharmacology, mood stabilizers, electroconvulsive therapy (ECT), cognitive behavioral therapies, and psychiatric diagnostic criteria. Organized in a structured question-and-answer format, this guide is designed to strengthen diagnostic reasoning, reinforce pharmacologic knowledge, and improve examination performance for graduate nursing and psychiatric nurse practitioner students. This study guide comprehensively reviews DSM-5-TR diagnostic criteria for Bipolar I Disorder, Bipolar II Disorder, cyclothymic disorder, persistent depressive disorder, major depressive disorder, mixed episodes, rapid cycling, mania, hypomania, SIGECAPS, Mood Disorder Questionnaire (MDQ), Patient Health Questionnaire-9 (PHQ-9), suicide risk assessment, involuntary commitment criteria, violence risk assessment, delirium, SIADH, monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), bupropion, trazodone, mirtazapine, lithium, valproate (Depakote), carbamazepine, lamotrigine, antidepressant adverse effects, serotonin syndrome, hypertensive crisis, Stevens-Johnson syndrome, lithium toxicity monitoring, therapeutic drug levels, electroconvulsive therapy (ECT), vagus nerve stimulation (VNS), transcranial magnetic stimulation (TMS), cognitive behavioral therapy (CBT), dialectical behavior therapy (DBT), interpersonal therapy (IPT), behavioral therapy, treatment-resistant depression, psychopharmacology dosing principles, laboratory monitoring, medication interactions, and evidence-based management of mood disorders across the lifespan. The realistic practice questions reinforce clinical judgment, differential diagnosis, medication safety, and therapeutic decision-making expected in advanced psychiatric nursing practice. Designed for graduate nursing education and advanced psychiatric practice, this study resource serves as an excellent companion for classroom examinations, PMHNP coursework, clinical practicums, comprehensive reviews, and board certification preparation. The detailed explanations strengthen understanding of psychiatric assessment, evidence-based psychopharmacology, medication management, psychotherapy modalities, and clinical reasoning required to safely evaluate and manage patients with mood disorders and other psychiatric conditions. The content aligns with current psychiatric practice standards and authoritative references, including American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders (DSM-5-TR). American Psychiatric Association Publishing; 2022, Stahl SM. Stahl's Essential Psychopharmacology. 5th ed. Cambridge University Press; 2021, Stahl SM. Prescriber's Guide. 8th ed. Cambridge University Press; 2025, Varcarolis EM. Essentials of Psychiatric Mental Health Nursing. 5th ed. Elsevier; 2024, Sadock BJ, Sadock VA, Ruiz P. Kaplan & Sadock's Synopsis of Psychiatry. 12th ed. Wolters Kluwer; 2021, American Psychiatric Association Practice Guidelines, and the American Nurses Credentialing Center (ANCC) PMHNP Examination Content Outline, providing the scientific and clinical foundation for advanced psychiatric nursing practice. Relevant Students: NURS 663 students, Psychiatric Mental Health Nurse Practitioner (PMHNP) students, Master of Science in Nursing (MSN) students, Doctor of Nursing Practice (DNP) students, Advanced Practice Registered Nurse (APRN) students, Graduate nursing students, Psychiatric nursing students, Mental Health Nursing students, Nurse Practitioner students, Registered Nurse (RN) students, BSN students, Clinical Nurse Specialist (CNS) students, Physician Assistant (PA) students, Medical students, Psychology students, Behavioral Health students, Psychiatry residents, PMHNP certification candidates, ANCC PMHNP exam candidates, Advanced psychopharmacology students. Keywords NURS 663, NURS 663 Exam 1, Psychiatric mental health nursing, PMHNP, Psychopharmacology, Bipolar disorder, Bipolar I disorder, Bipolar II disorder, Cyclothymia, Persistent depressive disorder, Dysthymia, Major depressive disorder, MDD, Mania, Hypomania, Mixed episodes, Rapid cycling, DSM-5-TR, Mood Disorder Questionnaire, MDQ, PHQ-9, SIGECAPS, Suicide risk assessment, Involuntary commitment, MAOI, Monoamine oxidase inhibitors, Tricyclic antidepressants, TCA, SSRI, SNRI, Bupropion, Trazodone, Mirtazapine, Escitalopram, Fluoxetine, Sertraline, Paroxetine, Venlafaxine, Duloxetine, Lithium, Valproate, Carbamazepine, Lamotrigine, Electroconvulsive therapy, ECT, Vagus nerve stimulation, VNS, Transcranial magnetic stimulation, TMS, Cognitive behavioral therapy, CBT, Dialectical behavior therapy, DBT, Interpersonal therapy, Psychiatric assessment, Mood stabilizers, Mental health nursing, Graduate nursing, PMHNP exam preparation

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NURS 663 Exam 1 2026 Expert
Verifed Ace the Test



Bipolar one disorder DSM five criteria - ANSWER ✔✔Manic episode:

1+ week of a colon elevated, expansive or irritable mood and increase

energy. 3+ symptoms from B: distractibility, indiscretion, irresponsible,

grandiosity, flight of ideas, activity(Increase goal-orient), decreased need

for sleep, talkativeness or pressured speech.


Bipolar two DSM five criteria - ANSWER ✔✔Hypo mania and major

depressive disorder: hypo mania same as mania with decreased

severity and duration and no functional impairment for episode of four or

more days and no psychosis

,Mixed episodes (bipolar) - ANSWER ✔✔Manic and depressive

symptoms time by side usually with comorbid substance abuse

increased risk of suicide and psychosis


rapid cycling - ANSWER ✔✔Four or more cycles per year no greater

than a week well period


Cyclothymia DSM-V Criteria - ANSWER ✔✔Two or more years of

mood cycling with dysthymia and hypo mania decreased intensity than

bipolar disorder meets criteria for hypo mania but does not meet criteria

for major depressive disorder


Dysthymia DSM five criteria - ANSWER ✔✔HE'S 2 SAD depressive

symptoms lasting two or more years that is subsydromal characterized

by hopelessness decreased energy, decrease self-esteem for two years,

abnormal sleep, abnormal appetite impaired decision-making.


MAOÍ Mechanism of action generally - ANSWER ✔✔Catalyzes the

deamination of monoamines intracellularly and MAO transport Reuptake

extracellular monoamines


MAO-A Mechanism of action - ANSWER ✔✔MAO-A Oxidizes

serotonin norepinephrine and epinephrine


MAO-B Mechanism of action - ANSWER ✔✔Oxidizes phenylalanine

, MAO-A and MAO-B mechanism of action - ANSWER ✔✔Oxidizes

dopamine non-preferentially


MAOs Neumonic -2 - ANSWER ✔✔Date with Tyra banks with wine

and cheese in Maui— can cause hypertensive crisis related to tyramine

from aged food.




MAWIs= my arms weight increased= effective for atypical depression


MAOs adverse effects-6 - ANSWER ✔✔Hypertensive crisis, diet

restriction, avoid meds, five week after Prozac, two week after other

antidepressants, no other medications for two weeks after discontinuing


MAOs diet restriction-4 compounds - ANSWER ✔✔Tyrosine, high

tyramine, tryptophan, phenylalanine


Tyrosine foods-10 - ANSWER ✔✔Aged cheese, aged wine, fava or

broad bean pods, sauerkraut, soy sauce, tap or draft beer, overripe fruit,

cured meat, spoiled food


MAOs drugs to avoid- 6 - ANSWER ✔✔Antidepressants,

Dextromethorphan, stimulants, sympathomimetics, meperidine,

disulfiram




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