NUR 378 Final Exam V3 | NUR 378
Pharmacology in Nursing | Actual Q&A
with Rationale (NUR378 Final Exam) |
Concordia
1. A nurse is preparing to administer medications to a patient. Which of the following
represent the essential ‘Rights of Medication Administration’ to ensure patient safety?
A. Right Patient
B. Right Medication
C. All of the above
D. Right Route
E. Right Time
F. Right Dose
Correct Answer: C
To prevent medication errors, the nurse must verify the right patient, medication, dose,
route, and time. Verification against the physician’s order and the patient’s record is critical
for clinical safety.
2. When a drug is administered orally and undergoes significant metabolism in the liver
before reaching systemic circulation, this is known as:
A. First-pass effect
,B. Biotransformation
C. Bioavailability
D. Enterohepatic recirculation
Correct Answer: A
The first-pass effect occurs when oral medications are metabolized in the liver after
absorption from the GI tract, reducing the concentration of the active drug before it reaches
the bloodstream.
3. A patient is prescribed a medication with a narrow therapeutic index. Which nursing action
is most appropriate?
A. Monitor serum drug levels frequently
B. Encourage the patient to double the dose if symptoms worsen
C. Administer the drug only as needed
D. Assume the drug has a low risk for toxicity
Correct Answer: A
Drugs with a narrow therapeutic index have a small margin between therapeutic and toxic
doses, requiring close monitoring of serum levels to ensure safety.
4. A patient with hypoalbuminemia is receiving a highly protein-bound medication. The nurse
should monitor for:
A. Increased protein synthesis
, B. Decreased therapeutic effect
C. Rapid drug excretion
D. Signs of drug toxicity
Correct Answer: D
When albumin levels are low, there are fewer binding sites for protein-bound drugs,
leading to more free active drug in the blood and an increased risk of toxicity.
5. The nurse notes that a medication has a half-life of 4 hours. How long will it take for
approximately 94% of the drug to be eliminated from the body?
A. 16 hours
B. 12 hours
C. 8 hours
D. 24 hours
Correct Answer: A
It takes about four half-lives to reach a steady state or to eliminate the majority (93.75%)
of a drug. 4 hours multiplied by 4 half-lives equals 16 hours.
6. An older adult patient is at higher risk for drug toxicity primarily due to which physiological
change?
A. Increased hepatic blood flow
B. Reduced renal excretion
Pharmacology in Nursing | Actual Q&A
with Rationale (NUR378 Final Exam) |
Concordia
1. A nurse is preparing to administer medications to a patient. Which of the following
represent the essential ‘Rights of Medication Administration’ to ensure patient safety?
A. Right Patient
B. Right Medication
C. All of the above
D. Right Route
E. Right Time
F. Right Dose
Correct Answer: C
To prevent medication errors, the nurse must verify the right patient, medication, dose,
route, and time. Verification against the physician’s order and the patient’s record is critical
for clinical safety.
2. When a drug is administered orally and undergoes significant metabolism in the liver
before reaching systemic circulation, this is known as:
A. First-pass effect
,B. Biotransformation
C. Bioavailability
D. Enterohepatic recirculation
Correct Answer: A
The first-pass effect occurs when oral medications are metabolized in the liver after
absorption from the GI tract, reducing the concentration of the active drug before it reaches
the bloodstream.
3. A patient is prescribed a medication with a narrow therapeutic index. Which nursing action
is most appropriate?
A. Monitor serum drug levels frequently
B. Encourage the patient to double the dose if symptoms worsen
C. Administer the drug only as needed
D. Assume the drug has a low risk for toxicity
Correct Answer: A
Drugs with a narrow therapeutic index have a small margin between therapeutic and toxic
doses, requiring close monitoring of serum levels to ensure safety.
4. A patient with hypoalbuminemia is receiving a highly protein-bound medication. The nurse
should monitor for:
A. Increased protein synthesis
, B. Decreased therapeutic effect
C. Rapid drug excretion
D. Signs of drug toxicity
Correct Answer: D
When albumin levels are low, there are fewer binding sites for protein-bound drugs,
leading to more free active drug in the blood and an increased risk of toxicity.
5. The nurse notes that a medication has a half-life of 4 hours. How long will it take for
approximately 94% of the drug to be eliminated from the body?
A. 16 hours
B. 12 hours
C. 8 hours
D. 24 hours
Correct Answer: A
It takes about four half-lives to reach a steady state or to eliminate the majority (93.75%)
of a drug. 4 hours multiplied by 4 half-lives equals 16 hours.
6. An older adult patient is at higher risk for drug toxicity primarily due to which physiological
change?
A. Increased hepatic blood flow
B. Reduced renal excretion
