PH 3407 - L10 (Tissue Repair) Questions with
Correct Answers
What are the four phases of wound healing?
Homeostasis, Inflammatory, Proliferation, Remodeling
What occurs during the homeostasis phase of wound healing?
Vasoconstriction followed by vasodilation, migration of phagocytes, and secretion of growth
factors by platelets.
What is the main goal during the inflammatory phase of wound healing?
To decrease permeability and facilitate tissue recovery.
What are the signs of inflammation during the inflammatory phase?
Erythema, swelling, warmth, and pain.
What role do macrophages play in the inflammatory phase?
They secrete chemotactic and growth factors that stimulate cell migration and tissue matrix
formation.
Neutrophil migration ceases after ____ post injury
Few days
What happens during the proliferation phase of wound healing?
Formation of granulation tissue, epithelialization, and collagen synthesis.
How long can the remodeling phase of wound healing last?
Up to 2 years
, What is the % strength of healing tissue after 4 weeks?
40-70% of the strength of undamaged tissue by 4 weeks.
What is the importance of timing in nutritional interventions during wound healing?
Interventions should align with the healing phase to avoid hindering necessary processes.
What is the role of Vitamin A in tissue repair? 4
- epithelialization
- bone development
- cellular differentiation
- immune function.
What is the recommended dosage of Vitamin A for wound healing? What is the toxicity
limit?
10,000 IU short term; higher doses are considered a drug.
Toxicity at 50,000IU
Vitamin D becomes a drug after ____ IU
2500 IU
Why is zinc important in wound healing? 4
- DNA synthesis
- cell division
- protein synthesis
- tissue regeneration.
What percentage of people in high-income countries are zinc deficient?
Correct Answers
What are the four phases of wound healing?
Homeostasis, Inflammatory, Proliferation, Remodeling
What occurs during the homeostasis phase of wound healing?
Vasoconstriction followed by vasodilation, migration of phagocytes, and secretion of growth
factors by platelets.
What is the main goal during the inflammatory phase of wound healing?
To decrease permeability and facilitate tissue recovery.
What are the signs of inflammation during the inflammatory phase?
Erythema, swelling, warmth, and pain.
What role do macrophages play in the inflammatory phase?
They secrete chemotactic and growth factors that stimulate cell migration and tissue matrix
formation.
Neutrophil migration ceases after ____ post injury
Few days
What happens during the proliferation phase of wound healing?
Formation of granulation tissue, epithelialization, and collagen synthesis.
How long can the remodeling phase of wound healing last?
Up to 2 years
, What is the % strength of healing tissue after 4 weeks?
40-70% of the strength of undamaged tissue by 4 weeks.
What is the importance of timing in nutritional interventions during wound healing?
Interventions should align with the healing phase to avoid hindering necessary processes.
What is the role of Vitamin A in tissue repair? 4
- epithelialization
- bone development
- cellular differentiation
- immune function.
What is the recommended dosage of Vitamin A for wound healing? What is the toxicity
limit?
10,000 IU short term; higher doses are considered a drug.
Toxicity at 50,000IU
Vitamin D becomes a drug after ____ IU
2500 IU
Why is zinc important in wound healing? 4
- DNA synthesis
- cell division
- protein synthesis
- tissue regeneration.
What percentage of people in high-income countries are zinc deficient?
