COMSAE Phase 1 Form 110 Practice
Exam Questions And Correct Answers
(Verified Answers) Plus Rationales 2026
Q&A | Instant Download Pdf
1. What is the primary pacemaker of the heart?
A. Bundle of His
B. AV node
C. Purkinje fibers
D. SA node
Correct: The sinoatrial (SA) node initiates impulses, establishing the
heart rhythm. SA node > AV node > Bundle of His > Purkinje.
2. A patient with chronic pancreatitis is most likely to have which of the
following enzymes elevated?
A. Amylase
B. Lipase
C. ALT
D. ALP
**While both may rise in acute pancreatitis, lipase remains elevated
longer in chronic pancreatitis compared to amylase.
3. The first-line treatment for anaphylaxis is:
A. Diphenhydramine IM
, B. Epinephrine IM
C. IV hydrocortisone
D. Albuterol nebulizer
**Epinephrine intramuscularly is the immediate, life-saving first-line
therapy to reverse airway and vascular effects.
4. Which organ produces erythropoietin?
A. Liver
B. Spleen
C. Kidney
D. Bone marrow
**The kidneys produce erythropoietin (EPO) to stimulate red blood cell
production.
5. A patient with Graves’ disease most likely has which of the following
lab findings?
A. High TSH, high T4
B. Low TSH, low T4
C. Low TSH, high T4
D. High TSH, low T4
**In hyperthyroidism (e.g. Graves’), elevated thyroid hormones
suppress TSH via negative feedback.
6. The most common cause of Cushing’s syndrome is:
A. Adrenal carcinoma
B. Exogenous corticosteroids
C. Pituitary adenoma (Cushing’s disease)
D. Ectopic ACTH secretion
**The most frequent cause of Cushing’s syndrome is long-term use of
glucocorticoids.
7. What is the formula for stroke volume?
A. EDV + ESV
, B. HR × SV
C. EDV − ESV
D. CO / HR
**Stroke volume equals end-diastolic volume minus end-systolic
volume.
8. Which blood gas finding indicates respiratory acidosis?
A. pH 7.50, PaCO₂ 30 mmHg
B. pH 7.25, PaCO₂ 60 mmHg
C. pH 7.55, PaCO₂ 20 mmHg
D. pH 7.35, PaCO₂ 40 mmHg
**Low pH with elevated PaCO₂ reflects respiratory acidosis.
9. Which antibiotic is first-line treatment for syphilis?
A. Benzathine penicillin G
B. Doxycycline
C. Azithromycin
D. Ceftriaxone
**Benzathine penicillin G is the treatment of choice for all stages of
syphilis.
10. In diabetic ketoacidosis (DKA), which electrolyte must be closely
monitored and replaced?
A. Sodium
B. Magnesium
C. Potassium
D. Calcium
**Even if serum potassium appears normal or high, total body K⁺ is
depleted; insulin therapy can rapidly lower K⁺ causing arrhythmias.
11. What is the most common cause of hypothyroidism worldwide?
A. Iodine deficiency
B. Hashimoto’s thyroiditis
Exam Questions And Correct Answers
(Verified Answers) Plus Rationales 2026
Q&A | Instant Download Pdf
1. What is the primary pacemaker of the heart?
A. Bundle of His
B. AV node
C. Purkinje fibers
D. SA node
Correct: The sinoatrial (SA) node initiates impulses, establishing the
heart rhythm. SA node > AV node > Bundle of His > Purkinje.
2. A patient with chronic pancreatitis is most likely to have which of the
following enzymes elevated?
A. Amylase
B. Lipase
C. ALT
D. ALP
**While both may rise in acute pancreatitis, lipase remains elevated
longer in chronic pancreatitis compared to amylase.
3. The first-line treatment for anaphylaxis is:
A. Diphenhydramine IM
, B. Epinephrine IM
C. IV hydrocortisone
D. Albuterol nebulizer
**Epinephrine intramuscularly is the immediate, life-saving first-line
therapy to reverse airway and vascular effects.
4. Which organ produces erythropoietin?
A. Liver
B. Spleen
C. Kidney
D. Bone marrow
**The kidneys produce erythropoietin (EPO) to stimulate red blood cell
production.
5. A patient with Graves’ disease most likely has which of the following
lab findings?
A. High TSH, high T4
B. Low TSH, low T4
C. Low TSH, high T4
D. High TSH, low T4
**In hyperthyroidism (e.g. Graves’), elevated thyroid hormones
suppress TSH via negative feedback.
6. The most common cause of Cushing’s syndrome is:
A. Adrenal carcinoma
B. Exogenous corticosteroids
C. Pituitary adenoma (Cushing’s disease)
D. Ectopic ACTH secretion
**The most frequent cause of Cushing’s syndrome is long-term use of
glucocorticoids.
7. What is the formula for stroke volume?
A. EDV + ESV
, B. HR × SV
C. EDV − ESV
D. CO / HR
**Stroke volume equals end-diastolic volume minus end-systolic
volume.
8. Which blood gas finding indicates respiratory acidosis?
A. pH 7.50, PaCO₂ 30 mmHg
B. pH 7.25, PaCO₂ 60 mmHg
C. pH 7.55, PaCO₂ 20 mmHg
D. pH 7.35, PaCO₂ 40 mmHg
**Low pH with elevated PaCO₂ reflects respiratory acidosis.
9. Which antibiotic is first-line treatment for syphilis?
A. Benzathine penicillin G
B. Doxycycline
C. Azithromycin
D. Ceftriaxone
**Benzathine penicillin G is the treatment of choice for all stages of
syphilis.
10. In diabetic ketoacidosis (DKA), which electrolyte must be closely
monitored and replaced?
A. Sodium
B. Magnesium
C. Potassium
D. Calcium
**Even if serum potassium appears normal or high, total body K⁺ is
depleted; insulin therapy can rapidly lower K⁺ causing arrhythmias.
11. What is the most common cause of hypothyroidism worldwide?
A. Iodine deficiency
B. Hashimoto’s thyroiditis