NR 567 / NR567 Advanced Pharmacology
for the AGACNP
Final Exam Study (Latest )
Chamberlain
Foundations, Cards, Pain, MuscSkel & Rheumatologic
Question:
isoniazid contraindications
Answer:
liver disease
,Question:
TB Treatment Golden Rule
Answer:
TB must always be treated with 2 or more drugs d/t high risk drug
resistant bacilli emerging with monotherapy and decreased incidence of
relapse
Question:
Typically TB Tx Regimen
Answer:
Firstline drugs: isoniazid, rifampin, pyrazinamide, ethambutol
initiation phase 2 months of 4 drugs
continuation phase 4 months of 2 drugs (isoniazid and rifampin)
Question:
Tx of Rifampin-resistant TB
Answer:
can be treated with combination isoniazid, pyrazinamide, and ethambutol
but duration is 18-24 months
,Question:
HIV and TB Considerations (3)
Answer:
treatment can last up to 30 months
rifampin can accelerate metabolism of protease inhibitors and nonucleoside
reverse transcriptase inhibitors
may consider rifabutin instead of rifampin d/t to less acceleration of
metabolism compared to rifampin
Question:
Antihistamine side effects (3)
Answer:
CNS depression at therapeutic levels
paradoxical excitation in overdose and with children
anticholinergic effects d/t weak atropine like antimuscarinic actions
, Question:
phenylephrine (Neosynephrine) and pseudoephedrine (Sudafed) side
effects (3)
Answer:
rebound congestion from topical use > 3-5 days
CV effects: HTN and angina d/t systemic vasoconstriction
CNS stimulation: restlessness, insomnia, anxiety
Question:
Bronchodilators (BAM)
Answer:
Beta 2 agonists (albuterol/salmeterol)
Anticholinergics (ipratropium)
Methylxanthines (theophylline)
for the AGACNP
Final Exam Study (Latest )
Chamberlain
Foundations, Cards, Pain, MuscSkel & Rheumatologic
Question:
isoniazid contraindications
Answer:
liver disease
,Question:
TB Treatment Golden Rule
Answer:
TB must always be treated with 2 or more drugs d/t high risk drug
resistant bacilli emerging with monotherapy and decreased incidence of
relapse
Question:
Typically TB Tx Regimen
Answer:
Firstline drugs: isoniazid, rifampin, pyrazinamide, ethambutol
initiation phase 2 months of 4 drugs
continuation phase 4 months of 2 drugs (isoniazid and rifampin)
Question:
Tx of Rifampin-resistant TB
Answer:
can be treated with combination isoniazid, pyrazinamide, and ethambutol
but duration is 18-24 months
,Question:
HIV and TB Considerations (3)
Answer:
treatment can last up to 30 months
rifampin can accelerate metabolism of protease inhibitors and nonucleoside
reverse transcriptase inhibitors
may consider rifabutin instead of rifampin d/t to less acceleration of
metabolism compared to rifampin
Question:
Antihistamine side effects (3)
Answer:
CNS depression at therapeutic levels
paradoxical excitation in overdose and with children
anticholinergic effects d/t weak atropine like antimuscarinic actions
, Question:
phenylephrine (Neosynephrine) and pseudoephedrine (Sudafed) side
effects (3)
Answer:
rebound congestion from topical use > 3-5 days
CV effects: HTN and angina d/t systemic vasoconstriction
CNS stimulation: restlessness, insomnia, anxiety
Question:
Bronchodilators (BAM)
Answer:
Beta 2 agonists (albuterol/salmeterol)
Anticholinergics (ipratropium)
Methylxanthines (theophylline)
