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Human regular insulin T&P Answer: T: anti diabetic drug, pancreatic hormone
P:short-acting hypoglycemia drug
Human Regular insulin most often used in combination with Answer: intermediate or long
lasting insulin to achieve 24 hour glucose control
Human Regular insulin only insulin that can be given_____ Answer: IV
Human Regular insulin drug interactions Answer: Use cautiously with drugs that can
produce hypoglycemia: sulfonylureas, meglitinides, beta-adrenergic blockers, salicylate,
anabolic steroids, monamine oxidase inhibitors (MAOI's), and alcohol
Drugs that antagonize glucose-lowering effects: dextrothyroxine, corticosteroids,
epinephrine or norepinephrine, furosemide, and thiazide diuretics
ACE inhibitors increase insulin sensitivity and may enhance the hypoglycemic effects of
insulin
Human Regular insulin pregnancy category Answer: Insulin glargine: C
other forms of insulin category B
Human Regular insulin treatment of overdose Answer: Concentrated source of glucose
(dextrose), such as D5W, or glucagon, by the parental route
Glyburide T & P Answer: T: anti diabetic drug
P:sulfonylurea
Glyburide can be used _____ or in combination with another ____ _____ _____ Answer:
alone
oral hypoglycemic drug
List & describe two types of glyburide available Answer: Conventional form (DiaBeta,
Micronase)
Micronized form (Glynase)
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, Glynase allows for lower doses, compared to conventional form.
Glucovance is a combination product that contains glyburide and metformin
Glyburide pregnancy category Answer: C
Glyburide teaching Answer: avoid alcohol, report nausea, vomiting, yellowing of
skin/sclera, abdominal pain, darkening of urine, light color stools
Glyburide treatment of overdose Answer: Concentrated source of glucose
MEtformin T&P Answer: T: Antidiabetic drug
P: biguanide
Metformin indications Answer: Lowers blood glucose levels in type 2 diabetes who are
unable to control glucose levels with diet & exercise
children 10 & over
Metformin describe regular release tablets Answer: Administered once or twice daily,
absorption decreased with food, peak plasma level is 2.5 hours
Metformin describe solution (Riomet) Answer: Administered once or twice daily,
absorption slightly increased with food, peak plasma levels 2.3 hours
Metformin describe sustained release (Fortamet, Glucophage, XR, and Glumetza) Answer:
Extended duration
Administered once daily, absorption significantly increased with food, peak plasma 6-8
hours
Metformin food/herbal Answer: Can cause hypoglycemia
-Ginseng, garlic, black cohosh, juniper berries, fenugreek, coriander, dandelion root
-decreases absorption of vitamin B12 & folic acid
Metformin Pregnancy Answer: C
Metformin teaching Answer: take with food, take at same time each day,
-Approved for 10 years and older
Metformin treatment of overdose Answer: Concentrated source of glucose
Repaglinide T&P Answer: T: anti diabetic drug
P: meglitinide
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