MIMG 185 Final Questions and Answers with Complete Solutions
UPDATED!!!.
Correct
Incorrect
Your answers
1 of 181
Defniton
- two long terminal repeats LTR: transcripton factor binding elementcausing
cellular components to be turned on when binding to it --> virus responds
to stmuli that cell responds to as well
- tat and rev gene: required for replicaton --> transcripton factor
getsstarted, but not fast enough, so tat makes it go 1000x faster --> rev
infuences splicing paterns to have RNA to be in nucleus instead of being
degraded
- Deleton of tat or rev = virus will not replicate and is essentally dead- Vpr
and vpu: accessory proteins needed to grow well in animal model (but not
in vitro)
- nef gene: important - when HIV gets into cell, it has to bind CD4, sonef
downregulates CD4, virus gets in and pulls CD4 down into surface of the
cell (prevents more virus from infectng it) --> also downregulates MHC
molecules MHC A and B, but doesn't downregulate MHC C (HLA) so T cells
won't kill it
,
,
,
UPDATED!!!.
Correct
Incorrect
Your answers
1 of 181
Defniton
- two long terminal repeats LTR: transcripton factor binding elementcausing
cellular components to be turned on when binding to it --> virus responds
to stmuli that cell responds to as well
- tat and rev gene: required for replicaton --> transcripton factor
getsstarted, but not fast enough, so tat makes it go 1000x faster --> rev
infuences splicing paterns to have RNA to be in nucleus instead of being
degraded
- Deleton of tat or rev = virus will not replicate and is essentally dead- Vpr
and vpu: accessory proteins needed to grow well in animal model (but not
in vitro)
- nef gene: important - when HIV gets into cell, it has to bind CD4, sonef
downregulates CD4, virus gets in and pulls CD4 down into surface of the
cell (prevents more virus from infectng it) --> also downregulates MHC
molecules MHC A and B, but doesn't downregulate MHC C (HLA) so T cells
won't kill it
,
,
,
