KATZUNG'S BASIC AND
CLINICAL PHARMACOLOGY
16TH EDITION
• AUTHOR(S)TODD W.
VANDERAH
TEST BANK
,Question 1
A nurse is teaching a community group about the steps
required before a new medication becomes widely available.
Which statement by a participant indicates an accurate
understanding of the process?
A. "A medication can be sold immediately after it is tested in
laboratory animals."
B. "Clinical studies in humans help determine whether a
medication is safe and effective before approval."
C. "Once a medication is approved, no additional safety
monitoring is needed."
D. "Only medications with no adverse effects are approved for
public use."
Correct Answer: B
Rationale:
Clinical studies in humans evaluate safety, effectiveness,
dosage, and adverse effects before a medication receives
regulatory approval. Animal studies alone are insufficient to
establish safety for human use. Ongoing monitoring continues
after approval to identify uncommon or long-term adverse
,effects. No medication is entirely free of risks, so approval is
based on a favorable balance between benefits and risks.
Question 2
A nurse is reviewing informed consent with a client who is
considering enrollment in a clinical drug trial. Which client
statement demonstrates an understanding of informed
consent?
A. "I cannot leave the study once I sign the consent form."
B. "The consent form guarantees that the medication will
improve my condition."
C. "I may withdraw from the study at any time without losing
my routine medical care."
D. "The researchers may change the treatment without
informing me."
Correct Answer: C
Rationale:
Participants have the right to withdraw from a clinical study at
any time without jeopardizing their standard medical care.
Signing informed consent does not obligate continued
participation, guarantee therapeutic benefit, or permit
investigators to change treatments without appropriate
notification and consent.
, Question 3
A nurse is caring for a client who reports using both a
prescription medication and an herbal supplement. What is the
nurse's priority action?
A. Advise the client to discontinue all herbal supplements
immediately.
B. Document only the prescription medication because
supplements are not regulated as drugs.
C. Assess for possible interactions between the prescription
medication and the herbal supplement.
D. Recommend doubling the prescription medication dose if the
herbal supplement is continued.
Correct Answer: C
Rationale:
Many herbal products may interact with prescription
medications, altering therapeutic effects or increasing adverse
events. The nurse should obtain a complete medication history,
including supplements, and assess for potential interactions.
Automatically discontinuing supplements or changing
prescription doses without a provider's direction is
inappropriate.
Question 4
CLINICAL PHARMACOLOGY
16TH EDITION
• AUTHOR(S)TODD W.
VANDERAH
TEST BANK
,Question 1
A nurse is teaching a community group about the steps
required before a new medication becomes widely available.
Which statement by a participant indicates an accurate
understanding of the process?
A. "A medication can be sold immediately after it is tested in
laboratory animals."
B. "Clinical studies in humans help determine whether a
medication is safe and effective before approval."
C. "Once a medication is approved, no additional safety
monitoring is needed."
D. "Only medications with no adverse effects are approved for
public use."
Correct Answer: B
Rationale:
Clinical studies in humans evaluate safety, effectiveness,
dosage, and adverse effects before a medication receives
regulatory approval. Animal studies alone are insufficient to
establish safety for human use. Ongoing monitoring continues
after approval to identify uncommon or long-term adverse
,effects. No medication is entirely free of risks, so approval is
based on a favorable balance between benefits and risks.
Question 2
A nurse is reviewing informed consent with a client who is
considering enrollment in a clinical drug trial. Which client
statement demonstrates an understanding of informed
consent?
A. "I cannot leave the study once I sign the consent form."
B. "The consent form guarantees that the medication will
improve my condition."
C. "I may withdraw from the study at any time without losing
my routine medical care."
D. "The researchers may change the treatment without
informing me."
Correct Answer: C
Rationale:
Participants have the right to withdraw from a clinical study at
any time without jeopardizing their standard medical care.
Signing informed consent does not obligate continued
participation, guarantee therapeutic benefit, or permit
investigators to change treatments without appropriate
notification and consent.
, Question 3
A nurse is caring for a client who reports using both a
prescription medication and an herbal supplement. What is the
nurse's priority action?
A. Advise the client to discontinue all herbal supplements
immediately.
B. Document only the prescription medication because
supplements are not regulated as drugs.
C. Assess for possible interactions between the prescription
medication and the herbal supplement.
D. Recommend doubling the prescription medication dose if the
herbal supplement is continued.
Correct Answer: C
Rationale:
Many herbal products may interact with prescription
medications, altering therapeutic effects or increasing adverse
events. The nurse should obtain a complete medication history,
including supplements, and assess for potential interactions.
Automatically discontinuing supplements or changing
prescription doses without a provider's direction is
inappropriate.
Question 4
