Study Guide (Latest 2026
UPDATED): Advanced
Pharmacology Fundamentals -
Chamberlain
APRN prescribing role - ANSWER ✔✔Prescriptive authority for nurse
practitioners also regulates prescribing rights beyond medications and
controlled substances. These rights include therapeutic devices and
services and are outlined in state practice laws and regulations and
include Durable Medical Equipment (DME) such as wheelchairs, power
scooters, hospital beds, portable oxygen equipment, handicap placards,
etc. and medical services such as Physical Therapy (PT), Occupational
Therapy (OT), home health services, etc. Prescriptive authority
encompasses more than writing a prescription correctly. It requires
,adherence to ethical guidelines to ensure that patients are safeguarded
from harm. Ethical prescribing starts with being well-informed about
medications. Mechanism of action, efficacy, and safety are important
considerations, as are a patient's distinct needs and circumstances,
including the number of medications prescribed (Mitchell & Oliphant,
2016). Most patients receiving a prescription are taking other
medications, whether prescription or over-the-counter. Appropriate
selection, dosing, and duration of pharmaceutical agents are key to
maximizing outcomes and minimizing adverse effects
benefits of full practice authority - ANSWER ✔✔Nurse practitioners
have the autonomy to evaluate patients, diagnose, order and interpret
tests, initiate and manage treatments and prescribe medications,
including controlled substances without physician oversight
promoting positive outcomes through prudent prescribing practices -
ANSWER ✔✔Administering medications and prescribing medications
are two distinct processes. Prescription writing requires prudent and
deliberate decision-making processes to maintain patient safety and
reduce liability, including:
,*documentation of a provider-patient relationship for the recipient of the
prescribed medications
*documentation of a thorough history and physical examination for the
recipient
*documentation of discussions regarding risk factors, side effects, or
therapy options
*documentation of drug monitoring or titration plan, if applicable
*documentation of consultations, if any
avoidance of prescribing medications for self, family, or friends
Rational drug selection requires a logical approach that includes the
formulation of a diagnosis based on clinical reasoning and the selection
and monitoring of the most appropriate pharmacological treatment
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, Considerations include: Cost, guidelines, availability, interactions, side
effects, allergies, hepatic/renal functions, need for monitoring, & special
populations
Beer's Criteria - ANSWER ✔✔identifies drugs with a high likelihood of
causing adverse effects in older adults. Accordingly, drugs on this list
should generally be avoided in adults older than 65 years except when
the benefits are significantly greater than the risks.
Pharmacodynamics - ANSWER ✔✔the study of the biochemical and
physiologic effects of drugs on the body and the molecular mechanisms
by which those effects are produced
Pharmacokinetics - ANSWER ✔✔the study of drug movement
throughout the body
Pharmacogenomics - ANSWER ✔✔the study of how genes affect a
person's response to drugs. The purpose of this is to combine the
sciences of genomics and pharmacology to provide individualized,
targeted, safe drug therapies to patients
CYP450 inducers - ANSWER ✔✔Inducers are xenobiotics
(medications and environmental agents) that elevate CYP450 enzyme
activity by increasing enzyme synthesis. This action leads to additional
sites available for biotransformation. The increased number of sites