FT FT L FT L L
FT L
FT
A nurse working in radiology administers iodine to a patient who is having a computed tomography (CT)
FT L L
FT FT L FT L L
FT FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
scan. The nurse working on the oncology unit administers chemotherapy to patients who have
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
cancer. At the Public Health Department, a nurse administers a measles-mumps-rubella (MMR)
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
vaccine to a 14-month-old child as a routine immunization. Which branch of pharmacology best
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
describes the actions of all three nurses?
FT L FT L FT L FT L FT L FT L FT L
Pharmacoeconomics
FT L Pharmacotherapeutic
s Pharmacodynamics
FT L
FT L Pharmacokinetics
F T L Ans: B
Response:
Pharmacology is the study of the biologic effects of chemicals. Nurses are involved with clinical FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
pharmacology or pharmacotherapeutics, which is a branch of pharmacology that deals with the uses of
FT L L
FT FT L FT L FT L FT L FT L FT L L
FT L
FT FT L FT L FT L L
FT FT L
drugs to treat, prevent, and diagnose disease. The radiology nurse is administering a drug to help
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
diagnose a disease. The oncology nurse is administering a drug to help treat a disease.
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
Pharmacoeconomics includes any costs involved in drug therapy. Pharmacodynamics involves how a FT L FT L FT L FT L FT L FT L L
FT FT L FT L FT L FT L
drug affects the body and pharmacokinetics is how the body acts on the body.
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
A physician has ordered intramuscular (IM) injections of morphine, a narcotic, every 4 hours as needed for
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L L
FT FT L FT L FT L FT L
pain in a motor vehicle accident victim. The nurse is aware this drug has a high abuse potential.
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
Under what category would morphine be classified? L
FT FT L FT L FT L FT L L
FT
Schedule I FT L
FT L Schedule II FT L
FT L Schedule III FT L
FT L Schedule IV FT L
FT L Ans: B
Response:
Narcotics with a high abuse potential are classified as Schedule II drugs because of severe dependence
FT L FT L L
FT FT L L
FT FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
, liability. Schedule I drugs have high abuse potential and no accepted medical use. Schedule III
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
drugs have a lesser abuse potential than II and an accepted medical use. Schedule IV drugs have
L
FT FT L FT L FT L FT L L
FT FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
low abuse potential and limited dependence liability.
FT L FT L FT L FT L FT L FT L FT L
When involved in phase III drug evaluation studies, what responsibilities would the nurse have?
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L L
FT
FT L Working with animals who are given experimental drugs
FT L FT L FT L FT L FT L FT L FT L
Choosing appropriate patients to be involved in the drug study
FT L FT L FT L FT L FT L FT L FT L FT L FT L
FT L Monitoring and observing patients closely for adverse effects
FT L FT L FT L FT L FT L FT L FT L
FT L Conducting research to determine effectiveness of the drug Ans: C
FT L L
FT L
FT FT L FT L L
FT FT L FT L L
FT
Response:
Phase III studies involve use of a drug in a vast clinical population in which patients are asked to
FT L FT L FT L FT L FT L FT L FT L FT L FT L L
FT L
FT FT L FT L FT L FT L FT L FT L FT L
record any symptoms they experience while taking the drugs. Nurses may be responsible for helping
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
collect and analyze the information to be shared with the Food and Drug Administration (FDA) but
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
would not conduct research independently because nurses do not prescribe medications. Use of
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
animals in drug testing is done in the preclinical trials. Select patients who are involved in phase II
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L L
FT FT L FT L FT L FT L FT L FT L
studies to participate in studies where the participants have the disease the drug is intended to treat.
L
FT FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
These patients are monitored closely for drug action and adverse effects. Phase I studies involve
FT L FT L FT L FT L FT L L
FT FT L FT L FT L FT L FT L FT L FT L L
FT FT L
healthy human volunteers who are usually paid for their participation. Nurses may observe for
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
adverse effects and toxicity.
FT L FT L FT L FT L
What concept is considered when generic drugs are substituted for brand name drugs?
FT L FT L L
FT FT L FT L FT L FT L FT L FT L FT L FT L FT L
FT L Bioavailability
Critical concentration L
T
F
FT L Distribution
Half-life
F T L Ans: A
Response:
Bioavailability is the portion of a dose of a drug that reaches the systemic circulation and is available FT L FT L FT L FT L FT L FT L L
FT FT L FT L FT L FT L FT L FT L FT L FT L FT L L
FT
to act on body cells. Binders used in a generic drug may not be the same as those used in the
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
brand name drug. Therefore, the way the body breaks down and uses the drug may differ, which
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
may eliminate a generic drug substitution. Critical concentration is the amount of a drug that is
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
needed to cause a therapeutic effect and should not differ between generic and brand name
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
medications.
FT L
Distribution is the phase of pharmacokinetics, which involves the movement of a drug to the body’s FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
tissues and is the
FT L FT L FT L FT L
, same in generic and brand name drugs. A drug’s half-life is the time it takes for the amount of drug to
FT L L
FT FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L L
FT FT L FT L FT L FT L FT L
decrease to half the peak level, which should not change when substituting a generic medication.
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
A nurse is assessing the patient’s home medication use. After listening to the patient list current
FT L L
FT FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L L
FT
medications, the nurse asks what priority question?
FT L FT L FT L FT L FT L FT L FT L
Do you take any generic medications?
FT L FT L FT L FT L FT L
Are any of these medications orphan drugs?
FT L L
FT FT L FT L FT L FT L
Are these medications safe to take during pregnancy?
FT L L
FT FT L FT L FT L FT L L
FT
FT L Do you take any over-the-counter medications?
FT L FT L FT L FT L FT L
Ans: D
Response:
It is important for the nurse to specifically question use of over-the-counter medications because
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
patients may not consider them important. The patient is unlikely to know the meaning of orphan
FT L FT L FT L FT L FT L L
FT FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
drugs unless they too are health care providers. Safety during pregnancy, use of a generic
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
medication, or classification of orphan drugs are things the patient would be unable to answer but
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
could be found in reference books if the nurse wishes to research them.
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
After completing a course on pharmacology for nurses, what will the nurse know?
L
FT FT L FT L FT L L
FT L
FT FT L FT L FT L FT L FT L FT L
FT L Everything necessary for safe and effective medication administration FT L FT L FT L FT L FT L FT L FT L
Current pharmacologic therapy; the nurse will not require ongoing education for 5 years.
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
FT L General drug information; the nurse can consult a drug guide for specific drug
FT L FT L L
FT FT L FT L L
FT FT L FT L FT L FT L FT L FT L
FT L information. The drug actions that are associated with each classification of medication FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
FT L Ans: C
Response:
After completing a pharmacology course nurses will have general drug information needed for safe
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
and effective medication administration but will need to consult a drug guide for specific drug
L
FT FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
information before administering any medication. Pharmacology is constantly changing, with new
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
drugs entering the market and new uses for existing drugs identified. Continuing education in
FT L FT L F T L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
pharmacology is essential to safe practice. Nurses tend to become familiar with the medications they
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L
administer most often, but there will always be a need to research new drugs and also those the nurse
FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L FT L L
FT FT L FT L FT L FT L FT L
is not familiar with because no nurse knows all medications.
L
FT FT L FT L FT L FT L FT L FT L FT L FT L FT L