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Patients with cystic fibrosis are often prescribed enzyme replacement for
pancreatic secretions. Each replacement drug has lipase, protease, and
amylase components, but the drug is prescribed in units of:
1. Lipase
2. Protease
3. Amylase
4. Pancreatin - DETAILED ANSWER-1. Lipase
Brands of pancreatic enzyme replacement drugs are:
1. Bioequivalent
2. About the same in cost per unit of lipase across brands
3. Able to be interchanged between generic and brand-name products to
reduce cost
4. None of the above - DETAILED ANSWER-2. About the same in cost per unit
of lipase across brands
When given subcutaneously, how long until neutral protamine Hagedorn
insulin begins to take effect (onset of action) after administration?
1. 15 to 30 minutes
2. 60 to 90 minutes
,3. 3 to 4 hours
4. 6 to 8 hours - DETAILED ANSWER-2. 60 to 90 minutes
Both men and women experience bone loss with aging. The bones most
likely to demonstrate significant loss are:
1. Cortical bones
2. Femoral neck bones
3. Cervical vertebrae
4. Pelvic bones - DETAILED ANSWER-2. Femoral neck bones
Bisphosphonates treat or prevent osteoporosis by:
1. Inhibiting osteoclastic activity
2. Fostering bone resorption
3. Enhancing calcium uptake in the bone
4. Strengthening the osteoclastic proton pump - DETAILED ANSWER-1.
Inhibiting osteoclastic activity
Prophylactic use of bisphosphonates is recommended for patients with
early osteopenia related to long-term use of which of the following drugs?
1. Selective estrogen receptor modulators
2. Aspirin
3. Glucocorticoids
4. Calcium supplements - DETAILED ANSWER-3. Glucocorticoids
, Hypoglycemia can result from the action of either insulin or an oral
hypoglycemic. Signs and symptoms of hypoglycemia include:
1. "Fruity" breath odor and rapid respiration
2. Diarrhea, abdominal pain, weight loss, and hypertension
3. Dizziness, confusion, diaphoresis, and tachycardia
4. Easy bruising, palpitations, cardiac dysrhythmias, and coma - DETAILED
ANSWER-3. Dizziness, confusion, diaphoresis, and tachycardia
Nonselective beta blockers and alcohol create serious drug interactions
with insulin because they:
1. Increase blood glucose levels
2. Produce unexplained diaphoresis
3. Interfere with the ability of the body to metabolize glucose
4. Mask the signs and symptoms of altered glucose levels - DETAILED
ANSWER-4. Mask the signs and symptoms of altered glucose levels
Lispro is an insulin analogue produced by recombinant DNA technology.
Which of the following statements about this form of insulin is NOT true?
1. Optimal time of preprandial injection is 15 minutes.
2. Duration of action is increased when the dose is increased.
3. It is compatible with neutral protamine Hagedorn insulin.
4. It has no pronounced peak. - DETAILED ANSWER-2. Duration of action is
increased when the dose is increased.
The decision may be made to switch from twice daily neutral protamine
Hagedorn (NPH) insulin to insulin glargine to improve glycemia control
throughout the day. If this is done: