ACTUAL SCRIPT 2026 COMPLETE QUESTIONS
AND ANSWERS GRADED A+
◉ Phase II Clinical Trial.
Answer: - several hundred of diseased patients
- single-arm, comparative, or selection studies
- "does it work in condition of interest?"
◉ Phase III Clinical Trial.
Answer: - thousands of diseased patients
- large randomized, controlled trials
- compared with standard of care for condition
◉ Phase IV Clinical Trial.
Answer: - post-marketing approval
- evaluates rates of serious side effect
◉ clinical endpoints.
Answer: significant clinical events related to a person's feelings,
function, or survival; can be predicted using surrogate endpoints
,- heart attack
- stroke
- hip fracture
- seizure
◉ surrogate endpoints.
Answer: do not have clinical benefit on their own; used to measure
for predicting clinical endpoints
- BP
- cholesterol level
- bone density
◉ independent/predictor variables.
Answer: the treatments that subjects would be assigned to, and
response will be measured to these variables
◉ one-way hypothesis.
Answer: directional
- "increased/decreased"
- "larger/smaller"
- "greater/lesser"
, ◉ two-way hypothesis.
Answer: does not specify direction
- "different amount"
- "differing results"
◉ null hypothesis (H0).
Answer: no association exists between predictor and the outcome
variable
◉ Type I Statistical Error.
Answer: false positive
◉ Type II Statistical Error.
Answer: false negative
◉ α.
Answer: probability that you will make a Type I Statistical Error
◉ β.
Answer: probability that you will make a Type II Statistical Error
◉ power.