SMU Pharmacology Module 2 Exam Guide – Study Notes, Practice Questions &
Revision
Which of the following describe the action of beta-lactamase? - ANS ✔✔It's an enzyme that
inactivates drugs that have a beta-lactam ring. Can inactivate PCN, cephalosporins, and
carbapenems by cleaving the beta-lactam ring (pg 1024)
The nurse is preparing to administer gentamicin (Apramycin) to a patient when he suddenly
complains of difficulty hearing. What should the nurse do? - ANS ✔✔Nurse should stop
treatment with gentamicin at the first sign of damage (tinnitus and/or persistent headache)
One of the most important factors to consider in the selection of appropriate antibiotic therapy
is? - ANS ✔✔Maximal effect, minimal harm. Need to review type of infecting organism, drug
sensitivity, host factors (site of infxn, immune system). Look for med that has good efficacy, low
toxicity, narrow spectrum. (pg 1025)
An objective symptom of infection is the presence of what? - ANS ✔✔Fever (pg 1032)
When administering the first dose of cefazolin to a patient, the nurse will monitor the patient
closely for a cross-sensitivity reaction if he has an allergy to what? Because your patient is on
aminoglycoside therapy, you as the nurse will assess the patient daily for the presence of what?
- ANS ✔✔Cefazolin - cross sensitivity with penicillin.
Aminoglycosides - nurse will assess for trough levels to minimize ototoxicity and nephrotoxicity
Considering penicillin therapy, what electrolytes should be monitored? - ANS ✔✔Potassium &
sodium (pg 1037)
PCN V should be taken with what? - ANS ✔✔PCN V should be taken with meals (p 1039)
, Why do C&S tests before giving vancomycin? - ANS ✔✔C&S tests will help identify the bacteria
or virus involved in infection. Vancomycin only works against Gram-positive bacteria (eg: S.
aureus, S. epidermidis, streptococci, PCN-resistent pneumococci, and C. diff) (p 1048)
Pyridium is a urinary tract analgesic used to relieve what symptoms? - ANS ✔✔Urinary tract
pain (as from UTI, surgery, catheter insertion)
Multidrug regimens are given for the treatment of HIV infections for what purpose? - ANS
✔✔Since HIV mutates rapidly, the probability of developing resistance to meds is high.
Multidrug regimens minimizes the emergence of resistance (p 1143)
For a patient with herpes simplex encephalitis (a severe brain infection). An expected outcome
after the administration of vidarabine (Vira-A) an antiviral agent is ____? - ANS ✔✔
A nursing intervention associated with immunizations is to? - ANS ✔✔
A patient is to begin isoniazid (INH) orally at 350 mg per day. The nurse should expect to
administer what nutritional supplement and monitor what lab values? - ANS ✔✔Monitor AST
(aspartate aminotransferase) and administer vitamin B6. (p 1090)
A patient may reveal what is in relation to rifampin therapy? - ANS ✔✔
Nitrofurantoin achieves therapeutic concentrations in_____ - ANS ✔✔the lower urinary tract
(bladder + urethra) (p 1085)
Orders read, "penicillin every 8 hours and gentamicin every 12 hours." What would be the best
schedule for the administration of these drugs? - ANS ✔✔0700 (both), 1500 (PCN only), 2300
(PCN only), 0700 (both)
Revision
Which of the following describe the action of beta-lactamase? - ANS ✔✔It's an enzyme that
inactivates drugs that have a beta-lactam ring. Can inactivate PCN, cephalosporins, and
carbapenems by cleaving the beta-lactam ring (pg 1024)
The nurse is preparing to administer gentamicin (Apramycin) to a patient when he suddenly
complains of difficulty hearing. What should the nurse do? - ANS ✔✔Nurse should stop
treatment with gentamicin at the first sign of damage (tinnitus and/or persistent headache)
One of the most important factors to consider in the selection of appropriate antibiotic therapy
is? - ANS ✔✔Maximal effect, minimal harm. Need to review type of infecting organism, drug
sensitivity, host factors (site of infxn, immune system). Look for med that has good efficacy, low
toxicity, narrow spectrum. (pg 1025)
An objective symptom of infection is the presence of what? - ANS ✔✔Fever (pg 1032)
When administering the first dose of cefazolin to a patient, the nurse will monitor the patient
closely for a cross-sensitivity reaction if he has an allergy to what? Because your patient is on
aminoglycoside therapy, you as the nurse will assess the patient daily for the presence of what?
- ANS ✔✔Cefazolin - cross sensitivity with penicillin.
Aminoglycosides - nurse will assess for trough levels to minimize ototoxicity and nephrotoxicity
Considering penicillin therapy, what electrolytes should be monitored? - ANS ✔✔Potassium &
sodium (pg 1037)
PCN V should be taken with what? - ANS ✔✔PCN V should be taken with meals (p 1039)
, Why do C&S tests before giving vancomycin? - ANS ✔✔C&S tests will help identify the bacteria
or virus involved in infection. Vancomycin only works against Gram-positive bacteria (eg: S.
aureus, S. epidermidis, streptococci, PCN-resistent pneumococci, and C. diff) (p 1048)
Pyridium is a urinary tract analgesic used to relieve what symptoms? - ANS ✔✔Urinary tract
pain (as from UTI, surgery, catheter insertion)
Multidrug regimens are given for the treatment of HIV infections for what purpose? - ANS
✔✔Since HIV mutates rapidly, the probability of developing resistance to meds is high.
Multidrug regimens minimizes the emergence of resistance (p 1143)
For a patient with herpes simplex encephalitis (a severe brain infection). An expected outcome
after the administration of vidarabine (Vira-A) an antiviral agent is ____? - ANS ✔✔
A nursing intervention associated with immunizations is to? - ANS ✔✔
A patient is to begin isoniazid (INH) orally at 350 mg per day. The nurse should expect to
administer what nutritional supplement and monitor what lab values? - ANS ✔✔Monitor AST
(aspartate aminotransferase) and administer vitamin B6. (p 1090)
A patient may reveal what is in relation to rifampin therapy? - ANS ✔✔
Nitrofurantoin achieves therapeutic concentrations in_____ - ANS ✔✔the lower urinary tract
(bladder + urethra) (p 1085)
Orders read, "penicillin every 8 hours and gentamicin every 12 hours." What would be the best
schedule for the administration of these drugs? - ANS ✔✔0700 (both), 1500 (PCN only), 2300
(PCN only), 0700 (both)
