HESI EXIT EXAM QUESTIONS AND CORRECT ANSWERS (VERIFIED ANSWERS) PLUS
RATIONALES 2026 Q&A |STUDY GUIDE| INSTANT DOWNLOAD PDF
,*
CORE DOMAINS *
*
Coordinated Care & Leadership *
Safety and Infection Control *
Health Promotion and Maintenance *
Psychosocial Integrity *
Basic Care and Comfort *
Pharmacological Therapies *
,Reduction of Risk Potential *
Physiological Adaptation *
*
INTRODUCTION *
*
This practice assessment is designed to simulate the HESI Exit Exam, a comprehensive licensure preparation
tool for nursing students. The exam evaluates critical clinical knowledge, nursing judgment, and decision-
making skills essential for safe, effective patient care. Questions are primarily multiple-choice with scenario-
based formats that emphasize real-world application. Success requires mastery of foundational theory, applied
professional knowledge, regulatory compliance, ethics, and critical thinking. This study guide provides 100
original questions with verified answers and detailed rationales to strengthen your readiness for licensure. *
*
, SECTION ONE: QUESTIONS 1–100
Question 1
A nurse is caring for a postoperative patient who reports sudden shortness of breath and chest pain. The
patient's oxygen saturation is 88% on room air. Which action should the nurse take first?
A. Administer prescribed anticoagulant medication
B. Elevate the patient's legs
C. Apply supplemental oxygen
D. Notify the provider immediately
🟢 Correct answer: C
🔴 RATIONALE: Supplemental oxygen is the priority intervention to address hypoxia and prevent further
tissue damage. Airway and breathing always come first in the nursing process (ABC framework).
Anticoagulants, leg elevation, and provider notification follow after oxygenation is stabilized.
Question 2
Which medication class is contraindicated in a patient with a history of angioedema?
A. Beta-blockers
B. ACE inhibitors
C. Calcium channel blockers
D. Thiazide diuretics
RATIONALES 2026 Q&A |STUDY GUIDE| INSTANT DOWNLOAD PDF
,*
CORE DOMAINS *
*
Coordinated Care & Leadership *
Safety and Infection Control *
Health Promotion and Maintenance *
Psychosocial Integrity *
Basic Care and Comfort *
Pharmacological Therapies *
,Reduction of Risk Potential *
Physiological Adaptation *
*
INTRODUCTION *
*
This practice assessment is designed to simulate the HESI Exit Exam, a comprehensive licensure preparation
tool for nursing students. The exam evaluates critical clinical knowledge, nursing judgment, and decision-
making skills essential for safe, effective patient care. Questions are primarily multiple-choice with scenario-
based formats that emphasize real-world application. Success requires mastery of foundational theory, applied
professional knowledge, regulatory compliance, ethics, and critical thinking. This study guide provides 100
original questions with verified answers and detailed rationales to strengthen your readiness for licensure. *
*
, SECTION ONE: QUESTIONS 1–100
Question 1
A nurse is caring for a postoperative patient who reports sudden shortness of breath and chest pain. The
patient's oxygen saturation is 88% on room air. Which action should the nurse take first?
A. Administer prescribed anticoagulant medication
B. Elevate the patient's legs
C. Apply supplemental oxygen
D. Notify the provider immediately
🟢 Correct answer: C
🔴 RATIONALE: Supplemental oxygen is the priority intervention to address hypoxia and prevent further
tissue damage. Airway and breathing always come first in the nursing process (ABC framework).
Anticoagulants, leg elevation, and provider notification follow after oxygenation is stabilized.
Question 2
Which medication class is contraindicated in a patient with a history of angioedema?
A. Beta-blockers
B. ACE inhibitors
C. Calcium channel blockers
D. Thiazide diuretics
