ACUTE KIDNEY INJURY REVIEW EXAM UPDATED
QUESTIONS AND ANSWERS SURE A+
✔✔What can urine output be like during the maintenance phase of acute tubular
necrosis - ✔✔The maintenance phase of acute tubular necrosis can be non-oliguric or
oliguric.
✔✔How long does the maintenance phase of acute tubular necrosis usually last -
✔✔The maintenance phase of acute tubular necrosis usually lasts 1-3 weeks but can
last months.
✔✔What treatments may be used during the maintenance phase of acute tubular
necrosis - ✔✔Diuretics and dopamine may be used during the maintenance phase of
acute tubular necrosis.
✔✔What management is important during the maintenance phase of acute tubular
necrosis - ✔✔Electrolyte abnormalities should be treated and volume overload avoided
during the maintenance phase of acute tubular necrosis.
✔✔What occurs during the recovery phase of acute tubular necrosis - ✔✔The recovery
phase of acute tubular necrosis is marked by brisk diuresis and decreasing BUN and
serum creatinine.
, ✔✔What is the mortality associated with intrinsic renal failure - ✔✔Mortality associated
with intrinsic renal failure is 20-50% in hospitalized patients and rises to 70% in ICU
patients on dialysis with additional comorbid illness.
✔✔What is acute interstitial nephritis - ✔✔Acute interstitial nephritis is infiltration of the
tubulointerstitium by granulocytes and macrophages.
✔✔What percentage of intrinsic renal failure cases are caused by acute interstitial
nephritis - ✔✔Acute interstitial nephritis accounts for about 10-15% of intrinsic renal
failure cases.
✔✔What is the most common cause of acute interstitial nephritis - ✔✔Drugs are the
most common cause of acute interstitial nephritis.
✔✔What medications commonly cause acute interstitial nephritis - ✔✔PCNs,
cephalosporins, NSAIDs, PPIs, and sulfa-containing drugs commonly cause acute
interstitial nephritis.
✔✔When can drug-induced acute interstitial nephritis occur - ✔✔Drug-induced acute
interstitial nephritis can occur from 1 day after the first dose to months after several
doses.
✔✔What infections can cause acute interstitial nephritis - ✔✔Streptococcal infection,
histoplasmosis, and Rocky Mountain spotted fever can cause acute interstitial nephritis.
✔✔What immunologic diseases can cause acute interstitial nephritis -
✔✔Glomerulonephritis, Sjogren syndrome, SLE, and sarcoidosis can cause acute
interstitial nephritis.
✔✔What symptoms can occur in acute interstitial nephritis - ✔✔Acute interstitial
nephritis can cause arthralgias, malaise, fever, and maculopapular rash.
✔✔Can acute interstitial nephritis be asymptomatic - ✔✔Some patients with acute
interstitial nephritis are asymptomatic.
✔✔What is the classic triad of acute interstitial nephritis - ✔✔The classic triad of acute
interstitial nephritis is fever, rash, and arthralgia.
✔✔What lab abnormalities are seen in acute interstitial nephritis - ✔✔Acute interstitial
nephritis commonly causes elevated creatinine, elevated BUN and serum creatinine
with a ratio less than 20:1, eosinophilia, and eosinophiluria.
QUESTIONS AND ANSWERS SURE A+
✔✔What can urine output be like during the maintenance phase of acute tubular
necrosis - ✔✔The maintenance phase of acute tubular necrosis can be non-oliguric or
oliguric.
✔✔How long does the maintenance phase of acute tubular necrosis usually last -
✔✔The maintenance phase of acute tubular necrosis usually lasts 1-3 weeks but can
last months.
✔✔What treatments may be used during the maintenance phase of acute tubular
necrosis - ✔✔Diuretics and dopamine may be used during the maintenance phase of
acute tubular necrosis.
✔✔What management is important during the maintenance phase of acute tubular
necrosis - ✔✔Electrolyte abnormalities should be treated and volume overload avoided
during the maintenance phase of acute tubular necrosis.
✔✔What occurs during the recovery phase of acute tubular necrosis - ✔✔The recovery
phase of acute tubular necrosis is marked by brisk diuresis and decreasing BUN and
serum creatinine.
, ✔✔What is the mortality associated with intrinsic renal failure - ✔✔Mortality associated
with intrinsic renal failure is 20-50% in hospitalized patients and rises to 70% in ICU
patients on dialysis with additional comorbid illness.
✔✔What is acute interstitial nephritis - ✔✔Acute interstitial nephritis is infiltration of the
tubulointerstitium by granulocytes and macrophages.
✔✔What percentage of intrinsic renal failure cases are caused by acute interstitial
nephritis - ✔✔Acute interstitial nephritis accounts for about 10-15% of intrinsic renal
failure cases.
✔✔What is the most common cause of acute interstitial nephritis - ✔✔Drugs are the
most common cause of acute interstitial nephritis.
✔✔What medications commonly cause acute interstitial nephritis - ✔✔PCNs,
cephalosporins, NSAIDs, PPIs, and sulfa-containing drugs commonly cause acute
interstitial nephritis.
✔✔When can drug-induced acute interstitial nephritis occur - ✔✔Drug-induced acute
interstitial nephritis can occur from 1 day after the first dose to months after several
doses.
✔✔What infections can cause acute interstitial nephritis - ✔✔Streptococcal infection,
histoplasmosis, and Rocky Mountain spotted fever can cause acute interstitial nephritis.
✔✔What immunologic diseases can cause acute interstitial nephritis -
✔✔Glomerulonephritis, Sjogren syndrome, SLE, and sarcoidosis can cause acute
interstitial nephritis.
✔✔What symptoms can occur in acute interstitial nephritis - ✔✔Acute interstitial
nephritis can cause arthralgias, malaise, fever, and maculopapular rash.
✔✔Can acute interstitial nephritis be asymptomatic - ✔✔Some patients with acute
interstitial nephritis are asymptomatic.
✔✔What is the classic triad of acute interstitial nephritis - ✔✔The classic triad of acute
interstitial nephritis is fever, rash, and arthralgia.
✔✔What lab abnormalities are seen in acute interstitial nephritis - ✔✔Acute interstitial
nephritis commonly causes elevated creatinine, elevated BUN and serum creatinine
with a ratio less than 20:1, eosinophilia, and eosinophiluria.
