UTMB ADVANCED PATHOPHYSIOLOGY
5355 MODULE 6.2 PULMONARY FINAL
SCRIPT 2026 COMPLETE QUESTIONS AND
ANSWERS PASSED A+
◉ Cardiac repolarization.
Answer: resting state of heart, ventricles relaxed
◉ cardiac depolarization.
Answer: Depolarization occurs in the four chambers of the heart:
both atria first, and then both ventricles- cardiac contraction
◉ Atherosclerosis.
Answer: Atherosclerosis is an inflammatory disease that begins with
endothelial injury and progresses through several stages to become
a fibrotic plaque. Once a plaque has formed it can rupture, resulting
in thrombosis and vasoconstriction that leads to obstruction of the
lumen and inadequate perfusion of distal tissues
◉ fatty streak.
Answer: macrophages filled with fat
, ◉ fibrous plaque.
Answer: is an intimal aggregation of lipids, blood proteins and
inflammatory cells
◉ Plaque development.
Answer: 1. Injury to endothelium
2. Free radicals oxidize LDL cholesterol producing foam cells which
accumulate in the vessel wall,
3. Oxidized LDL triggers an inflammatory response (an indirect
measure of inflammation related to atherosclerotic plaque is the C-
reactive protein level)
4. Smooth muscle in the vessel lumen hypertrophies causing fibrous
scar tissue and restriction of blood flow,
5. Platelets adhere to the irregular surface of plaque, forming clots
6. Fibrous plaques calcify
7. Plaque extends to obstruct the vessel or will break off and travel
◉ complicated plaque.
Answer: A ruptured plaque that has thrombus formation
◉ atherogenesis.
Answer: formation of fatty plaque on the wall of an artery
5355 MODULE 6.2 PULMONARY FINAL
SCRIPT 2026 COMPLETE QUESTIONS AND
ANSWERS PASSED A+
◉ Cardiac repolarization.
Answer: resting state of heart, ventricles relaxed
◉ cardiac depolarization.
Answer: Depolarization occurs in the four chambers of the heart:
both atria first, and then both ventricles- cardiac contraction
◉ Atherosclerosis.
Answer: Atherosclerosis is an inflammatory disease that begins with
endothelial injury and progresses through several stages to become
a fibrotic plaque. Once a plaque has formed it can rupture, resulting
in thrombosis and vasoconstriction that leads to obstruction of the
lumen and inadequate perfusion of distal tissues
◉ fatty streak.
Answer: macrophages filled with fat
, ◉ fibrous plaque.
Answer: is an intimal aggregation of lipids, blood proteins and
inflammatory cells
◉ Plaque development.
Answer: 1. Injury to endothelium
2. Free radicals oxidize LDL cholesterol producing foam cells which
accumulate in the vessel wall,
3. Oxidized LDL triggers an inflammatory response (an indirect
measure of inflammation related to atherosclerotic plaque is the C-
reactive protein level)
4. Smooth muscle in the vessel lumen hypertrophies causing fibrous
scar tissue and restriction of blood flow,
5. Platelets adhere to the irregular surface of plaque, forming clots
6. Fibrous plaques calcify
7. Plaque extends to obstruct the vessel or will break off and travel
◉ complicated plaque.
Answer: A ruptured plaque that has thrombus formation
◉ atherogenesis.
Answer: formation of fatty plaque on the wall of an artery
