ADME QUIZ WITH COMPLETE
SOLUTIONS
What is the primary organ for excretion?
A) Kidney
B) Liver
C) Small Intestine
D) Stomach - Correct Answers -A) Kidney
Of ADME, which deals with molecules moving out of the plasma and into the tissues?
A) Absorption
B) Distribution
C) Metabolism
D) Excretion - Correct Answers -B) Distribution
Which drug is NOT poorly absorbed?
A) Azithromycin
B) Furosemide
C) Digoxin
D) Iraconazole - Correct Answers -A) AZ
Can a drug be effective when there is no measurable drug concentration in the blood? -
Correct Answers -Yes
-Eye drops
-Drugs that are not found in high concentrations in blood, but still effective
If Drug A's Effective Dose is 50 mg and Lethal Dose is 100 mg, what is the Therapeutic
Index?
A) 4
B) 2
C) 0.5
D) 1 - Correct Answers -B) 2
When plasma concentration is increased, will absorption will decrease or increase?
A) Increase
B) Decrease - Correct Answers -B) Decrease
How can you correct for an increase in plasma concentration?
A) Increase Dose
B) Stop Dose
C) Lower Dose
SOLUTIONS
What is the primary organ for excretion?
A) Kidney
B) Liver
C) Small Intestine
D) Stomach - Correct Answers -A) Kidney
Of ADME, which deals with molecules moving out of the plasma and into the tissues?
A) Absorption
B) Distribution
C) Metabolism
D) Excretion - Correct Answers -B) Distribution
Which drug is NOT poorly absorbed?
A) Azithromycin
B) Furosemide
C) Digoxin
D) Iraconazole - Correct Answers -A) AZ
Can a drug be effective when there is no measurable drug concentration in the blood? -
Correct Answers -Yes
-Eye drops
-Drugs that are not found in high concentrations in blood, but still effective
If Drug A's Effective Dose is 50 mg and Lethal Dose is 100 mg, what is the Therapeutic
Index?
A) 4
B) 2
C) 0.5
D) 1 - Correct Answers -B) 2
When plasma concentration is increased, will absorption will decrease or increase?
A) Increase
B) Decrease - Correct Answers -B) Decrease
How can you correct for an increase in plasma concentration?
A) Increase Dose
B) Stop Dose
C) Lower Dose
