h b6 h h h h h
ationales for Nursing Practice 13th Edition (Vers
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ion 2024/2025) Geralyn Frandsen
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, GRADESBOOST.COM
Chapter 1, The Foundation of Pharmacology: Quality and Safety
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1. A woman diagnosed with obsessive–compulsive disorder has been prescribed oral
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h paroxetine hydrochloride. What is the expected effect for this prescription?
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A. Curative effect on symptoms h h h
B. Systemic effect on symptoms h h h
C. Local effect on symptoms h h h
D. Parenteral effect on symptoms h h h
ANS: B h h
Rationale: Drugs that produce systemic effects are taken into the body, circulated through the
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bloodstream to their sites of action in various body tissues, and eventually eliminated from
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the body. Curative agents are given to cure a disease process. In this case, paroxeti ne
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hydrochloride will control the symptoms but not cure the disorder. Drugs with local eff ects,
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such as sunscreen and local anesthetics, act mainly at the site of application. Paroxet ine
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hydrochloride is not administered parenterally. Parenteral agents are administered sub
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cutaneously, intramuscularly, or intravenously.
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PTS: 1 REF: p. 3, Introduction OBJ: 1 h h
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
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es TOP:
h Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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hKEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understandh h NOT: Multiple Choice h h h h h
2. A client has been prescribed an antibiotic. This medication is a naturally occurring
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substance that has been cheG
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alDlyEm
SoBdOifOieSd.TW
.hCaOt Mi s another name for this type o
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f medication?
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A. Synthetic drug
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B. Semisynthetic drug
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C. Biotechnology drug h
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D. Prototype drug
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ANS: B
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Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances
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that have been chemically modified. Synthetic drugs are more standardized in their chemic al
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characteristics, more consistent in their effects, and less likely to produce allergic react ions.
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Biotechnology drugs involve manipulating DNA and RNA and recombining genes i nto
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hybrid molecules that can be inserted into living organisms. Prototype drugs are the f irst
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drug of a particular group to be developed.
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PTS: 1 REF: p. 3, Drug Sources OBJ: 1 h h h
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
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es TOP:
h Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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hKEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understandh h NOT: Multiple Choice h h h h h
3. Which classification applies to morphine?
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A. Central nervous system depressant h h h
B. Central nervous system stimulant h h h
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, GRADESBOOST.COM
C. Anti-inflammatory
D. Antihypertensive
ANS: A h h
Rationale: Drugs are classified according to their effects on particular body systems, their
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therapeutic uses, and their chemical characteristics. Morphine is classified as a central ne
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rvous system depressant and will produce this effect in the client. A central nervous syste m
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stimulant increases attention and raises mood. An anti-
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inflammatory agent decreases inflammation at the site of tissue or joint inflammation. An h h h h h h h h h h h h
antihypertensive agent reduces blood pressure.
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PTS: 1 REF:
p. 3, Drug Classifications and Prototypes OBJ: 1 h h h h h h
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
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es TOP:
h Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Remember NOT: Multiple Choice
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4. A client is administered amoxicillin. The generic name of this medication belongs to whi ch
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drug group?
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A. Selective serotonin reuptake inhibitors h h h
B. Diuretics
C. Penicillins
D. ACE inhibitors h
ANS: C h h
Rationale: The generic namGeRoAfD
teE
n SinBdO
icO
atS
esTt.hC
eOdrug group (e.g., drugs with generic nam es
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ending in ―cillin‖ are penicillins). Selective serotonin reuptake inhibitors are medicatio
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ns that have antidepressant effects; SSRI is a broad classification, not a generic name. Diur
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etics are medications that increase urine output; diuretic is a broad classification, not a ge
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neric name. ACE inhibitor is the broad classification for the angiotensin receptor blockers,
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not the generic name.
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PTS: 1 REF: p. 3, Drug Names OBJ: 2
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NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
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es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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hKEY: Integrated Process: Nursing Process h h h h
BLM: Cognitive Level: Understand NOT: Multiple Choice
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5. The administration of diphenhydramine is regulated by which U.S. government agency?
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A. Public Health Service h h
B. Federal Trade Commission h h
C. Occupational Safety and Health Administration h h h h
D. Food and h
h Drug Administration ANS: D b6 h
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, GRADESBOOST.COM
Rationale: The Food and Drug Administration approves drugs for over-the-
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counter availability, including the transfer of drugs from prescription to OTC status, and may
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require clinical trials to determine the safety and effectiveness of OTC use. The Pu blic
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hHealth Service is regulated by the state to maintain the health of individual citizens of
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the state. The Federal Trade Commission regulates imports and exports throughout the
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nation. The Occupational Safety and Health Administration regulates safety within the wo
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rkplace.
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PTS: 1 REF:
p. 4, Prescription and Nonprescription Drugs OBJ: 4
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NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
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es TOP:
h h Chapter: 1: The Foundation of Pharmacology: Quality and Safety h h h h h h h h
KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand
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6. In the U.S., the administration of anabolic steroids is regulated by which law?
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A. The Food, Drug, and Cosmetic Act of 1938
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B. The Comprehensive Drug Abuse Prevention and Control Act
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C. The Harrison Narcotic Act h h h
D. The Sherley Amendment h h
ANS: B h h
Rationale: The Comprehensive Drug Abuse Prevention and Control Act regulates the ma
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nufacture and distribution of narcotics, stimulants, depressants, hallucinogens, and anaboli
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hc steroids. The Food, Drug, and Cosmetic Act of 1938 revised and broadened FDA
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powe rs and responsibilities, giving the FDA control over drug safety. The Harrison Narcotic
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Ac t restricted the importation, manufacture, sale, and use of opium, cocaine, marijuana,
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and other drugs that the act defiGn eRd Aa Ds E
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erley Amendment of 1912
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prohibited fraudulent claims of drug effectiveness.
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PTS: 1 REF:
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p. 4, Prescription and Nonprescription Drugs OBJ: 3
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NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
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es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Remember
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7. A nurse is responsible for maintaining an accurate count and record of the controlled
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substances on the nursing division. This nursing action is regulated by which U.S. law or
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agency?
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A. The Food, Drug, and Cosmetic Act of 1938
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B. The Public Health Service h h h
C. The Drug Enforcement Administration
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D. The Sherley Amendment h h
h ANS: C h
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