TEST BANK FOR Cellular and Molecular Immunology 10th Edition by Abul K. Abbas, Andrew H. Lichtman ISBN:978-0323757485 COMPLETE GUIDE ALL CHAPTERS COVERED 100 % VERIFIED A+ GRADE ASSURED !!!!! NEW LATEST UPDATE !!!!!

10th Edition
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,Table of Contents
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Chapter 01 Properties and Overview of Immune Responses
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Chapter 02 Cells and Tissues of the Immune System
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Chapter 03 Leukocyte Circulation and Migration Into Tissues
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Chapter 04 Innate Immunity
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Chapter 05 Antibodies and Antigens
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Chapter 06 Antigen Presentation to T Lymphocytes and the Functions of Major
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Histocompatibility Complex Molecules
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Chapter 07 Immune Receptors and Signal Transduction
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Chapter 08 Lymphocyte Development and Antigen Receptor Gene Rearrangement
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Chapter 09 Activation of T Lymphocytes
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Chapter 10 Differentiation and Functions of CD4+ Effector T Cells
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Chapter 11 Differentiation and Functions of CD8+ Effector T Cells
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Chapter 12 B Cell Activation and Antibody Production
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Chapter 13 Effector Mechanisms of Humoral Immunity
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Chapter 14 Specialized Immunity at Epithelial Barriers and in Immune Privileged Tissues
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Chapter 15 Immunologic Tolerance and Autoimmunity
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Chapter 16 Immunity to Microbes
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Chapter 17 Transplantation Immunology
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Chapter 18 Tumor Immunology
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Chapter 19 Hypersensitivity Disorders
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Chapter 20 Allergy
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Chapter 21 Primary and Acquired Immunodeficiencies
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,Chapter 01: Properties and Overview of Immune Responses
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Abbas, Lichtman, and Pillai: Cellular and Molecular Immunology, 10th Edition
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MULTIPLE CHOICE tg




1. The principal function of the immune system is:
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a. Defense against cancer tg tg



b. Repair of injured tissues tg tg tg



c. Defense against microbial infections tg tg tg



d. Prevention of inflammatory diseases tg tg tg



e. Protection against environmental toxins tg tg tg




ANS: C
The immune system has evolved in the setting of selective pressures imposed by microbi al
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infections. Although immune responses to cancer may occur, the concept that “immun osurv
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eillance” against cancer is a principal function of the immune system is controversi al. Repai
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r of injured tissues may be a secondary consequence of the immune responses a nd inflamm
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ation. Although the immune system has regulatory features that are needed to prevent excessi
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ve inflammation, prevention of inflammatory diseases is not a primary fu nction. The immun
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e system can protect against microbial toxins, but it generally does not offer protection again
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st toxins of nonbiologic origin.
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2. Which of the following infectious diseases was prevented by the first successf ul
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vaccination?
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a. Polio
b. Tuberculosis
c. Smallpox
d. Tetanus
e. Rubella
ANS: C
In 1798, Edward Jenner reported the first intentional successful vaccination, which was a gai
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nst smallpox in a boy, using material from the cowpox pustules of a milkmaid. In 1980
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, smallpox was reported to be eradicated worldwide by a vaccination program. Effective vac
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cines against tetanus toxin, rubella virus, and poliovirus were developed in the 20th c entury
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and are widely used. There is no effective vaccine against Mycobacterium tuberc ulosis.
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3. Which of the following is a unique property of the adaptive immune system?
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a. Highly diverse repertoire of specificities for antigens tg tg tg tg tg tg



b. Self-nonself discrimination tg



c. Recognition of microbial structures by both cell-associated and soluble receptors tg tg tg tg tg tg tg tg tg



d. Protection against viral infections tg tg tg



e. Responses that have the same kinetics and magnitude on repeated exposure to t he tg tg tg tg tg tg tg tg tg tg tg tg tg



same microbe tg tg




ANS: A

, Highly diverse repertoires of specificities for antigens are found only in T and B lympho cyte
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s, which are the central cellular components of the adaptive immune system. Both th e in
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nate and the adaptive immune systems use cell-
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associated and soluble receptors to recognize microbes, display some degree of self-
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nonself discrimination, and protect against viruses. On repeated exposure to the same mi cro
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be, the adaptive immune response becomes more rapid and of greater magnitude; this is th
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e manifestation of memory.
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4. Antibodies and T lymphocytes are the respective mediators of which two types of
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immunity?
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a. Innate and adaptive tg tg



b. Passive and active tg tg



c. Specific and nonspecific tg tg



d. Humoral and cell-mediated tg tg



e. Adult and neonatal tg tg




ANS: D
Both B and T lymphocytes are principal components of adaptive immunity. B lymphocyt
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e s produce antibodies, which are the recognition and effector molecules of humoral imm
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un e responses to extracellular pathogens. T cells recognize and promote eradication of intrac
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ellular pathogens in cell- tg tg tg



mediated immunity. Passive and active immunity both can be mediated by either B or T ly m
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phocytes. Specific immunity is another term for adaptive immunity. Both B and T lymp hocy
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tes participate in adult adaptive immunity but are still developing in the neonatal peri od.
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5. The two major functional classes of effector T lymphocytes are:
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a. Helper T lymphocytes and cytotoxic T lymphocytes tg tg tg tg tg tg




b. Natural killer cells and cytoWtoWxW
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c. Memory T cells and effector T cells tg tg tg tg tg tg



d. Helper cells and antigen-presenting cells tg tg tg tg



e. Cytotoxic T lymphocytes and target cells tg tg tg tg tg




ANS: A
T cells can be classified into effector subsets that perform different effector functions. Mo st
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effector T cells are either helper T lymphocytes, which enhance the responses of other immu
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ne cells, including phagocytes and B cells, to infections, or cytotoxic T lymphocyt es, whic
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h directly kill infected cells. Natural killer cells are not T lymphocytes.
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Antigen-presenting cells usually are not T cells. Memory T cells are not effector T cells. tg tg tg tg tg tg tg tg tg tg tg tg tg tg




6. Which of the following cell types is required for all adaptive humoral immune responses?
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a. Natural killer cells tg tg



b. Dendritic cells tg



c. Cytolytic T lymphocytes tg tg



d. B lymphocytes tg



e. Helper T lymphocytes tg tg




ANS: D
Humoral immune responses are antibody- tg tg tg tg



mediated immune responses, and all antibodies are made by B lymphocytes and no oth er
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cell type. tg