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ANSWERS GRADED A+ (2026)
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gram positive bacteria - answer-staph
strep
enterococcus
- everything else is gram negative
penicillins - answer-MOA: inhibit bacterial wall synthesis by binding to and activating
enzymes that are essential for cell wall function
effective against gram positive bacteria
- strep throat
- ear infections
- syphillis
cephalosporins - answer-MOA: inhibit cell wall synthesis
broad spectrum, effective against pos and neg bacteria, later generations are more
effective against gram neg
treat respiratory infections, UTIs, skin infections, bacterial meningitis, pneumonia
cephalosporin generations - answer-1 - cephalexin
2 - cefuroxime
3 - ceftriaxone
,4 - cefepime
macrolides - answer-MOA: inhibit bacterial protein synthesis
effective against primarily gram pos but some gram neg
erythromycin, azithromycin, clarithromycin
treat respiratory infections, bronchitis, pna, skin infections, STIs
flouroquinolones - answer-MOA: inhibit bacterial DNA synthesis
broad spectrum +/-
ciprofloxacin, levofloxacin, moxifloxacin
UTIs, GI infections, respiratory infections, skin infections
Risk of tendon rupture! Last resort abx
tetracyclines - answer-MOA: inhibit bacterial synthesis
broad spectrum +/-
tetracycline, doxycycline, minocycline
acne, respiratory infections, lyme, rocky mountain spotted fever, STIs
,don't use in kids <8 y.o. unless RMSF
aminoglycosides - answer-MOA: inhibit bacterial protein synthesis
gram negative bacteria
tobramicin, gentamicin, amikacin
treat sepsis, pna, UTIs, often in combo with another med
risk of ototoxicity, nephrotoxicity, neuromuscular blockade
sulfonamides - answer-MOA: inhibits synthesis of folic acid in bacteria
gram + and some gram neg
bactrim, sulfamethoxazole
UTIs, ear infections, PNA
Live attenuated vaccines - answer-MMR, varicella, nasal flu, rotavirus, yellow fever,
smallpox
can cause fever and rash - normal!
must be given on the same day or at least 4 weeks apart, too close together can
interfere with effectiveness
AVOID in pregnancy and immunocompromised
, do not give before 1 year old
When do you start giving flu vaccine? - answer-6 months old
Do you vaccinate if the child is ill or febrile? - answer-Yes
kawasaki disease - answer-acute inflammatory condition that affects kids <5 y.o,
inflammation of blood vessels, can lead to heart problems
s/s:
fever >5 days
conjunctivitis
strawberry tongue
cracked lips, erythema in oral cavity
rash
edema and erythema of hands, feet
peeling fingertips
cervical lymphadenopathy
irritability
Tx: IVIG 2g/kg and high dose aspirin
Refer to Cardiology
diagnostic criteria of kawasakis - answer-5 days of fever plus 4 of the following:
- bilateral conjunctival injection
- polymorphic rash
- cervical lymphadenopathy