CPJE 2026 Practice Exam | Realistic
Questions & Answers New Update
Comprehensive Scenario Based
Practice Questions & Explanations
Rotigotine - ✔✔ANSWER ✔✔-Neupro patch: do not
heat/ use during MRI
,HLA b1502 - ✔✔ANSWER ✔✔-Test in Asians. Rash
for carbamazepine (tegretol), phenytoin (Dilantin),
fos phenytoin (cerebyx)
Trastuzumab - ✔✔ANSWER ✔✔-Herceptin,
her/Neu- ado-trastuzunab (kadcyla), lapatinib
(tykerb) pertuzumab (perjeta)
Hla- b 5701 - ✔✔ANSWER ✔✔-Don't give abacavir
(ziagen), epzicom, trizivir
Not cross reactive a/ opioid allergy - ✔✔ANSWER
✔✔-Fentanyl, meperidine (Demerol), methadone
(dolophine), tramadol (ultram), tapentadol
(nucynta)
,Inducers - ✔✔ANSWER ✔✔-Ps porcs (phenytoin,
smoking, phenobarbital, oxcarbazepine, rifampin,
carbamazepine, St. John's wort)
Inhibitors - ✔✔ANSWER ✔✔-Gpacman (grapefruit,
pi's, azoles, cimetidine/cyclosporine, macrolides-
erytho/clarithro, amiodarone, non dihydro (dilt,
verapamil)
If on amiodarone, decrease these drugs by 30-50% -
✔✔ANSWER ✔✔-Digoxin, warfarin, quinidine,
procainanide, statins
Statins with high risk of inhibition - ✔✔ANSWER
✔✔-Las (lova, atorva, simva)
Entecavir - ✔✔ANSWER ✔✔-Baraclude. Empty
stomach for hep B that fail lamivudime and
adefovir- se: peripheral edema, nephrotoxic
, Ribavirin - ✔✔ANSWER ✔✔-Copegus. W/ food bid
for hep c, hepatotoxic, hemolytic anemia, preg x,
psych disorders, ci: renal disfxn
Glipizide - ✔✔ANSWER ✔✔-Glucotrol 30 min
before break & dinner
Glimeprimide - ✔✔ANSWER ✔✔-Amaryl 1-2 mg qd
w/ 1st meal
Glyburide - ✔✔ANSWER ✔✔-Diabeta, + metformin
= glucovance, do not use w/ renal failure 2.5-5mg
qd
Rosiglitazone - ✔✔ANSWER ✔✔-Avandia 4-8mg qd
(tzd, exacerbate hf, liver damage, increases hdl,
decreases tg/total cholesterol) similar: pioglitazone
(actos)
Questions & Answers New Update
Comprehensive Scenario Based
Practice Questions & Explanations
Rotigotine - ✔✔ANSWER ✔✔-Neupro patch: do not
heat/ use during MRI
,HLA b1502 - ✔✔ANSWER ✔✔-Test in Asians. Rash
for carbamazepine (tegretol), phenytoin (Dilantin),
fos phenytoin (cerebyx)
Trastuzumab - ✔✔ANSWER ✔✔-Herceptin,
her/Neu- ado-trastuzunab (kadcyla), lapatinib
(tykerb) pertuzumab (perjeta)
Hla- b 5701 - ✔✔ANSWER ✔✔-Don't give abacavir
(ziagen), epzicom, trizivir
Not cross reactive a/ opioid allergy - ✔✔ANSWER
✔✔-Fentanyl, meperidine (Demerol), methadone
(dolophine), tramadol (ultram), tapentadol
(nucynta)
,Inducers - ✔✔ANSWER ✔✔-Ps porcs (phenytoin,
smoking, phenobarbital, oxcarbazepine, rifampin,
carbamazepine, St. John's wort)
Inhibitors - ✔✔ANSWER ✔✔-Gpacman (grapefruit,
pi's, azoles, cimetidine/cyclosporine, macrolides-
erytho/clarithro, amiodarone, non dihydro (dilt,
verapamil)
If on amiodarone, decrease these drugs by 30-50% -
✔✔ANSWER ✔✔-Digoxin, warfarin, quinidine,
procainanide, statins
Statins with high risk of inhibition - ✔✔ANSWER
✔✔-Las (lova, atorva, simva)
Entecavir - ✔✔ANSWER ✔✔-Baraclude. Empty
stomach for hep B that fail lamivudime and
adefovir- se: peripheral edema, nephrotoxic
, Ribavirin - ✔✔ANSWER ✔✔-Copegus. W/ food bid
for hep c, hepatotoxic, hemolytic anemia, preg x,
psych disorders, ci: renal disfxn
Glipizide - ✔✔ANSWER ✔✔-Glucotrol 30 min
before break & dinner
Glimeprimide - ✔✔ANSWER ✔✔-Amaryl 1-2 mg qd
w/ 1st meal
Glyburide - ✔✔ANSWER ✔✔-Diabeta, + metformin
= glucovance, do not use w/ renal failure 2.5-5mg
qd
Rosiglitazone - ✔✔ANSWER ✔✔-Avandia 4-8mg qd
(tzd, exacerbate hf, liver damage, increases hdl,
decreases tg/total cholesterol) similar: pioglitazone
(actos)
