, TESTBANK FOR Stevens's Clinical Immunology A Laboratory Perspective
6th Edition Miller
Important Notes
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,Chapter 1 Introduction to Immunity and the Immune System
Multiple Choice
Identify the choice that best completes the statement or answers the question.
1. Attenuation can take place through ______ a pathogen.
A. freezing
B. growing
C. aging
D. flooding
ANS: C
PTS: 1
OBJ: 1
MSC: Taxonomy 1
2. The scientist known for his use of attenuated vaccines and as the father of immunology is:
A. Edward Jenner.
B. Elie Metchnikoff.
C. Louis Pasteur.
D. Emil von Behring.
ANS: C
PTS: 1
OBJ: 2
MSC: Taxonomy 1
3. The field of immunology can be credited for its contributions to the development of:
A. bacterial identification.
B. vaccines.
C. surgery.
D. phlebotomy.
ANS: B
PTS: 1
OBJ: 2
MSC: Taxonomy 1
4. The ancient practice of inhaling powder from smallpox scabs is an early version of:
A. innate immunity.
B. vaccination.
C. susceptibility.
Copyright © 2026 by F.A. Davis Company
p. 1
All rights reserved. This material is protected by copyright. No part of it may be reproduced, stored in a retrieval
system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or other-
wise, without written permission from the publisher. Use of this content outside your academic institution is ex-
pressly prohibited and enforceable by law.
, D. cell identification.
ANS: B
PTS: 1
OBJ: 2
MSC: Taxonomy 2
5. Humoral immunity was considered the most important aspect of immunity for a time in history
because of the work of _____________, who received the Nobel Prize in Physiology for his
work in serum therapy.
A. Louis Pasteur
B. Emil von Behring
C. Almroth Wright
D. Edward Jenner
ANS: B
PTS: 1
OBJ: 3
MSC: Taxonomy 1
6. The discovery of _______ helped bring the importance of cellular immunity to light.
A. antibodies
B. phagocytosis
C. opsonins
D. bacterial toxin neutralization by serum
ANS: B
PTS: 1
OBJ: 3
MSC: Taxonomy 2
7. Phagocytosis is appropriately categorized into which of the following?
A. Adaptive immunity
B. Innate immunity
C. Humoral immunity
D. Specific immunity
ANS: B
PTS: 1
OBJ: 3
MSC: Taxonomy 2
8. Maturation and differentiation of important immune cells happen within the:
A. blood.
B. bone marrow.
Copyright © 2026 by F.A. Davis Company
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system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or other-
wise, without written permission from the publisher. Use of this content outside your academic institution is ex-
pressly prohibited and enforceable by law.
, C. lymph nodes.
D. spleen.
ANS: B
PTS: 1
OBJ: 4
MSC: Taxonomy 1
9. Which of the following cells can phagocytize foreign microbes?
A. T lymphocytes
B. B lymphocytes
C. Macrophages
D. Natural killer (NK) cells
ANS: C
PTS: 1
OBJ: 5
MSC: Taxonomy 1
10. Which of the following cells is a phagocytic cell that has a similar morphology to nerve cells?
A. Neutrophils
B. Dendritic cells
C. Mast cells
D. Macrophages
ANS: B
PTS: 1
OBJ: 5 & 6
MSC: Taxonomy 1
11. Macrophages play a key role in adaptive immunity through which function?
A. Phagocytosis
B. Anti-tumor activity
C. Presenting phagocytosed microbes to T lymphocytes
D. Microbial killing
ANS: C
PTS: 1
OBJ: 6
MSC: Taxonomy 2
12. Which granulocytic cell, most known for its role in allergic reactions, contains serine proteases,
heparin, and histamine?
A. Basophil
B. Macrophage
Copyright © 2026 by F.A. Davis Company
p. 3
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system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or other-
wise, without written permission from the publisher. Use of this content outside your academic institution is ex-
pressly prohibited and enforceable by law.
, C. Eosinophil
D. Mast cell
ANS: D
PTS: 1
OBJ: 6
MSC: Taxonomy 1
13. A patient with a weakened immune response may need to have which primary lymphoid tissue
examined?
A. Spleen
B. Mucosal-associated lymphoid tissue (MALT)
C. Thymus
D. Lymph nodes
ANS: C
PTS: 1
OBJ: 7 & 8
MSC: Taxonomy 3
14. Lymphocytes come in contact with foreign antigens and activate the adaptive immune system in
which lymphoid tissue?
A. Bone marrow
B. Peripheral blood
C. Thymus
D. Skin-associated lymphoid tissue (SALT)
ANS: D
PTS: 1
OBJ: 7 & 8
MSC: Taxonomy 3
15. Which lymphoid tissue can protect us against pathogens we eat?
A. Mucosal-associated lymphoid tissue (MALT)
B. Skin-associated lymphoid tissue (SALT)
C. Lymph nodes
D. Spleen
ANS: A
PTS: 1
OBJ: 8
MSC: Taxonomy 3
16. Secondary lymphoid tissues that are located throughout the human body and serve as a collecting
duct for lymph fluid are:
Copyright © 2026 by F.A. Davis Company
p. 4
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system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or other-
wise, without written permission from the publisher. Use of this content outside your academic institution is ex-
pressly prohibited and enforceable by law.
, A. spleen cells.
B. lymph nodes.
C. mucosal-associated lymphoid tissue (MALT).
D. skin-associated lymphoid tissue (SALT).
ANS: B
PTS: 1
OBJ: 8 & 9
MSC: Taxonomy 1
17. Foreign microbes that enter through a cut in our hand should expect defense from which lym-
phoid tissue?
A. Skin-associated lymphoid tissue (SALT)
B. Spleen
C. Mucosal-associated lymphoid tissue (MALT)
D. Thymus
ANS: A
PTS: 1
OBJ: 8
MSC: Taxonomy 3
18. Macrophages line the _______ found within the lymph nodes.
A. outer cortex
B. inner medulla
C. paracortex
D. sinuses
ANS: D
PTS: 1
OBJ: 9
MSC: Taxonomy 1
19. B cells activate and generate B-cell memory in the _____ of the lymph nodes.
A. sinuses
B. secondary follicles
C. paracortex
D. primary follicles
ANS: B
PTS: 1
OBJ: 9
MSC: Taxonomy 2
20. Antigen presentation by dendritic cells to T cells happens within the ______of the lymph nodes.
Copyright © 2026 by F.A. Davis Company
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system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or other-
wise, without written permission from the publisher. Use of this content outside your academic institution is ex-
pressly prohibited and enforceable by law.
, A. primary follicles
B. secondary follicles
C. paracortex
D. sinuses
ANS: C
PTS: 1
OBJ: 9
MSC: Taxonomy 2
21. We can identify lymphocyte populations by proteins found on their cell surfaces. These are
known as:
A. adhesion molecules.
B. antibodies.
C. chemotaxins.
D. clusters of differentiation.
ANS: D
PTS: 1
OBJ: 10
MSC: Taxonomy 1
22. Which CD marker is found on B lymphocytes?
A. CD4
B. CD20
C. CD8
D. CD3
ANS: B
PTS: 1
OBJ: 10
MSC: Taxonomy 1
23. A patient with a viral infection that has stimulated their cell-mediated immunity might have an
increased number of which type of leukocytes in their peripheral blood?
A. Lymphocytes
B. Neutrophils
C. Monocytes
D. Basophils
ANS: A
PTS: 1
OBJ: 11
MSC: Taxonomy 3
Copyright © 2026 by F.A. Davis Company
p. 6
All rights reserved. This material is protected by copyright. No part of it may be reproduced, stored in a retrieval
system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or other-
wise, without written permission from the publisher. Use of this content outside your academic institution is ex-
pressly prohibited and enforceable by law.
,24. A patient with antibodies in their serum to a particular virus has activated which immune cells?
A. Natural killer (NK) cells
B. Macrophages
C. B lymphocytes
D. T lymphocytes
ANS: C
PTS: 1
OBJ: 11
MSC: Taxonomy 3
25. Humoral immunity is a key function of which cell?
A. Natural killer (NK) cells
B. T lymphocytes
C. Macrophages
D. B lymphocytes
ANS: D
PTS: 1
OBJ: 11
MSC: Taxonomy 2
26. Which lymphocyte is part of our innate immunity?
A. CD4 cells
B. CD8 cells
C. CD19 cells
D. Natural killer (NK) cells
ANS: D
PTS: 1
OBJ: 10, 11
MSC: Taxonomy 2
27. Our first line of defense against virally infected cells and tumor cells are:
A. B lymphocytes.
B. T lymphocytes.
C. neutrophils.
D. Natural killer (NK) cells.
ANS: D
PTS: 1
OBJ: 11
MSC: Taxonomy 1
Copyright © 2026 by F.A. Davis Company
p. 7
All rights reserved. This material is protected by copyright. No part of it may be reproduced, stored in a retrieval
system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or other-
wise, without written permission from the publisher. Use of this content outside your academic institution is ex-
pressly prohibited and enforceable by law.
, Chapter 2 Innate Immunity
Multiple Choice
Identify the choice that best completes the statement or answers the question.
1. Which of the following innate immune mechanisms is not part of the anatomical barriers that
keep microorganisms from entering the body?
A. Keratin coating epithelial cells
B. Lactic acid in sweat
C. Surfactant in mucosal secretions
D. Phagocytosis
ANS: D
PTS: 1
OBJ: 1 & 3
MSC: Taxonomy 1
2. A pathogen killed by defensins was defeated by which of the following defense mechanisms?
A. Specialized barriers, adaptive immunity
B. Specialized barriers, innate immunity
C. Cell receptors, adaptive immunity
D. Cell receptors, innate immunity
ANS: B
PTS: 1
OBJ: 1 & 2
MSC: Taxonomy 3
3. Which best describes the process of a neutrophil recognizing zymosan and engulfing a pathogen?
A. An adaptive immune response to a gram-negative bacterial invasion
B. An innate immune response to a yeast invasion
C. An innate immune response to a gram-negative bacterial invasion
D. An adaptive immune response to a gram-positive bacterial invasion
ANS: B
PTS: 1
OBJ: 2 & 7
MSC: Taxonomy 3
Copyright © 2026 by F.A. Davis Company
p. 1
All rights reserved. This material is protected by copyright. No part of it may be reproduced, stored in a retrieval
system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or other-
wise, without written permission from the publisher. Use of this content outside your academic institution is ex-
pressly prohibited and enforceable by law.
6th Edition Miller
Important Notes
The file includes the complete test bank, organized chapter by chapter.
A sample of selected pages has been provided for preview.
All available appendices and Excel files (if included in the original resources) are
provided.
We continuously update our files to ensure you receive the latest and most accurate
editions.
New editions are added regularly – stay connected for updates!
⚠️Note on Answer Keys: If the answer key is not included within the chapter
questions, you will find the complete answers and solutions at the end of each
chapter.
✅ Why Buy From Us?
📚 Complete & organized chapter-by-chapter – no missing content, no guessing.
⚡ Instant digital delivery – get your file the moment you pay, no waiting.
📅 Always up to date – we track new editions so you always get the latest version.
💬 Friendly support – real humans ready to help, anytime you need us.
🔒 Safe & secure – thousands of satisfied students trust us every semester.
🛡️Our Guarantees
💰 Money-Back Guarantee: Not satisfied? We offer a full refund – no questions asked.
🔄 Wrong File? No Problem: Contact us and we will replace it immediately with the
correct version, free of charge.
⏰ 24/7 Support: We are always here – reach out anytime and expect a fast response.
Contact Email:
,Chapter 1 Introduction to Immunity and the Immune System
Multiple Choice
Identify the choice that best completes the statement or answers the question.
1. Attenuation can take place through ______ a pathogen.
A. freezing
B. growing
C. aging
D. flooding
ANS: C
PTS: 1
OBJ: 1
MSC: Taxonomy 1
2. The scientist known for his use of attenuated vaccines and as the father of immunology is:
A. Edward Jenner.
B. Elie Metchnikoff.
C. Louis Pasteur.
D. Emil von Behring.
ANS: C
PTS: 1
OBJ: 2
MSC: Taxonomy 1
3. The field of immunology can be credited for its contributions to the development of:
A. bacterial identification.
B. vaccines.
C. surgery.
D. phlebotomy.
ANS: B
PTS: 1
OBJ: 2
MSC: Taxonomy 1
4. The ancient practice of inhaling powder from smallpox scabs is an early version of:
A. innate immunity.
B. vaccination.
C. susceptibility.
Copyright © 2026 by F.A. Davis Company
p. 1
All rights reserved. This material is protected by copyright. No part of it may be reproduced, stored in a retrieval
system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or other-
wise, without written permission from the publisher. Use of this content outside your academic institution is ex-
pressly prohibited and enforceable by law.
, D. cell identification.
ANS: B
PTS: 1
OBJ: 2
MSC: Taxonomy 2
5. Humoral immunity was considered the most important aspect of immunity for a time in history
because of the work of _____________, who received the Nobel Prize in Physiology for his
work in serum therapy.
A. Louis Pasteur
B. Emil von Behring
C. Almroth Wright
D. Edward Jenner
ANS: B
PTS: 1
OBJ: 3
MSC: Taxonomy 1
6. The discovery of _______ helped bring the importance of cellular immunity to light.
A. antibodies
B. phagocytosis
C. opsonins
D. bacterial toxin neutralization by serum
ANS: B
PTS: 1
OBJ: 3
MSC: Taxonomy 2
7. Phagocytosis is appropriately categorized into which of the following?
A. Adaptive immunity
B. Innate immunity
C. Humoral immunity
D. Specific immunity
ANS: B
PTS: 1
OBJ: 3
MSC: Taxonomy 2
8. Maturation and differentiation of important immune cells happen within the:
A. blood.
B. bone marrow.
Copyright © 2026 by F.A. Davis Company
p. 2
All rights reserved. This material is protected by copyright. No part of it may be reproduced, stored in a retrieval
system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or other-
wise, without written permission from the publisher. Use of this content outside your academic institution is ex-
pressly prohibited and enforceable by law.
, C. lymph nodes.
D. spleen.
ANS: B
PTS: 1
OBJ: 4
MSC: Taxonomy 1
9. Which of the following cells can phagocytize foreign microbes?
A. T lymphocytes
B. B lymphocytes
C. Macrophages
D. Natural killer (NK) cells
ANS: C
PTS: 1
OBJ: 5
MSC: Taxonomy 1
10. Which of the following cells is a phagocytic cell that has a similar morphology to nerve cells?
A. Neutrophils
B. Dendritic cells
C. Mast cells
D. Macrophages
ANS: B
PTS: 1
OBJ: 5 & 6
MSC: Taxonomy 1
11. Macrophages play a key role in adaptive immunity through which function?
A. Phagocytosis
B. Anti-tumor activity
C. Presenting phagocytosed microbes to T lymphocytes
D. Microbial killing
ANS: C
PTS: 1
OBJ: 6
MSC: Taxonomy 2
12. Which granulocytic cell, most known for its role in allergic reactions, contains serine proteases,
heparin, and histamine?
A. Basophil
B. Macrophage
Copyright © 2026 by F.A. Davis Company
p. 3
All rights reserved. This material is protected by copyright. No part of it may be reproduced, stored in a retrieval
system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or other-
wise, without written permission from the publisher. Use of this content outside your academic institution is ex-
pressly prohibited and enforceable by law.
, C. Eosinophil
D. Mast cell
ANS: D
PTS: 1
OBJ: 6
MSC: Taxonomy 1
13. A patient with a weakened immune response may need to have which primary lymphoid tissue
examined?
A. Spleen
B. Mucosal-associated lymphoid tissue (MALT)
C. Thymus
D. Lymph nodes
ANS: C
PTS: 1
OBJ: 7 & 8
MSC: Taxonomy 3
14. Lymphocytes come in contact with foreign antigens and activate the adaptive immune system in
which lymphoid tissue?
A. Bone marrow
B. Peripheral blood
C. Thymus
D. Skin-associated lymphoid tissue (SALT)
ANS: D
PTS: 1
OBJ: 7 & 8
MSC: Taxonomy 3
15. Which lymphoid tissue can protect us against pathogens we eat?
A. Mucosal-associated lymphoid tissue (MALT)
B. Skin-associated lymphoid tissue (SALT)
C. Lymph nodes
D. Spleen
ANS: A
PTS: 1
OBJ: 8
MSC: Taxonomy 3
16. Secondary lymphoid tissues that are located throughout the human body and serve as a collecting
duct for lymph fluid are:
Copyright © 2026 by F.A. Davis Company
p. 4
All rights reserved. This material is protected by copyright. No part of it may be reproduced, stored in a retrieval
system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or other-
wise, without written permission from the publisher. Use of this content outside your academic institution is ex-
pressly prohibited and enforceable by law.
, A. spleen cells.
B. lymph nodes.
C. mucosal-associated lymphoid tissue (MALT).
D. skin-associated lymphoid tissue (SALT).
ANS: B
PTS: 1
OBJ: 8 & 9
MSC: Taxonomy 1
17. Foreign microbes that enter through a cut in our hand should expect defense from which lym-
phoid tissue?
A. Skin-associated lymphoid tissue (SALT)
B. Spleen
C. Mucosal-associated lymphoid tissue (MALT)
D. Thymus
ANS: A
PTS: 1
OBJ: 8
MSC: Taxonomy 3
18. Macrophages line the _______ found within the lymph nodes.
A. outer cortex
B. inner medulla
C. paracortex
D. sinuses
ANS: D
PTS: 1
OBJ: 9
MSC: Taxonomy 1
19. B cells activate and generate B-cell memory in the _____ of the lymph nodes.
A. sinuses
B. secondary follicles
C. paracortex
D. primary follicles
ANS: B
PTS: 1
OBJ: 9
MSC: Taxonomy 2
20. Antigen presentation by dendritic cells to T cells happens within the ______of the lymph nodes.
Copyright © 2026 by F.A. Davis Company
p. 5
All rights reserved. This material is protected by copyright. No part of it may be reproduced, stored in a retrieval
system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or other-
wise, without written permission from the publisher. Use of this content outside your academic institution is ex-
pressly prohibited and enforceable by law.
, A. primary follicles
B. secondary follicles
C. paracortex
D. sinuses
ANS: C
PTS: 1
OBJ: 9
MSC: Taxonomy 2
21. We can identify lymphocyte populations by proteins found on their cell surfaces. These are
known as:
A. adhesion molecules.
B. antibodies.
C. chemotaxins.
D. clusters of differentiation.
ANS: D
PTS: 1
OBJ: 10
MSC: Taxonomy 1
22. Which CD marker is found on B lymphocytes?
A. CD4
B. CD20
C. CD8
D. CD3
ANS: B
PTS: 1
OBJ: 10
MSC: Taxonomy 1
23. A patient with a viral infection that has stimulated their cell-mediated immunity might have an
increased number of which type of leukocytes in their peripheral blood?
A. Lymphocytes
B. Neutrophils
C. Monocytes
D. Basophils
ANS: A
PTS: 1
OBJ: 11
MSC: Taxonomy 3
Copyright © 2026 by F.A. Davis Company
p. 6
All rights reserved. This material is protected by copyright. No part of it may be reproduced, stored in a retrieval
system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or other-
wise, without written permission from the publisher. Use of this content outside your academic institution is ex-
pressly prohibited and enforceable by law.
,24. A patient with antibodies in their serum to a particular virus has activated which immune cells?
A. Natural killer (NK) cells
B. Macrophages
C. B lymphocytes
D. T lymphocytes
ANS: C
PTS: 1
OBJ: 11
MSC: Taxonomy 3
25. Humoral immunity is a key function of which cell?
A. Natural killer (NK) cells
B. T lymphocytes
C. Macrophages
D. B lymphocytes
ANS: D
PTS: 1
OBJ: 11
MSC: Taxonomy 2
26. Which lymphocyte is part of our innate immunity?
A. CD4 cells
B. CD8 cells
C. CD19 cells
D. Natural killer (NK) cells
ANS: D
PTS: 1
OBJ: 10, 11
MSC: Taxonomy 2
27. Our first line of defense against virally infected cells and tumor cells are:
A. B lymphocytes.
B. T lymphocytes.
C. neutrophils.
D. Natural killer (NK) cells.
ANS: D
PTS: 1
OBJ: 11
MSC: Taxonomy 1
Copyright © 2026 by F.A. Davis Company
p. 7
All rights reserved. This material is protected by copyright. No part of it may be reproduced, stored in a retrieval
system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or other-
wise, without written permission from the publisher. Use of this content outside your academic institution is ex-
pressly prohibited and enforceable by law.
, Chapter 2 Innate Immunity
Multiple Choice
Identify the choice that best completes the statement or answers the question.
1. Which of the following innate immune mechanisms is not part of the anatomical barriers that
keep microorganisms from entering the body?
A. Keratin coating epithelial cells
B. Lactic acid in sweat
C. Surfactant in mucosal secretions
D. Phagocytosis
ANS: D
PTS: 1
OBJ: 1 & 3
MSC: Taxonomy 1
2. A pathogen killed by defensins was defeated by which of the following defense mechanisms?
A. Specialized barriers, adaptive immunity
B. Specialized barriers, innate immunity
C. Cell receptors, adaptive immunity
D. Cell receptors, innate immunity
ANS: B
PTS: 1
OBJ: 1 & 2
MSC: Taxonomy 3
3. Which best describes the process of a neutrophil recognizing zymosan and engulfing a pathogen?
A. An adaptive immune response to a gram-negative bacterial invasion
B. An innate immune response to a yeast invasion
C. An innate immune response to a gram-negative bacterial invasion
D. An adaptive immune response to a gram-positive bacterial invasion
ANS: B
PTS: 1
OBJ: 2 & 7
MSC: Taxonomy 3
Copyright © 2026 by F.A. Davis Company
p. 1
All rights reserved. This material is protected by copyright. No part of it may be reproduced, stored in a retrieval
system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or other-
wise, without written permission from the publisher. Use of this content outside your academic institution is ex-
pressly prohibited and enforceable by law.
