EVOLVE PHARMACOLOGY HESI PRACTICE
ALREADY GRADED A+ 2026
A client who has been taking phenazopyridine (Pyridium) 𝑓or symptoms
o𝑓 urethritis and cystitis comes to the clinic because her urine is
reddish-orange. Which question should the practical nurse ask to
determine i𝑓 the medication has been e𝑓𝑓ective? A) How much water
have you been drinking each day?
B)Does the urine color stain your toilet bowl or undergarments?
C)Have you had any relie𝑓 𝑓rom urinary pain, burning, or urgency?
D)Did your urine appear cloudy or have a 𝑓oul odor on voiding? -ANSWER-
C) Have you had any relie𝑓 𝑓rom urinary pain, burning, or urgency?
Feedback:
Phenazopyridine, an over-the-counter urinary analgesic, acts on the
mucosa o𝑓 the urinary tract to relieve urinary pain, burning, itching, or
urgency (C) associated with urethritis and cystitis. Although determining i 𝑓
the client is 𝑓orcing 𝑓luids (A), experiencing staining 𝑓rom Pyridium's side
e𝑓𝑓ect (B), or having signs o𝑓 a urinary in𝑓ection (D) are worthwhile
assessments, the therapeutic response o𝑓 Pyridium is related to urinary
discom𝑓orts only.
A male client who has been receiving an antineoplastic drug has
developed thrombocytopenia. What instructions should the
practical nurse (PN) rein𝑓orce? A) Use suppository 𝑓orm o𝑓 drugs.
B)Avoid large public gatherings.
C)Rise slowly when standing up.
D)Shave with an electric razor. -ANSWER-D) Shave with an electric razor.
Feedback:
Thrombocytopenia is a common side e𝑓𝑓ect o𝑓 bone marrow depression
caused by several antineoplastic agents. The client is experiencing a low
platelet count and should use an electric razor (D) to reduce his risk
o𝑓
,bleeding. (A, B, and C) are not indicated 𝑓or a client who
needs to thrombocytopenia precautions.
implement
The practical nurse (PN) is caring 𝑓or a client who has been taking
prednisone (Deltasone) daily 𝑓or a year. Which adverse e 𝑓𝑓ect should
the PN document in the client's record? A) Photosensitvity.
B)Weight gain.
C)Loss o𝑓 hair.
D)Pale skin color. -ANSWER-B) Weight gain.
Feedback:
Long term use o𝑓 prednisone causes 𝑓luid retention and redistribution
o𝑓 𝑓at deposition. Weight gain (B) and moon 𝑓ace re𝑓lect adverse
e𝑓𝑓ects o𝑓 long-term prednisone use and should be documented. (A, C,
and D) do not occur with treatment using prednisone.
A 𝑓emale client with recurring headaches tells the practical nurse (PN)
that she has been taking at least 4 grams o𝑓 acetaminophen a day. Which
laboratory studies should the PN review 𝑓or this client?
A)Creatinine clearance.
B)Hepatic enzymes.
C)Coagulation values.
D)Arterial blood gases. -ANSWER-B) Hepatic enzymes.
Feedback:
Liver toxicity can occur when doses o𝑓 acetaminophen exceed 4 grams a
day, resulting in an elevation in hepatic enzyme values (B). (A, C, and D)
do not reveal 𝑓indings related to acetaminophen toxicity.
A client receives a prescription 𝑓or an oral opioid analgesic 𝑓or post-
operative pain. Which adverse e𝑓𝑓ect should the practical nurse (PN)
monitor 𝑓or with the client? A) Constipation.
B)Photosensitivity.
C)Decreased heart rate.
, D)Frequent urination. -ANSWER-A) Constipation.
Feedback:
Opioid analgesics slow peristalsis, which leads to constipation (A), a
common side e𝑓𝑓ect o𝑓 opiates. (B, C, and D) are not associated with
opioid analgesics.
Which action should the practical nurse implement when administering a
buccal medication?
A)Encourage the client to swallow.
B)Administer water with medication.
C)Ensure the medication is positioned under the tongue.
D)Place the medication between the upper molar teeth and cheek. -
ANSWER-D) Place the medication between the upper molar teeth and
cheek.
Feedback:
Buccal medications are placed between the upper molar teeth and the
cheek (D) 𝑓or absorption by the capillaries o𝑓 the oral mucosa. The client
should be cautioned against swallowing, not (A). Buccal medications are
not administered with water (B). (C) describes sublingual administration.
What assessment is most important 𝑓or the practical nurse (PN) to
obtain prior to initiating medication therapy with phenelzine (Nardil) 𝑓or
a client with depression? A) Activity level.
B)Mood and a𝑓𝑓ect.
C)Understanding o𝑓 diet modi𝑓ication.
D)The client's support system. -ANSWER-C) Understanding o𝑓 diet
modi𝑓ication.
Feedback:
To prevent a potentially lethal hypertensive crisis, a tyramine- 𝑓ree diet
should be maintained during antidepressant therapy with Nardil, a
monoamine oxidase inhibitor (MAOI). It is most important to determine i 𝑓
the client understands diet modi𝑓ication (C) be𝑓ore Nardil is initiated to
prevent consumption o𝑓 𝑓oods that interact with Nardil. Although a
ALREADY GRADED A+ 2026
A client who has been taking phenazopyridine (Pyridium) 𝑓or symptoms
o𝑓 urethritis and cystitis comes to the clinic because her urine is
reddish-orange. Which question should the practical nurse ask to
determine i𝑓 the medication has been e𝑓𝑓ective? A) How much water
have you been drinking each day?
B)Does the urine color stain your toilet bowl or undergarments?
C)Have you had any relie𝑓 𝑓rom urinary pain, burning, or urgency?
D)Did your urine appear cloudy or have a 𝑓oul odor on voiding? -ANSWER-
C) Have you had any relie𝑓 𝑓rom urinary pain, burning, or urgency?
Feedback:
Phenazopyridine, an over-the-counter urinary analgesic, acts on the
mucosa o𝑓 the urinary tract to relieve urinary pain, burning, itching, or
urgency (C) associated with urethritis and cystitis. Although determining i 𝑓
the client is 𝑓orcing 𝑓luids (A), experiencing staining 𝑓rom Pyridium's side
e𝑓𝑓ect (B), or having signs o𝑓 a urinary in𝑓ection (D) are worthwhile
assessments, the therapeutic response o𝑓 Pyridium is related to urinary
discom𝑓orts only.
A male client who has been receiving an antineoplastic drug has
developed thrombocytopenia. What instructions should the
practical nurse (PN) rein𝑓orce? A) Use suppository 𝑓orm o𝑓 drugs.
B)Avoid large public gatherings.
C)Rise slowly when standing up.
D)Shave with an electric razor. -ANSWER-D) Shave with an electric razor.
Feedback:
Thrombocytopenia is a common side e𝑓𝑓ect o𝑓 bone marrow depression
caused by several antineoplastic agents. The client is experiencing a low
platelet count and should use an electric razor (D) to reduce his risk
o𝑓
,bleeding. (A, B, and C) are not indicated 𝑓or a client who
needs to thrombocytopenia precautions.
implement
The practical nurse (PN) is caring 𝑓or a client who has been taking
prednisone (Deltasone) daily 𝑓or a year. Which adverse e 𝑓𝑓ect should
the PN document in the client's record? A) Photosensitvity.
B)Weight gain.
C)Loss o𝑓 hair.
D)Pale skin color. -ANSWER-B) Weight gain.
Feedback:
Long term use o𝑓 prednisone causes 𝑓luid retention and redistribution
o𝑓 𝑓at deposition. Weight gain (B) and moon 𝑓ace re𝑓lect adverse
e𝑓𝑓ects o𝑓 long-term prednisone use and should be documented. (A, C,
and D) do not occur with treatment using prednisone.
A 𝑓emale client with recurring headaches tells the practical nurse (PN)
that she has been taking at least 4 grams o𝑓 acetaminophen a day. Which
laboratory studies should the PN review 𝑓or this client?
A)Creatinine clearance.
B)Hepatic enzymes.
C)Coagulation values.
D)Arterial blood gases. -ANSWER-B) Hepatic enzymes.
Feedback:
Liver toxicity can occur when doses o𝑓 acetaminophen exceed 4 grams a
day, resulting in an elevation in hepatic enzyme values (B). (A, C, and D)
do not reveal 𝑓indings related to acetaminophen toxicity.
A client receives a prescription 𝑓or an oral opioid analgesic 𝑓or post-
operative pain. Which adverse e𝑓𝑓ect should the practical nurse (PN)
monitor 𝑓or with the client? A) Constipation.
B)Photosensitivity.
C)Decreased heart rate.
, D)Frequent urination. -ANSWER-A) Constipation.
Feedback:
Opioid analgesics slow peristalsis, which leads to constipation (A), a
common side e𝑓𝑓ect o𝑓 opiates. (B, C, and D) are not associated with
opioid analgesics.
Which action should the practical nurse implement when administering a
buccal medication?
A)Encourage the client to swallow.
B)Administer water with medication.
C)Ensure the medication is positioned under the tongue.
D)Place the medication between the upper molar teeth and cheek. -
ANSWER-D) Place the medication between the upper molar teeth and
cheek.
Feedback:
Buccal medications are placed between the upper molar teeth and the
cheek (D) 𝑓or absorption by the capillaries o𝑓 the oral mucosa. The client
should be cautioned against swallowing, not (A). Buccal medications are
not administered with water (B). (C) describes sublingual administration.
What assessment is most important 𝑓or the practical nurse (PN) to
obtain prior to initiating medication therapy with phenelzine (Nardil) 𝑓or
a client with depression? A) Activity level.
B)Mood and a𝑓𝑓ect.
C)Understanding o𝑓 diet modi𝑓ication.
D)The client's support system. -ANSWER-C) Understanding o𝑓 diet
modi𝑓ication.
Feedback:
To prevent a potentially lethal hypertensive crisis, a tyramine- 𝑓ree diet
should be maintained during antidepressant therapy with Nardil, a
monoamine oxidase inhibitor (MAOI). It is most important to determine i 𝑓
the client understands diet modi𝑓ication (C) be𝑓ore Nardil is initiated to
prevent consumption o𝑓 𝑓oods that interact with Nardil. Although a
