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what is myasthenia gravis (MG)? autoimmune disorder attacks the acetylcholine
receptors at the postsynaptic muscle membrane.
Weakness starts at head - leads to respiratory
complications
Myasthenia Gravis is linked to what? Hyperplasia of thymus gland and Hyperthyroidism
Which diagnostics test is used for Tensilon Test : involves an injection of Tensilon
myasthenia gravis? (edrophonium), after which your muscle strength is
evaluated to determine whether your weakness is
caused by myasthenia gravis or not
Signs and symptoms of myasthenia Dyspnea, Dysarthia (slurred speech), Dysphagia
gravis? (difficulty swallowing), Ptosis (1 eye drooping),
Diplopia (double vision), Respiratory Compromise
(PRIORITY), facial weakness, Loss of bowel and
bladder control.
,Complications of MG Aspiration (priority due to airway), autoimmune
triggers (stress, sun, sickness/sepsis) can cause MG
crisis
Myasthenia Crisis: too little cholinesterase inhibitor
- svere generalized weakness, resp failure and HTN
Cholinergic Crisis: too much cholinergic meds
- increased weakness, (WET) hypersalivation,
sweating, increased bronchial secretions.
tx: Atropine
Treatment for Myasthenia Gravis Anticholinesterases (pyridostigmine) are used for
strength so give 30-60 min before
In severe cases, *PLASMAPHERESIS* or IVIG may
provide temporary relief (days to weeks)
Other: Corticosteroids, Surgical removal of Thymus
gland and Artificial tears
3 multiple choice options
what are Nursing Intervention for Oral hygiene, assess gag reflex, frequent rest
MG? periods
small frequent meals - soft diet, thick liquids
HOB elevated during and 30-60 min after pt eats
Daily Weights
bed side suction and mechanical vent
3 multiple choice options
, what is amyotrophic lateral sclerosis Progressive degeneration of motor neurons in the
(ALS)? brainstem and spinal cord leading to muscle
weakness/wasting and eventually leads to paralysis
of voluntary muscles (those affecting respiratory).
what are Signs & Symptoms of ALS? Fatigue, Muscle atrophy (including tongue), muscle
weakness, twitching of face, dysarthria (difficulty
speaking), Dysphagia, Stiff and clumsy gait, first
muscles affected are arms and legs (asymmetric),
no cognitive impairment.
3 multiple choice options
When does the acute phase of burn when wound healing or skin graft
resolve
what are Treatment / Management of NO CURE , management includes:
ALS? Riluzole (extends survival by a couple of months) -
liver toxic
Antispasmodics - valium ; dantrium
Pain control - NSAIDS; tramadol
Priority Nursing Intervention for PRIORITY: Advance Directives while they're still
ALS? able! (plan ahead)
Palliative care for symptom management at end of
life
3 multiple choice options