NURS 5334 PHARM FINAL EXAM REVIEW EXAM QUESTIONS
AND CORRECT VERIFIED ANSWERS ALL GRADED A+
DPP-4 inhibitors (gliptins) - CORRECT ANSWER ✔✔- Promote glycemic
control by enhancing the actions of the incretin hormones and stimulate
glucose dependent release of insulin; Suppress post-prandial release of
glucagon.
A1C reduction percentage - CORRECT ANSWER ✔✔- 0.5%.
Colesevelam in DM treatment - CORRECT ANSWER ✔✔- Bile acid
sequestrant used to lower cholesterol and helps lower blood glucose; Many
with diabetes also have high cholesterol so 2 birds-1 stone.
Paroxetine - CORRECT ANSWER ✔✔- An SSRI that may cause erectile
dysfunction.
Ethosuximide Monitoring - CORRECT ANSWER ✔✔- Patients should be
monitored for blood dyscrasias which are uncommon but possible.
Lamotrigine and OCPs Interaction - CORRECT ANSWER ✔✔- OCPs can
reduce lamotrigine levels, requiring an increase in the dose of lamotrigine.
Tricyclic Antidepressants Caution - CORRECT ANSWER ✔✔- Should be
prescribed cautiously in patients with CAD.
,Onset of Action Symptoms for SSRIs - CORRECT ANSWER ✔✔- Patients
may feel a bit of nausea, which resolves in about 1 week.
Pediatric Dosing Information - CORRECT ANSWER ✔✔- There is a lack of
evidence-based literature on the safe and effective use of medications in
children.
Neonates and Protein-Bound Drugs - CORRECT ANSWER ✔✔- Protein
binding is decreased in neonates, increasing the amount of free drug
available.
Adult Renal Function Age - CORRECT ANSWER ✔✔- Adult levels of renal
function are achieved at 12 months.
Beers List - CORRECT ANSWER ✔✔- A list that identifies drugs with a
high likelihood of causing adverse effects in the elderly.
Gastric Acidity in Pediatric Patients - CORRECT ANSWER ✔✔- Gastric
acidity does not reach adult values for 2 years.
Complications to Drug Therapy in the Elderly - CORRECT ANSWER ✔✔-
Include altered pharmacokinetics, multiple and severe illnesses, multiple-
drug therapy, and poor adherence.
Altered Absorption in the Elderly - CORRECT ANSWER ✔✔- May result in
a delay in drug response.
,Factors Altering Drug Distribution in the Elderly - CORRECT ANSWER
✔✔- Include increased body fat, decreased percentage of lean body mass,
decreased total body water, and reduced concentration of serum albumin.
Adverse Drug Reactions in the Elderly - CORRECT ANSWER ✔✔- The
most important cause of adverse drug reactions in the elderly is
polypharmacy.
Bupropion - CORRECT ANSWER ✔✔- An alternative medication that can
be added to help with erectile dysfunction caused by SSRIs.
Increased Seizure Activity with Ethosuximide - CORRECT ANSWER ✔✔-
Ethosuximide can induce seizures, so increased seizure activity should be
monitored.
Renal Dysfunction Monitoring - CORRECT ANSWER ✔✔- Patients on
ethosuximide should be monitored for renal dysfunction.
Weight Gain with OCPs - CORRECT ANSWER ✔✔- OCPs can cause
weight gain, which may be a concern for patients taking lamotrigine.
Hepatotoxicity with Ethosuximide - CORRECT ANSWER ✔✔-
Hepatotoxicity is a potential risk, but uncommon.
Contraceptive Failure with OCPs - CORRECT ANSWER ✔✔- OCPs may
lead to contraceptive failure when interacting with lamotrigine.
, Insomnia with SSRIs - CORRECT ANSWER ✔✔- Patients may experience
insomnia for a week after starting SSRIs.
FDA and Pediatric Dosing - CORRECT ANSWER ✔✔- The FDA does not
require pediatric dosing information for all medications.
Free Drug Availability in Neonates - CORRECT ANSWER ✔✔- Decreased
protein binding in neonates increases the amount of free drug available.
Proper index of renal function in the elderly - CORRECT ANSWER ✔✔-
Creatinine clearance or GFR.
Factors underlying increase in adverse reactions in geriatric population -
CORRECT ANSWER ✔✔- Polypharmacy, severe illness, multiple
pathologies, greater use of drugs that have a low therapeutic index,
inadequate supervision, poor patient adherence.
Maximum amount of Sumatriptan that can be taken in 1 day - CORRECT
ANSWER ✔✔- 200 mg.
Properties determining anesthetic penetration of axon membrane -
CORRECT ANSWER ✔✔- Molecular size, lipid solubility, degree of
ionization at tissue pH.
Medication that will not cause rebound headaches from overuse -
CORRECT ANSWER ✔✔- Propranolol.
AND CORRECT VERIFIED ANSWERS ALL GRADED A+
DPP-4 inhibitors (gliptins) - CORRECT ANSWER ✔✔- Promote glycemic
control by enhancing the actions of the incretin hormones and stimulate
glucose dependent release of insulin; Suppress post-prandial release of
glucagon.
A1C reduction percentage - CORRECT ANSWER ✔✔- 0.5%.
Colesevelam in DM treatment - CORRECT ANSWER ✔✔- Bile acid
sequestrant used to lower cholesterol and helps lower blood glucose; Many
with diabetes also have high cholesterol so 2 birds-1 stone.
Paroxetine - CORRECT ANSWER ✔✔- An SSRI that may cause erectile
dysfunction.
Ethosuximide Monitoring - CORRECT ANSWER ✔✔- Patients should be
monitored for blood dyscrasias which are uncommon but possible.
Lamotrigine and OCPs Interaction - CORRECT ANSWER ✔✔- OCPs can
reduce lamotrigine levels, requiring an increase in the dose of lamotrigine.
Tricyclic Antidepressants Caution - CORRECT ANSWER ✔✔- Should be
prescribed cautiously in patients with CAD.
,Onset of Action Symptoms for SSRIs - CORRECT ANSWER ✔✔- Patients
may feel a bit of nausea, which resolves in about 1 week.
Pediatric Dosing Information - CORRECT ANSWER ✔✔- There is a lack of
evidence-based literature on the safe and effective use of medications in
children.
Neonates and Protein-Bound Drugs - CORRECT ANSWER ✔✔- Protein
binding is decreased in neonates, increasing the amount of free drug
available.
Adult Renal Function Age - CORRECT ANSWER ✔✔- Adult levels of renal
function are achieved at 12 months.
Beers List - CORRECT ANSWER ✔✔- A list that identifies drugs with a
high likelihood of causing adverse effects in the elderly.
Gastric Acidity in Pediatric Patients - CORRECT ANSWER ✔✔- Gastric
acidity does not reach adult values for 2 years.
Complications to Drug Therapy in the Elderly - CORRECT ANSWER ✔✔-
Include altered pharmacokinetics, multiple and severe illnesses, multiple-
drug therapy, and poor adherence.
Altered Absorption in the Elderly - CORRECT ANSWER ✔✔- May result in
a delay in drug response.
,Factors Altering Drug Distribution in the Elderly - CORRECT ANSWER
✔✔- Include increased body fat, decreased percentage of lean body mass,
decreased total body water, and reduced concentration of serum albumin.
Adverse Drug Reactions in the Elderly - CORRECT ANSWER ✔✔- The
most important cause of adverse drug reactions in the elderly is
polypharmacy.
Bupropion - CORRECT ANSWER ✔✔- An alternative medication that can
be added to help with erectile dysfunction caused by SSRIs.
Increased Seizure Activity with Ethosuximide - CORRECT ANSWER ✔✔-
Ethosuximide can induce seizures, so increased seizure activity should be
monitored.
Renal Dysfunction Monitoring - CORRECT ANSWER ✔✔- Patients on
ethosuximide should be monitored for renal dysfunction.
Weight Gain with OCPs - CORRECT ANSWER ✔✔- OCPs can cause
weight gain, which may be a concern for patients taking lamotrigine.
Hepatotoxicity with Ethosuximide - CORRECT ANSWER ✔✔-
Hepatotoxicity is a potential risk, but uncommon.
Contraceptive Failure with OCPs - CORRECT ANSWER ✔✔- OCPs may
lead to contraceptive failure when interacting with lamotrigine.
, Insomnia with SSRIs - CORRECT ANSWER ✔✔- Patients may experience
insomnia for a week after starting SSRIs.
FDA and Pediatric Dosing - CORRECT ANSWER ✔✔- The FDA does not
require pediatric dosing information for all medications.
Free Drug Availability in Neonates - CORRECT ANSWER ✔✔- Decreased
protein binding in neonates increases the amount of free drug available.
Proper index of renal function in the elderly - CORRECT ANSWER ✔✔-
Creatinine clearance or GFR.
Factors underlying increase in adverse reactions in geriatric population -
CORRECT ANSWER ✔✔- Polypharmacy, severe illness, multiple
pathologies, greater use of drugs that have a low therapeutic index,
inadequate supervision, poor patient adherence.
Maximum amount of Sumatriptan that can be taken in 1 day - CORRECT
ANSWER ✔✔- 200 mg.
Properties determining anesthetic penetration of axon membrane -
CORRECT ANSWER ✔✔- Molecular size, lipid solubility, degree of
ionization at tissue pH.
Medication that will not cause rebound headaches from overuse -
CORRECT ANSWER ✔✔- Propranolol.
