APHON CERTIFICATION EVALUATION 2026
QUESTIONS WITH PRACTICE SOLUTION
GRADED A+
◉ What are the top 2 pediatric oncology diagnoses + the % Answer:
1. Leukemia - 29%
2. Brain / CNS - 26%
◉ What is the 5 yr survival rate for all peds onc diagnoses?
For ALL?
For AML? Answer: All Dx: > 80%
ALL: 90%
AML: 65%
◉ Natural cell death Answer: Apoptosis
◉ Cell death from an insult that leads to rupture of the cell
membrane and spilling of cell contents Answer: Necrosis
◉ Regulates normal cell growth and repair Answer: Proto-
oncogenes
, ◉ Blood cell production Answer: Hematopoiesis
◉ Period of time when the pt's WBCs are the lowest, from day 7-10
Answer: Nadir
◉ What time is when a pt is at the greatest risk for infection Answer:
During Nadir
◉ Goal of chemo Answer: Stop cell cycle/growth from occurring and
coming back
◉ Why are multiple chemo agents used? Answer: Resistance to a
single chemo agent can occur
◉ Chemo cells OUT of bone marrow and in the peripheral system
Answer: Blasts
◉ Chemotherapy affects 4 things Answer: 1. Malignant cells
2. Epidermal
3. Bone Marrow
4. Epithelial lining
QUESTIONS WITH PRACTICE SOLUTION
GRADED A+
◉ What are the top 2 pediatric oncology diagnoses + the % Answer:
1. Leukemia - 29%
2. Brain / CNS - 26%
◉ What is the 5 yr survival rate for all peds onc diagnoses?
For ALL?
For AML? Answer: All Dx: > 80%
ALL: 90%
AML: 65%
◉ Natural cell death Answer: Apoptosis
◉ Cell death from an insult that leads to rupture of the cell
membrane and spilling of cell contents Answer: Necrosis
◉ Regulates normal cell growth and repair Answer: Proto-
oncogenes
, ◉ Blood cell production Answer: Hematopoiesis
◉ Period of time when the pt's WBCs are the lowest, from day 7-10
Answer: Nadir
◉ What time is when a pt is at the greatest risk for infection Answer:
During Nadir
◉ Goal of chemo Answer: Stop cell cycle/growth from occurring and
coming back
◉ Why are multiple chemo agents used? Answer: Resistance to a
single chemo agent can occur
◉ Chemo cells OUT of bone marrow and in the peripheral system
Answer: Blasts
◉ Chemotherapy affects 4 things Answer: 1. Malignant cells
2. Epidermal
3. Bone Marrow
4. Epithelial lining
