ANSWERS 2026
Management of BMI >/= 25 - CORRECT ANSWER - -Diet, Exercise, Behavior
Management of BMI >/=30 - CORRECT ANSWER - -Diet, exercise, behavior + pharmacotherapy
Management of BMI >/= 27 + comorbidity - CORRECT ANSWER - -
Diet, exercise, behavior + pharmacotherapy
Management of BMI >/=35 + cormorbidity - CORRECT ANSWER - -Bariatric surgery
Management of BMI >/=40 - CORRECT ANSWER - -Bariatric surgery
Co-morbidities - CORRECT ANSWER - -T2DM
HTN
OSA and other respiratory disorders
NAFLD
OA
lipid abnormalities
gastrointestinal disorders
heart disease
Medication assessment - CORRECT ANSWER - -Every month x3 months, then every 3 months
Effective weight loss % - CORRECT ANSWER - ->/=5% in 3 months
Avoid these wt loss meds with HTN/HD - CORRECT ANSWER - -
Sympathomimetics (phentermine/diethylproprion)
,Avoid these wt loss medications with CVD - CORRECT ANSWER - -Sypathomimetics
T2DM treatment + medications to support weight loss - CORRECT ANSWER - -GLP-
1 analog (mitigates associated weight gain due to insulin) or SGLT-
2 inhibitors + metformin. If using insulin, recommend basal instead of combo
Drugs that induce weight gain - CORRECT ANSWER - -Tricyclic antidepressants
(Amitriptyline) oral contraceptives (Ortho Tri-Cyclen, Yaz)
antipsychotics (Risperidone)
anticonvulsants
glucocorticoids (cortisol)
sulfonyureas- ( Glimepiride, Glipizide)
glitazones (Actos)
B-blockers (Propranolol, Metoprolol, Atenolol)
Hormonal signals for appetite - CORRECT ANSWER - -CCK-
duodenum K cells- duodenum and jejunum: gatric inhibitory
polypeptide
PYY- ileum and colon
GLP-1 -ileum
Pancreas- Insulin
Adipose tissue: Leptin
Liver- glucagon
GLP-1 - CORRECT ANSWER - -
Secreted in response to glucose and promotes insulin release from pancreas and satiety
Ghrelin - CORRECT ANSWER - -produced in the stomach, orexigenic
, Leptin - CORRECT ANSWER - -proportional to fat mass, anorexigenic
Inhibits appetite
PYY - CORRECT ANSWER - -Ileum and colon, anorexigenic
CCK - CORRECT ANSWER - -duodenum, anorexigenic
Insulin - CORRECT ANSWER - -Pancreas, anorexigenic
Phentermine - CORRECT ANSWER - -noradrenergic, dopaminergic sympathomimetic amine
Start with 7.5-15mg/d, increase only with no results
Do not prescribe for someone with hx of psych dz or substance abuse
Lorcaserin (Belviq) - CORRECT ANSWER - -Seratonin agent, stimulates seratonin type 2 receptor
Brand name: Phentermine/Topiramate - CORRECT ANSWER - -Qysemia
Phentermine/Topiramate (Qysemia) - CORRECT ANSWER - -Phentermine- stimulant
Topiramate- neurostabilizer + antiseizure
Bupropion (Wellbutrin) - CORRECT ANSWER - -Dopamine + norepinepherine reuptake inhibitor
Stimulates POMC neurons