OCR SUMMER 2026
PREDICTED PAPER
A Level B (Advancing Biology)
H422/03 Practical skills in biology
Time allowed: 1 hour 30 minutes
You can use:
a scientific or graphical calculator
a ruler (cm/mm)
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use
the lined pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be
given for using acorrect method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 60.
• The marks for each question are shown in brackets [ ].
• Quality of extended response will be assessed in questions marked with an asterisk (*).
• This document has 20 pages.
ADVICE
• Read each question carefully before you start your answer.
Turn over
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, 1 Epidemiologists study the patterns, distribution, and causes of infectious diseases in
populations.
(a) Define the terms endemic and pandemic.
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
.............................................................................................................................................. [2]
(b) Figure 1.1 shows the number of TB cases and the rate per 100,000 population in the UK
between 2000 and 2012.
Fig 1.1
(i) Describe the changes in the incidence rate of TB between 2000 and 2012. Use data from
figure 1.1 in your answer.
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
.............................................................................................................................................. [2]
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, (ii) The incidence rate of TB was 11 per 100,000 in 2005 and 14 per 100,000 in 2012.
Calculate the percentage increase in the incidence rate between 2005 and 2012. Show
your working.
percentage increase...................................... [2]
(c) Scientists investigated the diversity of bacterial species causing TB infections in two
different regions of the UK. They sampled bacterial strains from infected patients in each
region. The table shows the results from Region A.
Use the formula: D = 1 − (Σ(n/N)²)
n = number of individuals of each species present in the sample
N = total number of all individuals of all species
Bacterial Strain n n/N (n/N)²
Strain 1 20 0.267 0.071
Strain 2 15 0.200 0.040
Strain 3 25 0.333 0.111
Strain 4 10 0.133 0.018
Strain 5 5
Σ=
for more: tyrionpapers.com
PREDICTED PAPER
A Level B (Advancing Biology)
H422/03 Practical skills in biology
Time allowed: 1 hour 30 minutes
You can use:
a scientific or graphical calculator
a ruler (cm/mm)
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use
the lined pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be
given for using acorrect method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 60.
• The marks for each question are shown in brackets [ ].
• Quality of extended response will be assessed in questions marked with an asterisk (*).
• This document has 20 pages.
ADVICE
• Read each question carefully before you start your answer.
Turn over
for more: tyrionpapers.com
, 1 Epidemiologists study the patterns, distribution, and causes of infectious diseases in
populations.
(a) Define the terms endemic and pandemic.
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
.............................................................................................................................................. [2]
(b) Figure 1.1 shows the number of TB cases and the rate per 100,000 population in the UK
between 2000 and 2012.
Fig 1.1
(i) Describe the changes in the incidence rate of TB between 2000 and 2012. Use data from
figure 1.1 in your answer.
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
.............................................................................................................................................. [2]
for more: tyrionpapers.com
, (ii) The incidence rate of TB was 11 per 100,000 in 2005 and 14 per 100,000 in 2012.
Calculate the percentage increase in the incidence rate between 2005 and 2012. Show
your working.
percentage increase...................................... [2]
(c) Scientists investigated the diversity of bacterial species causing TB infections in two
different regions of the UK. They sampled bacterial strains from infected patients in each
region. The table shows the results from Region A.
Use the formula: D = 1 − (Σ(n/N)²)
n = number of individuals of each species present in the sample
N = total number of all individuals of all species
Bacterial Strain n n/N (n/N)²
Strain 1 20 0.267 0.071
Strain 2 15 0.200 0.040
Strain 3 25 0.333 0.111
Strain 4 10 0.133 0.018
Strain 5 5
Σ=
for more: tyrionpapers.com
