OCR SUMMER 2026
PREDICTED PAPER
A Level Biology B (Advancing Biology)
H422/02 Scientific literacy in biology
Time allowed: 2 hours 15 minutes
You can use:
a scientific or graphical calculator
a ruler (cm/mm)
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use
the lined pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be
given for using acorrect method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 100.
• The marks for each question are shown in brackets [ ].
• Quality of extended response will be assessed in questions marked with an asterisk (*).
• This document has 28 pages.
ADVICE
• Read each question carefully before you start your answer.
Turn over
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, 2
1 The figure 1.1 shows the relationship between blood plasma, tissue fluid, and
lymph.
Fig 1.1
The table shows some components found in mammalian body fluids.
Component Blood Plasma Tissue Fluid Lymph
Large plasma proteins Present Absent
Red blood cells Present Absent
White blood cells Present Absent
Glucose High Low
Urea Present
for more: tyrionpapers.com
, 3
(a) Complete the table by writing Present, Absent, High, or Low in the spaces provided.
[3]
(b) Using figure 1.1 and your knowledge, describe and explain the process of
ultrafiltration at the arterial end of the capillaries.
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
.............................................................................................................................................. [3]
(c) A man has a total blood volume of 5.0 litres. Blood plasma makes up 55% of total
blood volume. One tenth of tissue fluid drains into the lymphatic system. The volume of
tissue fluid is three times the volume of blood plasma.
Calculate the volume of lymph produced. Show your working and give your answer to
one decimal place.
Volume of lymph....................... [3]
for more: tyrionpapers.com
PREDICTED PAPER
A Level Biology B (Advancing Biology)
H422/02 Scientific literacy in biology
Time allowed: 2 hours 15 minutes
You can use:
a scientific or graphical calculator
a ruler (cm/mm)
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use
the lined pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be
given for using acorrect method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 100.
• The marks for each question are shown in brackets [ ].
• Quality of extended response will be assessed in questions marked with an asterisk (*).
• This document has 28 pages.
ADVICE
• Read each question carefully before you start your answer.
Turn over
for more: tyrionpapers.com
, 2
1 The figure 1.1 shows the relationship between blood plasma, tissue fluid, and
lymph.
Fig 1.1
The table shows some components found in mammalian body fluids.
Component Blood Plasma Tissue Fluid Lymph
Large plasma proteins Present Absent
Red blood cells Present Absent
White blood cells Present Absent
Glucose High Low
Urea Present
for more: tyrionpapers.com
, 3
(a) Complete the table by writing Present, Absent, High, or Low in the spaces provided.
[3]
(b) Using figure 1.1 and your knowledge, describe and explain the process of
ultrafiltration at the arterial end of the capillaries.
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
.............................................................................................................................................. [3]
(c) A man has a total blood volume of 5.0 litres. Blood plasma makes up 55% of total
blood volume. One tenth of tissue fluid drains into the lymphatic system. The volume of
tissue fluid is three times the volume of blood plasma.
Calculate the volume of lymph produced. Show your working and give your answer to
one decimal place.
Volume of lymph....................... [3]
for more: tyrionpapers.com
