Psychopharmacology: Drugs, the Brain, and Behavior 3rd Edition by Meyer & Quenzer – Neuroscience & Pharmacology Textbook

TESTBANK
v

, Chapter1:PrinciplesofPharmacology v v v v




Multiple Choice v




1. refer(s) to specific molecular changes that occur when a drug binds to a v v v v v v v v v v v v




particular target site or receptor, while
v v aretheresultingwidespreadalterations v v v v v v v v




in function.
v v




a. Drugaction;therapeutic effects
v v v




b. Sideeffects; drugeffects
v v v




c. Therapeuticeffects; sideeffects v v v




d. Drugaction; drugeffects v v v




Answer:d v




TextbookReference:Pharmacology: TheScience ofDrugAction
v v v v v v v




2. Afterdrugadministration has occurred,theamount ofdruginthebloodthatis freeto bind at
v v v v v v v v v v v v v v v v v




specific target sites is referred to as
v v v v v v v




a. thetherapeuticdose.
v v




b. first-passeffects. v




c. bioavailability.
d. ED50.
Answer:c v




TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction
v v v v v v




3. Thespecificmolecularchangesthatoccurwhen a drugbindstoaparticulartarget site or
v v v v v v v v v v v v v v v




receptor are referred to as
v v v v v




a. drugeffects. v




b. drugaction. v




c. sideeffects.
v




d. placeboeffects. v




Answer:b v




TextbookReference:Pharmacology: TheScience ofDrugAction
v v v v v v v




4. Whichofthefollowing is not apossible explanation forplacebo effects?
v v v v v v v v v v v




a. Pavlovianconditioning v




b. Geneticvariation v




c. Drugcompetition v




d. Expectationofoutcome v v




Answer:c v




TextbookReference:Pharmacology: TheScience ofDrugAction
v v v v v v v




Page1of 247
v v v

,5. The administrationofoxytocin hasbeen proposed asa treatmentfor autism. v v v v v v v v v v




a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer:c v




TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction
v v v v v v




6. Whichfactor does not affect thepharmacokinetics ofadrug?
v v v v v v v v v




a. Route ofadministration v v




b. Lipid solubilityv




c. Depotbinding v




d. Drugaction v




Answer:d v




TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction
v v v v v v




7. First-passmetabolism occurswhen drugs aretaken v v v v v v




a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer:a v




TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction
v v v v v v




8. Theareapostrema is one area in the brain wherethe
v isnot complete.
v v v v v v v v v v v




a. cerebrospinalfluid v




b. blood–brainbarrier v




c. choroidplexus v




d. phospholipid membrane v




Answer:b v




TextbookReference:PharmacokineticFactorsDeterminingDrugAction
v v v v v v




9. First-passmetabolism occurs withorallyadministereddrugsbecause
v v v v v v v




a. theirabsorption is slowed byfood.
v v v v v




b. drugsabsorbedintothebloodstream from thestomachgototheliveronthewayto general
v v v v v v v v v v v v v v v v




circulation.
v




c. drugsmust first survivethe acidic environment of thestomach.
v v v v v v v v v




d. salivaryenzymes in the mouth begin theprocess of metabolism.
v v v v v v v v v




Answer:b v




TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction
v v v v v v




10. Toxicsubstances in theblood trigger avomitingresponse byactivatingthe
v v v v v v v v v v v




a. blood–brainbarrier. v




b. choroidplexus. v




c. areapostrema.
v




d. medianeminence. v




Page2of 247
v v v

, Answer:c v




TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction
v v v v v v




11. Drugsadministered _ havethe most rapid onset ofaction.
v v v v v v v v




a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer:d v




TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction
v v v v v v




12. Ionization of a drug depends on the of the solution and the v v v v v v v v v v ofthe
v




drug.
v




a. pH; pKa
v




b. pKa; pH v




c. concentration;lipid solubility v v




d. pH;concentration
v




Answer:a v




TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction
v v v v v v




13. Theabsorption of adrug depends on all of the following except
v v v v v v v v v v v




a. lipidsolubility. v




b. ionization.
c. bodytemperature. v




d. theconcentration ofthe drug.
v v v v




Answer:c v




TextbookReference:PharmacokineticFactorsDeterminingDrugAction
v v v v v v




14. Drugs that are should beavoided bywomen of childbearing age.
v v v v v v v v v




a. teratogenic
b. ableto crossthe placental barrier
v v v v v




c. psychoactive
d. highlylipid-soluble v




Answer:a v




TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction
v v v v v v




15. Agentsthat inducedevelopmental abnormalities in afetus areknown as
v v v v v v v v v v




a. psychoactivedrugs. v




b. illicitdrugs. v




c. teratogens.
d. placentaldrugs. v




Answer:c v




TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction
v v v v v v




16. Depot bindingis said tooccurwhen drugs v v v v v v v




a. bindtotheirtarget sites.
v v v v




Page3of 247
v v v