1
Sepsis
SIRS - Correct answer- >38 or <36
HR >90
RR >20 or pCO2 <32
WBC <4000 or >12000 (or >10% bands)
Sepsis = 2 criteria + source
Severe Sepsis - Correct answer- Sepsis + Hypotension or organ
dysfunction
AMS, renal insufficiency, abnormal coags, abnormal glucose,
lactate >2
Surviving Sepsis - Correct answer- At 3 hours:
-Lactate level
-blood cultures
-IVF 30 mL/kg
-Abx
1
, 2
Unknown Infection - Correct answer- Levaquin 750 mg +
Vancomycin 1 g + Gentamicin 7 mg/kg
-Imipenem is alternative
ENT/Dental Infection - Correct answer- PCN G 4 million units
+ Clindamycin 900 mg + Flagyl 1 g
Meningitis - Correct answer- Ceftriaxone 2 g + Vancomycin 1 g
+ Dex 10 mg
-1 month: Ampicillin 50-75 mg/kg + Cefotaxime 50-75 mg/kg
->1 month: Ceftriaxone 100 mg/kg + Ampicillin
-avoid Ceftriaxone in <30 days due to bilirubin
Pulmonary Infection - Correct answer- Levaquin 750 mg +
Vanc +/- Gentamicin
-Alternate is Ceftriaxone 1-2 g + Azithromycin 500 mg
GI/UG Infection - Correct answer- Zosyn 3.375 g or Unasyn 3 g
+/- Gent
Skin Infection - Correct answer- Zosyn 3.375 g + Vanc 1 g +
Gent 7 mg/kg
2
Sepsis
SIRS - Correct answer- >38 or <36
HR >90
RR >20 or pCO2 <32
WBC <4000 or >12000 (or >10% bands)
Sepsis = 2 criteria + source
Severe Sepsis - Correct answer- Sepsis + Hypotension or organ
dysfunction
AMS, renal insufficiency, abnormal coags, abnormal glucose,
lactate >2
Surviving Sepsis - Correct answer- At 3 hours:
-Lactate level
-blood cultures
-IVF 30 mL/kg
-Abx
1
, 2
Unknown Infection - Correct answer- Levaquin 750 mg +
Vancomycin 1 g + Gentamicin 7 mg/kg
-Imipenem is alternative
ENT/Dental Infection - Correct answer- PCN G 4 million units
+ Clindamycin 900 mg + Flagyl 1 g
Meningitis - Correct answer- Ceftriaxone 2 g + Vancomycin 1 g
+ Dex 10 mg
-1 month: Ampicillin 50-75 mg/kg + Cefotaxime 50-75 mg/kg
->1 month: Ceftriaxone 100 mg/kg + Ampicillin
-avoid Ceftriaxone in <30 days due to bilirubin
Pulmonary Infection - Correct answer- Levaquin 750 mg +
Vanc +/- Gentamicin
-Alternate is Ceftriaxone 1-2 g + Azithromycin 500 mg
GI/UG Infection - Correct answer- Zosyn 3.375 g or Unasyn 3 g
+/- Gent
Skin Infection - Correct answer- Zosyn 3.375 g + Vanc 1 g +
Gent 7 mg/kg
2
