McCance & Huether’s Pathophysiology:
The Biologic Basis for Disease in Adults
and Children 9th Edition by Julia Rogers
TEST BANK
VERIFIED CHAPTERS 1-49|
VERIFIED QUESTIONS & ANSWERS
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Page 1 of 659
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, Chapter 01: Cellular Biology
MULTIPLE CHOICE
1. Which statement best describes the cellular function of metabolic absorption?
a. Cells can produce proteins.
b. Cells can secrete digestive enzymes.
c. Cells can take in and use nutrients.
d. Cells can synthesize fats.
ACCURATE ANSWER> C
In metabolic absorption, all cells take in and use nutrients and other substances from their
surroundings. The remaining options are not inclusive in their descriptions of cellular metabolic
absorption.
DIF: Cognitive Level: Remembering
2. Where is most of a cell’s genetic information, including RNA and DNA, contained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome
ACCURATE ANSWER> C
The nucleus contains the nucleolus, a small dense structure composed largely of RNA, most of the
cellular DNA, and the DNA-binding proteins, such as the histones, which regulate its activity. The
mitochondria are responsible for cellular respiration and energy production. Ribosomes’ chief
function is to provide sites for cellular protein synthesis. Lysosomes function as the intracellular
digestive system.
DIF: Cognitive Level: Remembering
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,3. Which component of the cell produces hydrogen peroxide (H2O2) by using oxygen to remove
hydrogen atoms from specific substrates in an oxidative reaction?
a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome
ACCURATE ANSWER> B
Peroxisomes are so named because they usually contain enzymes that use oxygen to remove
hydrogen atoms from specific substrates in an oxidative reaction that produces H2O2, which is a
powerful oxidant and potentially destructive if it accumulates or escapes from peroxisomes.
Ribosomes are RNA-protein complexes (nucleoproteins) that are synthesized in the nucleolus and
secreted into the cytoplasm through pores in the nuclear envelope called nuclear pore complexes.
Lysosomes are saclike structures that originate from the Golgi complex and contain more than 40
digestive enzymes called hydrolases, which catalyze bonds in proteins, lipids, nucleic acids, and
carbohydrates. An endosome is a vesical that has been pinched off from the cellular membrane.
DIF: Cognitive Level: Remembering
4. Which cell component is capable of cellular autodigestion when it is released during cell injury?
a. Ribosome
b. Golgi complex
c. Smooth endoplasmic reticulum
d. Lysosomes
ACCURATE ANSWER> D
The lysosomal membrane acts as a protective shield between the powerful digestive enzymes within
the lysosome and the cytoplasm, preventing their leakage into the cytoplasmic matrix. Disruption of
the membrane by various treatments or cellular injury leads to a release of the lysosomal enzymes,
which can then react with their specific substrates, causing cellular self- digestion. The chief function
of a ribosome is to provide sites for cellular protein synthesis. The Golgi complex is a network of
flattened, smooth vesicles and membranes often located near the cell nucleus. The smooth
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endoplasmic reticulum is involved in steroid hormone production and removing toxic substances
from the cell.
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DIF: Cognitive Level: Remembering
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, 5. Which cAMP-mediated response is related to antidiuretic hormone?
a. Increased heart rate and force of contraction
b. Secretion of cortisol
c. Increased retention of water
d. Breakdown of fat
ACCURATE ANSWER> C
Antidiuretic hormone leads to increased retention of water in the body. Epinephrine causes increases
in heart rate and force of contraction. Increased cortisol secretion is due to ACTH. Breakdown of fat
is due to glucagon.
DIF: Cognitive Level: Remembering
6. During which phase of the cell cycle is DNA synthesized?
a. G1
b. S
c. G2
d. M
ACCURATE ANSWER> B
The four designated phases of the cell cycle are: (1) the G1 phase (G = gap), which is the period
between the M phase (M = mitosis) and the start of DNA synthesis; (2) the S phase (S= synthesis),
during which DNA is synthesized in the cell nucleus; (3) the G2 phase, during which RNA and
protein synthesis occurs, the period between the completion of DNA synthesis and the next phase
(M); and (4) the M phase, which includes nuclear and cytoplasmic division.
DIF: Cognitive Level: Remembering
7. What organic compound facilitates transportation across cell membranes by acting as receptors,
transport channels for electrolytes, and enzymes to drive active pumps?
a. Lipids
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b. Proteases
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The Biologic Basis for Disease in Adults
and Children 9th Edition by Julia Rogers
TEST BANK
VERIFIED CHAPTERS 1-49|
VERIFIED QUESTIONS & ANSWERS
St
ud
yS
Page 1 of 659
H
, Chapter 01: Cellular Biology
MULTIPLE CHOICE
1. Which statement best describes the cellular function of metabolic absorption?
a. Cells can produce proteins.
b. Cells can secrete digestive enzymes.
c. Cells can take in and use nutrients.
d. Cells can synthesize fats.
ACCURATE ANSWER> C
In metabolic absorption, all cells take in and use nutrients and other substances from their
surroundings. The remaining options are not inclusive in their descriptions of cellular metabolic
absorption.
DIF: Cognitive Level: Remembering
2. Where is most of a cell’s genetic information, including RNA and DNA, contained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome
ACCURATE ANSWER> C
The nucleus contains the nucleolus, a small dense structure composed largely of RNA, most of the
cellular DNA, and the DNA-binding proteins, such as the histones, which regulate its activity. The
mitochondria are responsible for cellular respiration and energy production. Ribosomes’ chief
function is to provide sites for cellular protein synthesis. Lysosomes function as the intracellular
digestive system.
DIF: Cognitive Level: Remembering
St
ud
yS
Page 2 of 659
H
,3. Which component of the cell produces hydrogen peroxide (H2O2) by using oxygen to remove
hydrogen atoms from specific substrates in an oxidative reaction?
a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome
ACCURATE ANSWER> B
Peroxisomes are so named because they usually contain enzymes that use oxygen to remove
hydrogen atoms from specific substrates in an oxidative reaction that produces H2O2, which is a
powerful oxidant and potentially destructive if it accumulates or escapes from peroxisomes.
Ribosomes are RNA-protein complexes (nucleoproteins) that are synthesized in the nucleolus and
secreted into the cytoplasm through pores in the nuclear envelope called nuclear pore complexes.
Lysosomes are saclike structures that originate from the Golgi complex and contain more than 40
digestive enzymes called hydrolases, which catalyze bonds in proteins, lipids, nucleic acids, and
carbohydrates. An endosome is a vesical that has been pinched off from the cellular membrane.
DIF: Cognitive Level: Remembering
4. Which cell component is capable of cellular autodigestion when it is released during cell injury?
a. Ribosome
b. Golgi complex
c. Smooth endoplasmic reticulum
d. Lysosomes
ACCURATE ANSWER> D
The lysosomal membrane acts as a protective shield between the powerful digestive enzymes within
the lysosome and the cytoplasm, preventing their leakage into the cytoplasmic matrix. Disruption of
the membrane by various treatments or cellular injury leads to a release of the lysosomal enzymes,
which can then react with their specific substrates, causing cellular self- digestion. The chief function
of a ribosome is to provide sites for cellular protein synthesis. The Golgi complex is a network of
flattened, smooth vesicles and membranes often located near the cell nucleus. The smooth
St
endoplasmic reticulum is involved in steroid hormone production and removing toxic substances
from the cell.
ud
DIF: Cognitive Level: Remembering
yS
Page 3 of 659
H
, 5. Which cAMP-mediated response is related to antidiuretic hormone?
a. Increased heart rate and force of contraction
b. Secretion of cortisol
c. Increased retention of water
d. Breakdown of fat
ACCURATE ANSWER> C
Antidiuretic hormone leads to increased retention of water in the body. Epinephrine causes increases
in heart rate and force of contraction. Increased cortisol secretion is due to ACTH. Breakdown of fat
is due to glucagon.
DIF: Cognitive Level: Remembering
6. During which phase of the cell cycle is DNA synthesized?
a. G1
b. S
c. G2
d. M
ACCURATE ANSWER> B
The four designated phases of the cell cycle are: (1) the G1 phase (G = gap), which is the period
between the M phase (M = mitosis) and the start of DNA synthesis; (2) the S phase (S= synthesis),
during which DNA is synthesized in the cell nucleus; (3) the G2 phase, during which RNA and
protein synthesis occurs, the period between the completion of DNA synthesis and the next phase
(M); and (4) the M phase, which includes nuclear and cytoplasmic division.
DIF: Cognitive Level: Remembering
7. What organic compound facilitates transportation across cell membranes by acting as receptors,
transport channels for electrolytes, and enzymes to drive active pumps?
a. Lipids
St
b. Proteases
ud
yS
Page 4 of 659
H
