PALS PEDIATRIC ADVANCED LIFE SUPPORT
EXAMPREP STUDY GUIDE 2026 FULL
QUESTIONS AND CORRECT ANSWERS
▶ MOA of Naloxone (Narcan)? Answer:competitive opioid receptor
antagonist
▶ MOA of naltrexone? Answer:competitive opioid receptor antagonist
▶ MOA of Methadone (Dolophine)? Answer:long acting FULL opioid
receptor agonist (at mu receptor)
▶ MOA of Suboxone (buprenorphine and naloxone)? Answer:partial opioid
agonist + competitive opioid antagonist
▶ Medication used in opioid overdose? Answer:naloxone
▶ Medication used in patients with chronic pain and opioid use disorder?
Answer:Suboxone (buprenorphine and naloxone)
▶ Which medications for opioid use disorder can precipitate withdrawal?
Answer:naloxone, naltrexone, Suboxone (buprenorphine)
▶ Which medication used to treat opioid use disorder has a "ceiling
effect"?? Answer:Buprenorphine... increasing the dose does not result in
increasing effects
▶ Which medication is available sublingual film/tab and buccal film for
opioid patients? Answer:Suboxone
▶ Which medication is available as sublingual tab, implant, and subQ
injection for opioid patients? Answer:Buprenorphine
▶ Which medication is available as a oral tablet and a monthly IM injection
for opioid patients?? Answer:Naltrexone
, ▶ Which medication is treatment of choice for highly motivated opioid use
disorder patients?? Answer:Naltrexone
▶ Inappropriate use of opioids may indicate? Answer:the patient's pain is
not well managed
▶ S/S of opioid intoxication? Answer:miosis (pinpoint pupils), hypotension,
bradycardia, low RR, unconsciousness
▶ S/S of opioif withdrawal? Answer:anxiety, lacrimation, muscle aches,
abdominal cramps, diarrhea, seizures
▶ When detoxing a patient from opioids, which medication is more effective
at suppressing and controlling withdrawal symptoms as the taper nears
completion- methadone or buprenorphine?? Answer:Buprenorphine
▶ Drugs used in opioid withdrawal? Answer:Suboxone, Clonidine, bentyl
▶ S/S Cocaine Intoxication? Answer:Auditory hallucinations, agitation,
violent behavior, muscle twitching, HTN, bradycardia
▶ S/S cocaine overdose? Answer:can cause acute heart failure, stroke,
seizures
▶ S/S of cocaine withdrawal? Answer:extreme fatigue, anhedonia (loss of
pleasure), depression, fatigue, brain fog, intense cravings,
▶ Medications used to treat cocaine induced chest pain and MI?
Answer:nitroglycerin, aspirin
▶ Medication to avoid in cocaine induced chest pain and MI?
Answer:metoprolol (betablockers are contraindicated in this population
because it further lowers coronary blood flow thereby increasing ischemia)
▶ Medication to treat cocain use disorder? Answer:Antabuse
▶ MOA of antabuse in cocaine use disorder? Answer:increases synaptic
dopamine in the brain reward circuit and act as an agonist treatment
EXAMPREP STUDY GUIDE 2026 FULL
QUESTIONS AND CORRECT ANSWERS
▶ MOA of Naloxone (Narcan)? Answer:competitive opioid receptor
antagonist
▶ MOA of naltrexone? Answer:competitive opioid receptor antagonist
▶ MOA of Methadone (Dolophine)? Answer:long acting FULL opioid
receptor agonist (at mu receptor)
▶ MOA of Suboxone (buprenorphine and naloxone)? Answer:partial opioid
agonist + competitive opioid antagonist
▶ Medication used in opioid overdose? Answer:naloxone
▶ Medication used in patients with chronic pain and opioid use disorder?
Answer:Suboxone (buprenorphine and naloxone)
▶ Which medications for opioid use disorder can precipitate withdrawal?
Answer:naloxone, naltrexone, Suboxone (buprenorphine)
▶ Which medication used to treat opioid use disorder has a "ceiling
effect"?? Answer:Buprenorphine... increasing the dose does not result in
increasing effects
▶ Which medication is available sublingual film/tab and buccal film for
opioid patients? Answer:Suboxone
▶ Which medication is available as sublingual tab, implant, and subQ
injection for opioid patients? Answer:Buprenorphine
▶ Which medication is available as a oral tablet and a monthly IM injection
for opioid patients?? Answer:Naltrexone
, ▶ Which medication is treatment of choice for highly motivated opioid use
disorder patients?? Answer:Naltrexone
▶ Inappropriate use of opioids may indicate? Answer:the patient's pain is
not well managed
▶ S/S of opioid intoxication? Answer:miosis (pinpoint pupils), hypotension,
bradycardia, low RR, unconsciousness
▶ S/S of opioif withdrawal? Answer:anxiety, lacrimation, muscle aches,
abdominal cramps, diarrhea, seizures
▶ When detoxing a patient from opioids, which medication is more effective
at suppressing and controlling withdrawal symptoms as the taper nears
completion- methadone or buprenorphine?? Answer:Buprenorphine
▶ Drugs used in opioid withdrawal? Answer:Suboxone, Clonidine, bentyl
▶ S/S Cocaine Intoxication? Answer:Auditory hallucinations, agitation,
violent behavior, muscle twitching, HTN, bradycardia
▶ S/S cocaine overdose? Answer:can cause acute heart failure, stroke,
seizures
▶ S/S of cocaine withdrawal? Answer:extreme fatigue, anhedonia (loss of
pleasure), depression, fatigue, brain fog, intense cravings,
▶ Medications used to treat cocaine induced chest pain and MI?
Answer:nitroglycerin, aspirin
▶ Medication to avoid in cocaine induced chest pain and MI?
Answer:metoprolol (betablockers are contraindicated in this population
because it further lowers coronary blood flow thereby increasing ischemia)
▶ Medication to treat cocain use disorder? Answer:Antabuse
▶ MOA of antabuse in cocaine use disorder? Answer:increases synaptic
dopamine in the brain reward circuit and act as an agonist treatment
