Microbiology Exam 6|Pathogenicity, Virulence, Adhesins, Capsules, Cell
Wall Components, Coagulase, Hyaluronidase, Collagenase, IgA Protease,
Antigenic Variation, Siderophores, Exotoxins, Endotoxins, AB Toxins,
Membrane-Disrupting Toxins, Superantigens, Cytotoxins, Neurotoxins,
Enterotoxins, Toxoids, Antitoxins, ID50, LD50, Portals of Entry, Portals of
Exit, Opportunistic Pathogens, Host Receptors, Selective Toxicity, Synthetic
Drugs, Antibiotics, Narrow-Spectrum Drugs, Broad-Spectrum Drugs, Drug
Resistance Exam Questions Verified and Provided with Complete A+ Graded
Rationales Latest Updated 2026
What is pathogenicity?
The ability to cause disease
What is virulence?
The extent (strength)of pathogenicity
What are the four steps that must occur for a microbe to cause disease?
1. Gain Access
2. Adhere to host tissues
3. Penetrate host defenses
4. Damage host tissue
Portals of entry:
Mucous membranes
Skin
Parenteral route (Deposited directly into tissues when barriers are penetrated)
,Skin is most resistant to infection when it is ___________________.
unbroken.
Parenteral Routes
Punctures
Injections
Bites
Cuts
Splitting of dry skin
Oral
Typhoid Fever (Salmonella typhi)
Inhaled
Mycobacterium tuberculosis
Parenteral
Clostridium tetani
Non-specific
Yersinia pestis
, What is ID50?
Infectious dose for 50% of the test population. The portal of entry can change the ID50.
What is LD50?
Lethal dose (of a toxin) for 50% of the test population
What do adhesins/ligands bind to on a host cell?
Receptors
What substances contain adhesins/ligands?
Glycocalyx
Fimbriae
M proteins
If you don't have the receptor that the microorganism can attach to will you be able to get the disease?
No
Host receptors are usually composed of what?
Sugars (usually mannose)
Streptococcus mutans attaches by:
Glycolax
Wall Components, Coagulase, Hyaluronidase, Collagenase, IgA Protease,
Antigenic Variation, Siderophores, Exotoxins, Endotoxins, AB Toxins,
Membrane-Disrupting Toxins, Superantigens, Cytotoxins, Neurotoxins,
Enterotoxins, Toxoids, Antitoxins, ID50, LD50, Portals of Entry, Portals of
Exit, Opportunistic Pathogens, Host Receptors, Selective Toxicity, Synthetic
Drugs, Antibiotics, Narrow-Spectrum Drugs, Broad-Spectrum Drugs, Drug
Resistance Exam Questions Verified and Provided with Complete A+ Graded
Rationales Latest Updated 2026
What is pathogenicity?
The ability to cause disease
What is virulence?
The extent (strength)of pathogenicity
What are the four steps that must occur for a microbe to cause disease?
1. Gain Access
2. Adhere to host tissues
3. Penetrate host defenses
4. Damage host tissue
Portals of entry:
Mucous membranes
Skin
Parenteral route (Deposited directly into tissues when barriers are penetrated)
,Skin is most resistant to infection when it is ___________________.
unbroken.
Parenteral Routes
Punctures
Injections
Bites
Cuts
Splitting of dry skin
Oral
Typhoid Fever (Salmonella typhi)
Inhaled
Mycobacterium tuberculosis
Parenteral
Clostridium tetani
Non-specific
Yersinia pestis
, What is ID50?
Infectious dose for 50% of the test population. The portal of entry can change the ID50.
What is LD50?
Lethal dose (of a toxin) for 50% of the test population
What do adhesins/ligands bind to on a host cell?
Receptors
What substances contain adhesins/ligands?
Glycocalyx
Fimbriae
M proteins
If you don't have the receptor that the microorganism can attach to will you be able to get the disease?
No
Host receptors are usually composed of what?
Sugars (usually mannose)
Streptococcus mutans attaches by:
Glycolax
