sedative-hypnotics
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Benzos
Barbituates
Misc Agents
51. Contraindications to the use of DRAs include what?
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, a. History of serious allergic response
b. Possible ingestion of a substance that will interact with the antipsychotic
to induce
i. CNS depression
1. Alcohol
2. Opioids
3. Barbiturates
4. Benzodiazepines
ii. Anticholinergic delirium
1. Scopolamine
2. Possibly phencyclidine [PCP]
c. Presence of a severe cardiac abnormality
d. A high risk for seizures
e. Presence of narrow-angle glaucoma or prostatic hypertrophy if a drug
with high anticholinergic activity is to be used
f. Presence or a history of tardive dyskinesia.
seratonin syndrome
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concurrent with MAOI, Triptan, Tramadol, Linezolid, lithium, St. Johns Wort
may start 2-72 hours after- can be LETHAL
confusion, fever, agitation, anxiety, hallucination, hyperflexia, diaphoresis,
tremors, hypertension
benzos -- Long acting are better
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anxiolytics and anticonvulsant drugs
,Clomipramine
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TCA
antidepressant
non SRI 1st line for OCD
-What is meant by a drug causing an Antagonist type of action at a receptor site?
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ANTAGONIST = Stops or significantly reduces signal. Binds to receptor,
blocking-action of an agonist
Competitive antagonists
Non-competitive antagonists - Antagonize agonists by other means than
direct competition
GABA is the
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predominant inhibitory neurotransmitter in the CNS.
Misc. (Sedative Hypnotics)
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, Buspirone
Chloral Hydrate
Eszopiclone
Ramelteon
Zaleplon
Zolpidem
ACh (Acetylcholine), Drugs that increase or mimic:
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Nicotine
muscarine
Chantix
nerve gases (VX, Sarin)
Alzheimer's drugs (Aricept, Exelon)
physostigmine
Tensilon
pilocarpine
Bupropion (Wellbutrin)
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NDRI
antidepressant
Tolerance
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Give this one a try later!
Benzos
Barbituates
Misc Agents
51. Contraindications to the use of DRAs include what?
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, a. History of serious allergic response
b. Possible ingestion of a substance that will interact with the antipsychotic
to induce
i. CNS depression
1. Alcohol
2. Opioids
3. Barbiturates
4. Benzodiazepines
ii. Anticholinergic delirium
1. Scopolamine
2. Possibly phencyclidine [PCP]
c. Presence of a severe cardiac abnormality
d. A high risk for seizures
e. Presence of narrow-angle glaucoma or prostatic hypertrophy if a drug
with high anticholinergic activity is to be used
f. Presence or a history of tardive dyskinesia.
seratonin syndrome
Give this one a try later!
concurrent with MAOI, Triptan, Tramadol, Linezolid, lithium, St. Johns Wort
may start 2-72 hours after- can be LETHAL
confusion, fever, agitation, anxiety, hallucination, hyperflexia, diaphoresis,
tremors, hypertension
benzos -- Long acting are better
Give this one a try later!
anxiolytics and anticonvulsant drugs
,Clomipramine
Give this one a try later!
TCA
antidepressant
non SRI 1st line for OCD
-What is meant by a drug causing an Antagonist type of action at a receptor site?
Give this one a try later!
ANTAGONIST = Stops or significantly reduces signal. Binds to receptor,
blocking-action of an agonist
Competitive antagonists
Non-competitive antagonists - Antagonize agonists by other means than
direct competition
GABA is the
Give this one a try later!
predominant inhibitory neurotransmitter in the CNS.
Misc. (Sedative Hypnotics)
Give this one a try later!
, Buspirone
Chloral Hydrate
Eszopiclone
Ramelteon
Zaleplon
Zolpidem
ACh (Acetylcholine), Drugs that increase or mimic:
Give this one a try later!
Nicotine
muscarine
Chantix
nerve gases (VX, Sarin)
Alzheimer's drugs (Aricept, Exelon)
physostigmine
Tensilon
pilocarpine
Bupropion (Wellbutrin)
Give this one a try later!
NDRI
antidepressant
Tolerance
Give this one a try later!
