WGU 785 Final Exam Latest 2021 Q&A

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Final Exam
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Latest2021
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Q&A
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,WGU 785 Final Exam Latest 2021 With v v v v v v




Complete Solution v




Hemophilia Pedigree - Father has hemophilia, mother does not. What is the outcome for
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their kids?
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Correct answer- His daughters would be carriers. This is x-link recessive.
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Autosomal:
Dominant:
Correct answer- Autosomal: males and females equally affected.
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Dominant: non-carrier parents
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polymerase chain reaction (PCR) v v v


Correct answer- The process of copying DNA in the lab. Uses Template DNA,
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Nucleotides (dNTPS), DNA Polymerase, and DNA primers.
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3 Steps of PCR
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Correct answer- 1. Denaturation: DNA is heated to 95C to separate it.
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2. Annealing: reaction is cooled to 50C; primers stick to the DNA you want to copy and
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add DNA polymerase.
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3. Elongation: reaction heated to 70C and DNA polymerase, adding nucleotides building
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a new DNA strand.
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Base Excision Repair (BER)
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Correct answer- How you repair a mutation. BER is used to repair damage to a base
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vcaused by harmful molecules. You remove the base that is damaged and replace it.
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*BER removes a single nucleotide*
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DNA glycolsylase - sees damaged DNA and removes it.
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DNA polymerase-puts the right one back in while DNA ligase seals it.
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Mismatch repair (MMR) occurs during:v v v v


Correct answer- replication. DNA polymerase proofreads but sometimes a mismatch
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pair gets through. MMR removes a large section of the nucleotides from the new DNA
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and DNA polymerase tries again. (Ex: C-T instead of C-A)
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Mismatch Repair corrects what kind of DNA damage?
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Correct answer- When a base is mismatched due to errors in replication. Such as G-T
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instead of G-C. DNA polymerase comes by and fixes it.
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What happens when DNA polymerase binds to DNA to make RNA?
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, Correct answer- TRANSCRIPTION! DNA polymerase takes the individual nucleotides
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and matches them to the parental sequences to ensure a correct pair. It must bind with
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RNA primer to work.
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What is needed for DNA replication?
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Correct answer- DNA polymerase
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Nonsense Mutation v




Correct answer- Change in 1 nucleotide produces a STOP codon Stop= nonsense
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because it is no more.
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Silent Mutation v


Correct answer- Change in 1 nucleotide but codes for the same amino acid. Silent= the
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change doesn't change the name of the protein
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Missense Mutation v


Correct answer- Change in 1 nucleotide leads to a code for a different amino acid.
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Missense = mistake was made.
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What happends during RNA splicing?
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Correct answer- During RNA splicing introns are cut out, the remaining exons are joined
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together.
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5'ATG AGT CTC TCT 3' v v v v


Find the DNA template strand.
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Correct answer- 3'TAC TCA GAG AGA 5'
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The DNA template strand is complimentary. So start with the opposite number, then go
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L-R with the complimentary letter.
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5'ATG AGT CTC TCT 3' v v v v


What is the corresonding mRNA sequence?
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Correct answer- 5'AUG AGU CUC UCU 3'
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This sequence is the same as the coding strand except T changes to U because it is
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RNA. RNA doesn't have T.
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How would a mutation from CTC to ATC affect the protein sequence? (CTC/ATC -
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coding strand, AUC - mRNA strand)
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Correct answer- This will make a missense mutation because it changes the name of
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the protein. (look at the chart provided.) missense = mistake
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DNA replication process
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Correct answer- DNA ->Transcription -> RNA -> Translation -> Polypeptide
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Describe how you would find what ionized Alanine looks like.
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