Gene cs -correct answers_________ is the study of inheritance!
Inheritance of transmissible characteris cs or 'traits': such as blood group an gens found on red
blood cells
GENES -correct answersSpecific regions of the chromosome (________) encode the informa on
for specific traits.
46 -correct answersHumans have ___ chromosomes, which are present in 23 pairs-one member
of each pair is inherited from each parent
Traits -correct answers_____ are the observed or outward expression of genes.
protein -correct answersEach gene codes for the produc on of a specific ________ by coding for
a sequence of amino acids or polypep des.
RBC An gens -correct answersStructures embedded or protruding from the RBC membrane.
An gens found in body fluids such as saliva, plasma, semen etc.. -correct answersWhat are
Soluble blood group substances (an gens)?
Specific protein. -correct answersEach gene codes for the produc on of a
,allele. Alleles in the ABO blood group system are A, B, and O -correct answersAlternate form of
a gene at a specific locus is an ________.
detectable gene -correct answersA silent allele is a gene that produces no _______ ______
product. In the ABO system the O allele is a silent allele, or amorph, because it produces no
detectable gene product.
Co-Dominant Inheritance -correct answersWhen mul ple alleles are inherited and both gene
products are expressed, such as A and B which are expressed as type AB
Homozygous Inheritance -correct answersIt is the inheritance of iden cal alleles at a given locus
or loca on on both chromosomes. In an example from the ABO system it is inheri ng an A gene
from mom and an A gene from dad.
Heterozygous Inheritance -correct answersIt is the inheritance of different alleles at a given
locus on both chromosomes. In an example from the ABO system it is inheri ng an A gene from
mom and an O gene from dad
Genotype -correct answersIt is the gene c cons tu on of an individual
Phenotype -correct answersIt is the outward expression of inherited characteris cs
Dosage -correct answersIn some blood group systems, persons homozygous for an allele have
MORE an gen on their red cells than persons heterozygous for an allele.
Varia on in an gen expression due to the number of alleles present is called __________
Rh, Duffy, MNSs, and KIDD -correct answersBlood groups that demonstrate dosage include
,Gene Frequencies -correct answersFrequency of a gene in a certain popula on
phenotype frequencies -correct answersGene Frequencies can only be extrapolated from
popula on studies using ___________ _________
Centers for Medicare and Medicaid Services -correct answersRegulatory Agencies
(CMS)
Food and Drug Administra on -correct answersRegulatory Agencies
(FDA)
American Associa on of Blood Banks -correct answersAccredi ng Agencies
(AABB)
Joint Commission -correct answersAccredi ng Agencies
(JC)
College of American Pathologists -correct answersAccredi ng Agencies
(CAP)
Drug -correct answersFDA defines blood as a "_____" thus it regulates it under those standards.
Quality Assurance -correct answersThe overall process of quality improvement and
maintenance in the en re blood bank.
Quality Control -correct answersRou ne tes ng of Blood Bank Reagents to insure potency,
calibra on of serofuges, taking temps on fridges and freezers, tes ng blood components, etc.
, Current Good Manufacturing Prac ces (cGMP) -correct answersFollowing guidelines found in
Standard Opera ng Procedures (SOP).
CLIA '88 -correct answers________ states that clinical laboratories must have a Quality
Assurance Plan in place.
Immune Response -correct answersPhysiological mechanism to fight disease or clear foreign
substances
Primary immune response -correct answersFirst exposure of a foreign agent able to elicit an
immune response.
Secondary immune response -correct answersSubsequent exposure of the same foreign agent
An gen -correct answersAn ________ is a substance capable of elici ng an immune response
when introduced into an immuncompetent individual to whom it is foreign.
An genicity -correct answers___________ is the ability of an an gen to induce an immune
response and combine with specific an bodies
Epitopes -correct answersAn ________ is the part of the an gen that the an body finds foreign
and a aches to. It is the structural site where the an body combines with the an gen
Size, shape, loca on, and the number of determinants or epitopes -correct answersAn genicity
of an An gen is affected by its:
foreign -correct answersNormally an an gen is _______ but some mes there are autoimmune
processes at work.
Inheritance of transmissible characteris cs or 'traits': such as blood group an gens found on red
blood cells
GENES -correct answersSpecific regions of the chromosome (________) encode the informa on
for specific traits.
46 -correct answersHumans have ___ chromosomes, which are present in 23 pairs-one member
of each pair is inherited from each parent
Traits -correct answers_____ are the observed or outward expression of genes.
protein -correct answersEach gene codes for the produc on of a specific ________ by coding for
a sequence of amino acids or polypep des.
RBC An gens -correct answersStructures embedded or protruding from the RBC membrane.
An gens found in body fluids such as saliva, plasma, semen etc.. -correct answersWhat are
Soluble blood group substances (an gens)?
Specific protein. -correct answersEach gene codes for the produc on of a
,allele. Alleles in the ABO blood group system are A, B, and O -correct answersAlternate form of
a gene at a specific locus is an ________.
detectable gene -correct answersA silent allele is a gene that produces no _______ ______
product. In the ABO system the O allele is a silent allele, or amorph, because it produces no
detectable gene product.
Co-Dominant Inheritance -correct answersWhen mul ple alleles are inherited and both gene
products are expressed, such as A and B which are expressed as type AB
Homozygous Inheritance -correct answersIt is the inheritance of iden cal alleles at a given locus
or loca on on both chromosomes. In an example from the ABO system it is inheri ng an A gene
from mom and an A gene from dad.
Heterozygous Inheritance -correct answersIt is the inheritance of different alleles at a given
locus on both chromosomes. In an example from the ABO system it is inheri ng an A gene from
mom and an O gene from dad
Genotype -correct answersIt is the gene c cons tu on of an individual
Phenotype -correct answersIt is the outward expression of inherited characteris cs
Dosage -correct answersIn some blood group systems, persons homozygous for an allele have
MORE an gen on their red cells than persons heterozygous for an allele.
Varia on in an gen expression due to the number of alleles present is called __________
Rh, Duffy, MNSs, and KIDD -correct answersBlood groups that demonstrate dosage include
,Gene Frequencies -correct answersFrequency of a gene in a certain popula on
phenotype frequencies -correct answersGene Frequencies can only be extrapolated from
popula on studies using ___________ _________
Centers for Medicare and Medicaid Services -correct answersRegulatory Agencies
(CMS)
Food and Drug Administra on -correct answersRegulatory Agencies
(FDA)
American Associa on of Blood Banks -correct answersAccredi ng Agencies
(AABB)
Joint Commission -correct answersAccredi ng Agencies
(JC)
College of American Pathologists -correct answersAccredi ng Agencies
(CAP)
Drug -correct answersFDA defines blood as a "_____" thus it regulates it under those standards.
Quality Assurance -correct answersThe overall process of quality improvement and
maintenance in the en re blood bank.
Quality Control -correct answersRou ne tes ng of Blood Bank Reagents to insure potency,
calibra on of serofuges, taking temps on fridges and freezers, tes ng blood components, etc.
, Current Good Manufacturing Prac ces (cGMP) -correct answersFollowing guidelines found in
Standard Opera ng Procedures (SOP).
CLIA '88 -correct answers________ states that clinical laboratories must have a Quality
Assurance Plan in place.
Immune Response -correct answersPhysiological mechanism to fight disease or clear foreign
substances
Primary immune response -correct answersFirst exposure of a foreign agent able to elicit an
immune response.
Secondary immune response -correct answersSubsequent exposure of the same foreign agent
An gen -correct answersAn ________ is a substance capable of elici ng an immune response
when introduced into an immuncompetent individual to whom it is foreign.
An genicity -correct answers___________ is the ability of an an gen to induce an immune
response and combine with specific an bodies
Epitopes -correct answersAn ________ is the part of the an gen that the an body finds foreign
and a aches to. It is the structural site where the an body combines with the an gen
Size, shape, loca on, and the number of determinants or epitopes -correct answersAn genicity
of an An gen is affected by its:
foreign -correct answersNormally an an gen is _______ but some mes there are autoimmune
processes at work.
