NURS 660 Exam 1:Psychopharmacology
Overview EXAM MOST TESTED
QUESTIONS AND VERIFIED
SOLUTIONS(Detailed Answers)GET IT
100% ACCURATE!! UPDATED VERSION
2026|2027!!!!!
Hyperprolactinemia causes - ANSWERS--adenoma
-drugs (SSRI, antipsychotics, cocaine)
-hypothyroidism
-mass effect
-trauma
Hyperprolactinemia Tx - ANSWERS-dopamine agonists (cabergoline, bromocriptine)
hyperprolactemia - ANSWERS-Higher-than-normal prolactin levels, which may result in
spontaneous breastmilk production and amenorrhea.
alpha 2 adrenergic receptors side effect - ANSWERS--Modulates alpha tone
-Counter regulatory for alpha-1 stimulation
-Inhibits norepinephrine
Risk of drug interactions
D2 receptor benefit - ANSWERS-Improves positive symptoms
,Postural hypotension (orthostatic hypotension) - ANSWERS-alpha 1 adrenergic side
effect
Sedation - ANSWERS-Histamine H1 side effect
What receptors are involved in weight gain? - ANSWERS-5HT2C weight changes + H1
sedation
alpha 1 adrenergic receptor side effects - ANSWERS-Orthostatic hypotension
Reflex tachycardia
Dizziness
muscarinic receptors side effect - ANSWERS-are normally activated by acetylcholine
ANS response
blurred vision, dry mouth, constipation, urinary retention, tachycardia, memory
D2 antagonism side effects - ANSWERS-receptors involved in dopamine transmission
decrease limbic activity
EPS, TD,
endocrine effects-prolactin secretion, sexual dysfunction
increase reward seeking behaviors
5HT2A receptors benefit - ANSWERS-Decreased EPS
CYP 450 inducers - ANSWERS-Carbamazepine, Phenobarbital, Phenytoin, Rifampin,
Griseofulvin
, CYP450 inhibitors - ANSWERS-CRACK AMIGOS: Cimetidine, Ritonavir (protease
inhibitor), Amiodarone, Ciprofloxacin, Ketoconazole (and other azoles), Acute alcohol
use, Macrolides, Isoniazid, Grapefruit Juice, Omeprazole, Sulfonamides
5HT2C benefit - ANSWERS-unknown
Histamine H1 - ANSWERS-Sedation
muscarinic receptor benefit - ANSWERS-Decrease EPS
alpha 1 adrenergic receptor benefit - ANSWERS-unknown
alpha 2 adrenergic benefit - ANSWERS-unknown
What do all antipsychotics have in common? - ANSWERS-They reduce dopaminergic
neurotransmission.
Volume of distribution (Vd) - ANSWERS-A ratio used to estimate the distribution of a
drug within the body relative to the total amount of fluid in the body. It is calculated as
the amount of drug administered divided by the plasma concentration of the drug.
Bioavailability - ANSWERS-A measure of the extent of drug absorption for a given drug
and route (from 0% to 100%).
Pharmacokinetics - ANSWERS-The method by which drugs are absorbed, distributed,
metabolized, and eliminated or excreted by the body.
Examples of low potency typical antipsychotics - ANSWERS-Chlorpromazine
(Thorazine), Thioridazine (Mellaril).
Overview EXAM MOST TESTED
QUESTIONS AND VERIFIED
SOLUTIONS(Detailed Answers)GET IT
100% ACCURATE!! UPDATED VERSION
2026|2027!!!!!
Hyperprolactinemia causes - ANSWERS--adenoma
-drugs (SSRI, antipsychotics, cocaine)
-hypothyroidism
-mass effect
-trauma
Hyperprolactinemia Tx - ANSWERS-dopamine agonists (cabergoline, bromocriptine)
hyperprolactemia - ANSWERS-Higher-than-normal prolactin levels, which may result in
spontaneous breastmilk production and amenorrhea.
alpha 2 adrenergic receptors side effect - ANSWERS--Modulates alpha tone
-Counter regulatory for alpha-1 stimulation
-Inhibits norepinephrine
Risk of drug interactions
D2 receptor benefit - ANSWERS-Improves positive symptoms
,Postural hypotension (orthostatic hypotension) - ANSWERS-alpha 1 adrenergic side
effect
Sedation - ANSWERS-Histamine H1 side effect
What receptors are involved in weight gain? - ANSWERS-5HT2C weight changes + H1
sedation
alpha 1 adrenergic receptor side effects - ANSWERS-Orthostatic hypotension
Reflex tachycardia
Dizziness
muscarinic receptors side effect - ANSWERS-are normally activated by acetylcholine
ANS response
blurred vision, dry mouth, constipation, urinary retention, tachycardia, memory
D2 antagonism side effects - ANSWERS-receptors involved in dopamine transmission
decrease limbic activity
EPS, TD,
endocrine effects-prolactin secretion, sexual dysfunction
increase reward seeking behaviors
5HT2A receptors benefit - ANSWERS-Decreased EPS
CYP 450 inducers - ANSWERS-Carbamazepine, Phenobarbital, Phenytoin, Rifampin,
Griseofulvin
, CYP450 inhibitors - ANSWERS-CRACK AMIGOS: Cimetidine, Ritonavir (protease
inhibitor), Amiodarone, Ciprofloxacin, Ketoconazole (and other azoles), Acute alcohol
use, Macrolides, Isoniazid, Grapefruit Juice, Omeprazole, Sulfonamides
5HT2C benefit - ANSWERS-unknown
Histamine H1 - ANSWERS-Sedation
muscarinic receptor benefit - ANSWERS-Decrease EPS
alpha 1 adrenergic receptor benefit - ANSWERS-unknown
alpha 2 adrenergic benefit - ANSWERS-unknown
What do all antipsychotics have in common? - ANSWERS-They reduce dopaminergic
neurotransmission.
Volume of distribution (Vd) - ANSWERS-A ratio used to estimate the distribution of a
drug within the body relative to the total amount of fluid in the body. It is calculated as
the amount of drug administered divided by the plasma concentration of the drug.
Bioavailability - ANSWERS-A measure of the extent of drug absorption for a given drug
and route (from 0% to 100%).
Pharmacokinetics - ANSWERS-The method by which drugs are absorbed, distributed,
metabolized, and eliminated or excreted by the body.
Examples of low potency typical antipsychotics - ANSWERS-Chlorpromazine
(Thorazine), Thioridazine (Mellaril).
