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CHEM 210|Biochem Module 3|Biochem Module 3 Study Guide| Updated Solution

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Module 3 : 3 Protein Structure & Conformation : 100s or 1000s aminos joined together change in -most proteins adopt a conformation when folded is either fibrous or globular : biological active snape =- - shape Imp . to function Structures Change In Intrinsically disordered (Randoml : Small 1 of proteins w entire structures that are random but functiona I function RULE : -most proteins need to adapt specific structures or similar structures to function bi vital link btwn the structure : function of proteins Primary structure : · order of amino acids , including disulfide bonds · proteins havea least 100 amino acids but could have residue chain · sea used to determine Polar : nonpolar stretches in protein. (1 letter abbrev Secondary structure : · examen local 3D structure of amino acid residues close in linear Sea ① Alpha-helices : - Coiled -backbone atoms form hydrogen bonds to stabilize sea. · standard helix : 3 .6 AA/residues ↳ 5. 4 anysforms (langsform = 1 x 100) All Aminos can be found ↳ Most Common : Alanine , arginine , . Leucine ↳ Not common : Proline glycine - no spacein helix ·Side Chains point out from helix to interact WI other side chains , water , or chemical species ↳ from noncovalent interactswl other aminos ② beta-sheets · repetitive sheet-like structure extended structure in zig-zag Orientation that put adjacent side Chain group far apart form invisible beta-strands that interact c hydrogen bonding

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Module 3 : Amino Acids Vocabulary
1 .

Transport Proteins help more molecules around the cell:
organism
2 .
Hormones molecules communicate
messages betun sells

3 .



Catalysis Enzymes speed up I catalyzeChem rxns

4.
Structure : Tissues
give strength to cells ,
organelles
Protection
5


. human itself from outside proteins : toxins antibodies
body protects =




.
6 Amino Acids monomers used as
building blocks

.
7
Storage Store O2

, Module 3 : Amino Acids
Transport : Proteins help more molecules around the cell: organism
Ex : Hemoglobin : blood-based protein that carries oxygen from lungs to tissue

Hormones molecules communicate betun sells
:
messages
Ex : Relaxin protein hormones
ligaments during delivery
:
helps women relax pelvic .




I
Catalysis :
Enzymes speed up CatalyzeChem rxns
Ex : Protease : breaks down proteins in cells to help
organisms recylce uneeded proteins
Ex : laundry detergent degrades stains :
/protein (blood (food
: Tissues
Structure :
give strength to cells organelles ,




Ex : Collagen : protein found in cartilage ,
skin , and tendons.


grouped by :
Amino Acids : Carboxylic


&
Y
Amine tant "-c-o
i Asid ① charge

② size
⑤ polarity
RIside chain-changes
Non-Polar Aliphatic
·
exists @ PH : 7 . 4
·
@pH 7 4
. all carboxylic acids Would have lost -

cool group
.



Single bonds
·
Almost all amino acids group would have Extra-NHz@PH74
Interactw other groups
·




Interior part of
·
protein
-




Glycine Alanine Valine

Gly Ald ral
G A V O
11
P ⑮ HzNt CH
-



C 0
-




HgNt
CHa CH
0-
HzNt
-



CH CO
CHz
-




H C +3


Proline Leucine Isoleucine
Pro Leu IIe
-




P 2 U I E
Il
HzNt-CH C O-
- -




HzN +
W HzNt CH C-0-
CH CH3
It -




C- 0- CH2
CH CH2
CH3
CH3
-




unique : Not Flexible
CH3
·



rigid

Methionine Y
et HzNt-CH-c- 0-
M (+ 2

CHz

"He

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