AAMC FL 1 FULL REVIEW- Chem/Phys Test Questions with
Verified Answers
In the chromatography of the reaction mixture,
water absorbed on cellulose functioned as the C- passage has right before the figure of the
stationary phase. What was the principal factor reaction: "scientists have studied the production
determining the migration of individual of amino acids under conditions that simulate
components in the sample? those of primitive Earth."
A.Hydrogen bonding ^^^^this indicates that C is the right answer.
B.Solute concentration
C.Stationary phase concentration
D.Thickness of paper - ANSWER -B and D According to the developed chromatography
are dumb options. Knock them out. plate shown below, what is the approximate Rf
value of aspartic acid? - ANSWER -Rf:
hydrogen bonding to the stationary phase will distance travelled by analyze/distance traveled
determine the relative rate of migration of the by solvent.
various components in the sample.
2/10---> 0.2
When thinking migration, think bonding. If it
bonds super well, it isn't going to move very far.
Which of the following statements does NOT
correctly describe the dehydration of malic acid to
What assumption is being made if scientists fumaric acid and maleic acid?
conclude that aspartic acid was formed by the
prebiological synthesis in the passage? A.The reaction occurs most readily with tertiary
alcohols.
A.Aspartic acid is unstable at temperatures
below 150°C. B.The reaction involves the loss of a water
molecule.
B.All of the malic acid underwent the dehydration
reaction to form fumaric/maleic acid. C.The reaction has a carbocation intermediate.
C.Compound A and cyanide were available on D.The reaction is stereospecific. -
primitive Earth. ANSWER -NOT is the key word.
D.The reaction between ammonia and fumaric DEHYDRATION involves:
acid was catalyzed by the presence of water. -
ANSWER -POE: -loss of a water molecule (cross b out)
-it does have a carbocation (sn1)
D- is wrong. water is not a catalyst -and does like tert substitutions (snl)
B- some of the magic acid was turned to aspartic D is wrong. Two products are made, therefore it
acid in the next equation. WRONG. is not stereospecific.
A- the 150 degrees comes into play when the
scientists are doing the actual experiment, NOT What type of functional group is formed when
the synthesis. aspartic acid reacts with another amino acid to
, AAMC FL 1 FULL REVIEW- Chem/Phys Test Questions with
Verified Answers
form a peptide bond? hydrogens which increases steric hindrance at
that site. Which is actually the only thing that
A.An amine group matters since the nucleophile will be attacking
B.An aldehyde group that carbon and not the oxygen that presumably
C.An amide group already left the molecule as H20. D is correct.
D.A carboxyl group - ANSWER -C. amide
is the other end of the peptide bond!
Hydride shifts - ANSWER -are not DIRECT
peptide bond= carboxyl group reacts with amine, products.
making a c=o next to an N which is an amide direct products= products without rearrangement.
If 2-pentanol replaces 1-pentanol in the reaction If a solution containing the compounds shown in
shown in Figure 3, the rate of substitution is less Figure 4, is injected into a gas-liquid
because: chromatograph, the first peak observed in the gc
trace is attributable to which compound?
A.the C-O bond in 2-pentanol is stronger than
the C-O bond in 1-pentanol. A.2-Methyl-2-butanol
B.2-Methyl-2-butene
B.there is a competing elimination reaction that C.2-Chloro-2-methylbutane
slows the rate of substitution. D.2-Bromo-2-methylbutane - ANSWER -
Gas chromatography will elute the LIGHTEST
C.there is more steric hindrance at the oxygen molecular weight FIRST. B is the lightest
atom in 2-pentanol than in 1-pentanol, making compound
protonation less likely.
D.there is more steric hindrance at the 2-position Chirality - ANSWER -if lowest priority is on
of 2-pentanol than at the 1-position of 1- a wedge, flip the stereochemistry. if on dash, you
pentanol. - ANSWER -Figure 3 shows an gucci
SN2 reaction. You know that SN2 reactions hate
steric hinderance. It literally will not go with a
tertiary one, but is hella slow with a secondary In determining which reactant loses the -OH
one. group, which of the following isotopic
substitutions would be most useful?
The steric hinderance is not at the oxygen. It's
talking about all the other crap. A.Replace the acidic H of acetic acid with D.
B.Replace the alcoholic H of ethanol with D.
What's important is the Halide being able to C.Replace the carbonyl oxygen of acetic acid
attack the carbocation intermediate, which is with O-18.
made more difficult by hinderance from the extra D.Replace the hydroxyl oxygen of ethanol with O-
alkyl groups since it's further down the chain 18. - ANSWER -D. this would be the
oxygen that is added to the product
The oxygen isn't sterically hindered. Its actually
pretty available to be protonated. The carbon
however is surrounded by other carbons and A person, whose eye has a lens-to-retina
Verified Answers
In the chromatography of the reaction mixture,
water absorbed on cellulose functioned as the C- passage has right before the figure of the
stationary phase. What was the principal factor reaction: "scientists have studied the production
determining the migration of individual of amino acids under conditions that simulate
components in the sample? those of primitive Earth."
A.Hydrogen bonding ^^^^this indicates that C is the right answer.
B.Solute concentration
C.Stationary phase concentration
D.Thickness of paper - ANSWER -B and D According to the developed chromatography
are dumb options. Knock them out. plate shown below, what is the approximate Rf
value of aspartic acid? - ANSWER -Rf:
hydrogen bonding to the stationary phase will distance travelled by analyze/distance traveled
determine the relative rate of migration of the by solvent.
various components in the sample.
2/10---> 0.2
When thinking migration, think bonding. If it
bonds super well, it isn't going to move very far.
Which of the following statements does NOT
correctly describe the dehydration of malic acid to
What assumption is being made if scientists fumaric acid and maleic acid?
conclude that aspartic acid was formed by the
prebiological synthesis in the passage? A.The reaction occurs most readily with tertiary
alcohols.
A.Aspartic acid is unstable at temperatures
below 150°C. B.The reaction involves the loss of a water
molecule.
B.All of the malic acid underwent the dehydration
reaction to form fumaric/maleic acid. C.The reaction has a carbocation intermediate.
C.Compound A and cyanide were available on D.The reaction is stereospecific. -
primitive Earth. ANSWER -NOT is the key word.
D.The reaction between ammonia and fumaric DEHYDRATION involves:
acid was catalyzed by the presence of water. -
ANSWER -POE: -loss of a water molecule (cross b out)
-it does have a carbocation (sn1)
D- is wrong. water is not a catalyst -and does like tert substitutions (snl)
B- some of the magic acid was turned to aspartic D is wrong. Two products are made, therefore it
acid in the next equation. WRONG. is not stereospecific.
A- the 150 degrees comes into play when the
scientists are doing the actual experiment, NOT What type of functional group is formed when
the synthesis. aspartic acid reacts with another amino acid to
, AAMC FL 1 FULL REVIEW- Chem/Phys Test Questions with
Verified Answers
form a peptide bond? hydrogens which increases steric hindrance at
that site. Which is actually the only thing that
A.An amine group matters since the nucleophile will be attacking
B.An aldehyde group that carbon and not the oxygen that presumably
C.An amide group already left the molecule as H20. D is correct.
D.A carboxyl group - ANSWER -C. amide
is the other end of the peptide bond!
Hydride shifts - ANSWER -are not DIRECT
peptide bond= carboxyl group reacts with amine, products.
making a c=o next to an N which is an amide direct products= products without rearrangement.
If 2-pentanol replaces 1-pentanol in the reaction If a solution containing the compounds shown in
shown in Figure 3, the rate of substitution is less Figure 4, is injected into a gas-liquid
because: chromatograph, the first peak observed in the gc
trace is attributable to which compound?
A.the C-O bond in 2-pentanol is stronger than
the C-O bond in 1-pentanol. A.2-Methyl-2-butanol
B.2-Methyl-2-butene
B.there is a competing elimination reaction that C.2-Chloro-2-methylbutane
slows the rate of substitution. D.2-Bromo-2-methylbutane - ANSWER -
Gas chromatography will elute the LIGHTEST
C.there is more steric hindrance at the oxygen molecular weight FIRST. B is the lightest
atom in 2-pentanol than in 1-pentanol, making compound
protonation less likely.
D.there is more steric hindrance at the 2-position Chirality - ANSWER -if lowest priority is on
of 2-pentanol than at the 1-position of 1- a wedge, flip the stereochemistry. if on dash, you
pentanol. - ANSWER -Figure 3 shows an gucci
SN2 reaction. You know that SN2 reactions hate
steric hinderance. It literally will not go with a
tertiary one, but is hella slow with a secondary In determining which reactant loses the -OH
one. group, which of the following isotopic
substitutions would be most useful?
The steric hinderance is not at the oxygen. It's
talking about all the other crap. A.Replace the acidic H of acetic acid with D.
B.Replace the alcoholic H of ethanol with D.
What's important is the Halide being able to C.Replace the carbonyl oxygen of acetic acid
attack the carbocation intermediate, which is with O-18.
made more difficult by hinderance from the extra D.Replace the hydroxyl oxygen of ethanol with O-
alkyl groups since it's further down the chain 18. - ANSWER -D. this would be the
oxygen that is added to the product
The oxygen isn't sterically hindered. Its actually
pretty available to be protonated. The carbon
however is surrounded by other carbons and A person, whose eye has a lens-to-retina
