NURS 660 EXAM 1 2026 EXAM SCRIPT FULL
QUESTIONS AND DETAILED ANSWERS
GRADED A+
⩥ Serotonin 5HT2c receptor. Answer: The benefit of this receptor is
unknown
Side effect is weight gain
⩥ Histamine H-1 receptor. Answer: The benefit of this receptor is
sedation
Side effects are sedation, increased appetite, weight gain and
hypotension
⩥ Muscarinic cholinergic receptors. Answer: The benefit of the receptor
is that it reduces EPS
Side effects are autonomic changes such as blurry vision, dry mouth,
constipation, urinary retention, tachycardia and memory dysfunction.
⩥ a1-adrenergic receptors. Answer: Benefit of receptor unknown
Side effects are orthostatic hypertension, dizziness and reflex
tachycardia.
⩥ a2-adrenergic receptors. Answer: Benefit of receptor unknown
, Side effects are drug interactions
⩥ D2-Agonist actions?. Answer: What makes an antipsychotic
conventional?
⩥ D2 antagonist/First generation antipsychotics/Conventional
antipsychotics/Typical antipsychotics. Answer: These antipsychotics
share the primary pharmacological property of D2 antagonism, which is
responsible not only for their antipsychotic efficacy, but also for many of
their side effects.
⩥ Conventional Antipsychotic. Answer: These drugs have
pharmacological properties in addition to D2 antagonism, they block
muscarinic cholinergic receptors, histamine h-1 receptors and/or a1-
adrenergic receptors.
⩥ 60-80%. Answer: Antipsychotic properties happen when how much of
the D2 receptor is blocked?
⩥ 80%. Answer: The degree of binding in the mesolimbic pathway
needed for antipsychotic effects is?
⩥ extrapyramidal side effects. Answer: When greater that 80% of D2
receptors are occupied in the dorsal striatum what happens?
QUESTIONS AND DETAILED ANSWERS
GRADED A+
⩥ Serotonin 5HT2c receptor. Answer: The benefit of this receptor is
unknown
Side effect is weight gain
⩥ Histamine H-1 receptor. Answer: The benefit of this receptor is
sedation
Side effects are sedation, increased appetite, weight gain and
hypotension
⩥ Muscarinic cholinergic receptors. Answer: The benefit of the receptor
is that it reduces EPS
Side effects are autonomic changes such as blurry vision, dry mouth,
constipation, urinary retention, tachycardia and memory dysfunction.
⩥ a1-adrenergic receptors. Answer: Benefit of receptor unknown
Side effects are orthostatic hypertension, dizziness and reflex
tachycardia.
⩥ a2-adrenergic receptors. Answer: Benefit of receptor unknown
, Side effects are drug interactions
⩥ D2-Agonist actions?. Answer: What makes an antipsychotic
conventional?
⩥ D2 antagonist/First generation antipsychotics/Conventional
antipsychotics/Typical antipsychotics. Answer: These antipsychotics
share the primary pharmacological property of D2 antagonism, which is
responsible not only for their antipsychotic efficacy, but also for many of
their side effects.
⩥ Conventional Antipsychotic. Answer: These drugs have
pharmacological properties in addition to D2 antagonism, they block
muscarinic cholinergic receptors, histamine h-1 receptors and/or a1-
adrenergic receptors.
⩥ 60-80%. Answer: Antipsychotic properties happen when how much of
the D2 receptor is blocked?
⩥ 80%. Answer: The degree of binding in the mesolimbic pathway
needed for antipsychotic effects is?
⩥ extrapyramidal side effects. Answer: When greater that 80% of D2
receptors are occupied in the dorsal striatum what happens?
