NR 566 Midterm Exam Study Guide | 2026 Advanced Nursing Prep
Which non-amphetamines are FDA approved for weight loss that have lower abuse risk? -
(answer)Phentermine and Diethylpropion
How does Phentermine and Diethylpropion promote weight loss? - (answer)-Promote weight loss by
decreasing appetite
-They are central nervous system (CNS) stimulants that suppress appetite by increasing the availability
of norepinephrine at receptors in the brain
What is the maximum recommended duration of use for non-amphetamines? - (answer)3 months or
less
What drug schedule are Phentermine and Diethylpropion under? - (answer)Schedule IV
What labs should be monitored with Phentermine and Diethylpropion? What condition should we
screen for? - (answer)-baseline CMP (watch electrolytes and creatinine)
-screen for depression
Phentermine adverse effects - (answer)-increase HR and BP
-dry mouth and constipation
What is role of topiramate in weight loss? - (answer)Increases satiety
What are some Phentermine/topiramate contraindications for use? - (answer)not approved in children
and contraindicated with severe hepatic impairment
How should we educate patient to take Phentermine/topiramate to avoid insomnia? - (answer)given
before 1600
What are some high-risk patient conditions that we should use Phentermine/topiramate with caution? -
(answer)hx drug abuse, glaucoma, pregnant, HTN, hyperthyroidism
,NR 566 Midterm Exam Study Guide | 2026 Advanced Nursing Prep
Phentermine/topiramate adverse effects - (answer)insomnia, nervousness, anxiety, depression, blurred
vision
Which of the following would be a contraindication to prescribing phentermine/topiramate? Select all
that apply. - (answer)A) Glaucoma
B) Hypothyroidism
C) Hypertension
D) Hyperthyroidism
E) Vitamin D Deficiency
F) A, B, E
ANSWER: A,C,D
Orlistat is a lipase inhibitor that acts on the _________ and reduces absorption of fat by 30%. -
(answer)GI tract
Take multivitamin ___hours before/after to supplement fat-soluble vitamins that may not be absorbed
well when taking Orlistat. - (answer)2
Orlistat is OTC as 60 mg TID with meals. Not approved in children <____. - (answer)12
Orlistat results in the least amount of weight loss of all. How much? - (answer)2-3% body weight (7 lbs in
year)
Orlistat adverse effects - (answer)Fecal incontinence, oily rectal leakage, flatus, abdominal cramps. liver
damage (light-colored stools, dark urine, fatigue, jaundice, anorexia)
When is Orlistat contraindicated? - (answer)In those with malabsorption syndrome or cholestasis
,NR 566 Midterm Exam Study Guide | 2026 Advanced Nursing Prep
What vitamin deficiency are we concerned about when taking Orlistat...especially if the patient is on
coumadin? - (answer)Monitor Coumadin as Vitamin K deficiency may occur and intensify effect of
Coumadin.
A patient with a BMI of 27 would be considered: - (answer)overweight
Lorcaserin adverse effects - (answer)headache, URI, back pain, hypoglycemia (in DM), blood dyscrasias,
cognitive impairment, psychiatric disorders, priapism, pulmonary hypertension, and valvular heart
disease
Lorcaserin MOA - (answer)Reduces waist circumference, fasting glucose, insulin, total cholesterol, LDL,
triglycerides
When is Lorcaserin contraindicated? - (answer)CrCl <30
-Not approved in children
Lorcaserin drug interactions - (answer)-MAOI inhibitors, SSRIs, SNRIs, St. Johns wart, and triptans
-Increased risk for serotonin syndrome
Naltrexone and Bupropion black box warning - (answer)increased risk for suicidal ideation and suicide
attempts in children, adolescents, and young adults
Do not take Naltrexone and Bupropion within ___weeks of taking a _____. - (answer)-two
-MAOI
Due to Naltrexone and Bupropion antagonist effects, it can reduce effects of what? - (answer)opioids
Naltrexone and Bupropion contraindications - (answer)HTN, seizure disorders, eating disorders, alcohol
or drug withdrawal
, NR 566 Midterm Exam Study Guide | 2026 Advanced Nursing Prep
Liraglutide MOA - (answer)-promotes weight loss by slowing gastric emptying
-increases satiety
-Not approved children.
When taking Liraglutide, it is not unusual for baseline HR to increase ______bpm - (answer)10-20
-monitor for tachycardia
When taking Liraglutide, monitor for ________ in patients with diabetes - (answer)hypoglycemia
Baseline labs for Liraglutide - (answer)lipids, CMP, HgA1C q 6 months, triglycerides
Liraglutide black box warning - (answer)associated with a risk for thyroid C-cell tumors based on studies
in rodents
-Contraindicated in people with multiple endocrine neoplasia syndrome type 2 (MEN 2) or
personal/family history of medullary thyroid carcinoma
Those trying to LOSE weight should exercise at least ____ min/week or more - (answer)150
What BMI is bariatric surgery considered? - (answer)35 or more
Common procedures:
-Gastric Bypass Surgery (Roux-en-Y procedure)
-Laparoscopic implantation of an adjustable gastric band
What is typical weight loss for those who diligently adhere to medication and lifestyle therapy?____%
whereas >____% is exceptional - (answer)10-15%
> 15%
Most weight loss occurs during the first ___ months of treatment - (answer)6
Which non-amphetamines are FDA approved for weight loss that have lower abuse risk? -
(answer)Phentermine and Diethylpropion
How does Phentermine and Diethylpropion promote weight loss? - (answer)-Promote weight loss by
decreasing appetite
-They are central nervous system (CNS) stimulants that suppress appetite by increasing the availability
of norepinephrine at receptors in the brain
What is the maximum recommended duration of use for non-amphetamines? - (answer)3 months or
less
What drug schedule are Phentermine and Diethylpropion under? - (answer)Schedule IV
What labs should be monitored with Phentermine and Diethylpropion? What condition should we
screen for? - (answer)-baseline CMP (watch electrolytes and creatinine)
-screen for depression
Phentermine adverse effects - (answer)-increase HR and BP
-dry mouth and constipation
What is role of topiramate in weight loss? - (answer)Increases satiety
What are some Phentermine/topiramate contraindications for use? - (answer)not approved in children
and contraindicated with severe hepatic impairment
How should we educate patient to take Phentermine/topiramate to avoid insomnia? - (answer)given
before 1600
What are some high-risk patient conditions that we should use Phentermine/topiramate with caution? -
(answer)hx drug abuse, glaucoma, pregnant, HTN, hyperthyroidism
,NR 566 Midterm Exam Study Guide | 2026 Advanced Nursing Prep
Phentermine/topiramate adverse effects - (answer)insomnia, nervousness, anxiety, depression, blurred
vision
Which of the following would be a contraindication to prescribing phentermine/topiramate? Select all
that apply. - (answer)A) Glaucoma
B) Hypothyroidism
C) Hypertension
D) Hyperthyroidism
E) Vitamin D Deficiency
F) A, B, E
ANSWER: A,C,D
Orlistat is a lipase inhibitor that acts on the _________ and reduces absorption of fat by 30%. -
(answer)GI tract
Take multivitamin ___hours before/after to supplement fat-soluble vitamins that may not be absorbed
well when taking Orlistat. - (answer)2
Orlistat is OTC as 60 mg TID with meals. Not approved in children <____. - (answer)12
Orlistat results in the least amount of weight loss of all. How much? - (answer)2-3% body weight (7 lbs in
year)
Orlistat adverse effects - (answer)Fecal incontinence, oily rectal leakage, flatus, abdominal cramps. liver
damage (light-colored stools, dark urine, fatigue, jaundice, anorexia)
When is Orlistat contraindicated? - (answer)In those with malabsorption syndrome or cholestasis
,NR 566 Midterm Exam Study Guide | 2026 Advanced Nursing Prep
What vitamin deficiency are we concerned about when taking Orlistat...especially if the patient is on
coumadin? - (answer)Monitor Coumadin as Vitamin K deficiency may occur and intensify effect of
Coumadin.
A patient with a BMI of 27 would be considered: - (answer)overweight
Lorcaserin adverse effects - (answer)headache, URI, back pain, hypoglycemia (in DM), blood dyscrasias,
cognitive impairment, psychiatric disorders, priapism, pulmonary hypertension, and valvular heart
disease
Lorcaserin MOA - (answer)Reduces waist circumference, fasting glucose, insulin, total cholesterol, LDL,
triglycerides
When is Lorcaserin contraindicated? - (answer)CrCl <30
-Not approved in children
Lorcaserin drug interactions - (answer)-MAOI inhibitors, SSRIs, SNRIs, St. Johns wart, and triptans
-Increased risk for serotonin syndrome
Naltrexone and Bupropion black box warning - (answer)increased risk for suicidal ideation and suicide
attempts in children, adolescents, and young adults
Do not take Naltrexone and Bupropion within ___weeks of taking a _____. - (answer)-two
-MAOI
Due to Naltrexone and Bupropion antagonist effects, it can reduce effects of what? - (answer)opioids
Naltrexone and Bupropion contraindications - (answer)HTN, seizure disorders, eating disorders, alcohol
or drug withdrawal
, NR 566 Midterm Exam Study Guide | 2026 Advanced Nursing Prep
Liraglutide MOA - (answer)-promotes weight loss by slowing gastric emptying
-increases satiety
-Not approved children.
When taking Liraglutide, it is not unusual for baseline HR to increase ______bpm - (answer)10-20
-monitor for tachycardia
When taking Liraglutide, monitor for ________ in patients with diabetes - (answer)hypoglycemia
Baseline labs for Liraglutide - (answer)lipids, CMP, HgA1C q 6 months, triglycerides
Liraglutide black box warning - (answer)associated with a risk for thyroid C-cell tumors based on studies
in rodents
-Contraindicated in people with multiple endocrine neoplasia syndrome type 2 (MEN 2) or
personal/family history of medullary thyroid carcinoma
Those trying to LOSE weight should exercise at least ____ min/week or more - (answer)150
What BMI is bariatric surgery considered? - (answer)35 or more
Common procedures:
-Gastric Bypass Surgery (Roux-en-Y procedure)
-Laparoscopic implantation of an adjustable gastric band
What is typical weight loss for those who diligently adhere to medication and lifestyle therapy?____%
whereas >____% is exceptional - (answer)10-15%
> 15%
Most weight loss occurs during the first ___ months of treatment - (answer)6
