1
NR 507 EDAPT – ENDOCRINE SYSTEM EXAM 2026
LATEST VERSION QUESTIONS AND ANSWERS
SECTION 1: Endocrine Physiology & Regulation (Q1–Q20)
Q1. The primary function of the endocrine system is to:
A. Provide rapid neural responses
B. Regulate long-term physiological processes
C. Control voluntary movement
D. Maintain immune defense
Correct Answer: B
Rationale: Endocrine hormones regulate growth, metabolism,
reproduction, and homeostasis over time.
,2
Q2. Hormones exert their effects by binding to:
A. DNA directly
B. Enzymes
C. Specific receptors
D. Ion channels only
Correct Answer: C
Rationale: Hormones are target-specific, requiring receptor
binding to initiate action.
Q3. Steroid hormones differ from peptide hormones because
they:
A. Bind cell membrane receptors
B. Act via second messengers
C. Are lipid soluble
D. Are stored in vesicles
Correct Answer: C
Rationale: Steroid hormones are lipid soluble and cross cell
membranes.
Q4. Negative feedback regulation occurs when:
A. Hormone secretion increases continuously
B. The end product inhibits its own release
,3
C. Hormones act independently
D. Target organs override control
Correct Answer: B
Rationale: Negative feedback maintains hormonal balance.
Q5. Which gland is considered the “master gland”?
A. Thyroid
B. Adrenal
C. Pituitary
D. Hypothalamus
Correct Answer: C
Rationale: The pituitary regulates other endocrine glands.
Q6. The hypothalamus links the endocrine and nervous
systems through:
A. Direct hormone secretion
B. Autonomic nerves
C. Pituitary control
D. Feedback loops only
Correct Answer: C
Rationale: It controls the pituitary via releasing and inhibiting
hormones.
, 4
Q7. Second messenger systems are MOST commonly
associated with:
A. Steroid hormones
B. Thyroid hormones
C. Peptide hormones
D. Mineralocorticoids
Correct Answer: C
Rationale: Peptide hormones use cAMP, IP3, or Ca²⁺ pathways.
Q8. Which hormone uses intracellular receptors?
A. Insulin
B. Glucagon
C. Cortisol
D. Parathyroid hormone
Correct Answer: C
Rationale: Cortisol is a steroid hormone acting inside the cell.
Q9. Circadian rhythm MOST influences secretion of:
A. Aldosterone
B. Cortisol
NR 507 EDAPT – ENDOCRINE SYSTEM EXAM 2026
LATEST VERSION QUESTIONS AND ANSWERS
SECTION 1: Endocrine Physiology & Regulation (Q1–Q20)
Q1. The primary function of the endocrine system is to:
A. Provide rapid neural responses
B. Regulate long-term physiological processes
C. Control voluntary movement
D. Maintain immune defense
Correct Answer: B
Rationale: Endocrine hormones regulate growth, metabolism,
reproduction, and homeostasis over time.
,2
Q2. Hormones exert their effects by binding to:
A. DNA directly
B. Enzymes
C. Specific receptors
D. Ion channels only
Correct Answer: C
Rationale: Hormones are target-specific, requiring receptor
binding to initiate action.
Q3. Steroid hormones differ from peptide hormones because
they:
A. Bind cell membrane receptors
B. Act via second messengers
C. Are lipid soluble
D. Are stored in vesicles
Correct Answer: C
Rationale: Steroid hormones are lipid soluble and cross cell
membranes.
Q4. Negative feedback regulation occurs when:
A. Hormone secretion increases continuously
B. The end product inhibits its own release
,3
C. Hormones act independently
D. Target organs override control
Correct Answer: B
Rationale: Negative feedback maintains hormonal balance.
Q5. Which gland is considered the “master gland”?
A. Thyroid
B. Adrenal
C. Pituitary
D. Hypothalamus
Correct Answer: C
Rationale: The pituitary regulates other endocrine glands.
Q6. The hypothalamus links the endocrine and nervous
systems through:
A. Direct hormone secretion
B. Autonomic nerves
C. Pituitary control
D. Feedback loops only
Correct Answer: C
Rationale: It controls the pituitary via releasing and inhibiting
hormones.
, 4
Q7. Second messenger systems are MOST commonly
associated with:
A. Steroid hormones
B. Thyroid hormones
C. Peptide hormones
D. Mineralocorticoids
Correct Answer: C
Rationale: Peptide hormones use cAMP, IP3, or Ca²⁺ pathways.
Q8. Which hormone uses intracellular receptors?
A. Insulin
B. Glucagon
C. Cortisol
D. Parathyroid hormone
Correct Answer: C
Rationale: Cortisol is a steroid hormone acting inside the cell.
Q9. Circadian rhythm MOST influences secretion of:
A. Aldosterone
B. Cortisol
